ZFIN ID: ZDB-PUB-021017-41
Xenopus laevis embryos share antigens with zebrafish embryos and with human malignant neoplasms
Biava, P., Monguzzi, A., Bonsignorio, D., Frosi, A., Sell, S., and Klavins, J.V.
Previous experiments have demonstrated that antigens present in Xenopus laevis embryos are shared with human malignant neoplasms. In fact it is known that antisera raised in rabbit against pellet and supernatant fractions of Xenopus laevis embryos react to different antigens present in human tumors. The aim of the the present study was to evaluate whether these antisera react also to different antigens contained in zebrafish embryos at different stages of cell differentiation. This was done with the agar-gel immunodiffusion method performed according to an already described protocol.
The results that we obtained show that both antisera raised in against pellet and supernatant fractions of Xenopus laevis embryos react to antigens of zebrafish at different stages of cell differentiation.
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