PUBLICATION

Headwaters of the zebrafish — emergence of a new model vertebrate

Authors
Grunwald, D.J. and Eisen, J.S.
ID
ZDB-PUB-020912-16
Date
2002
Source
Nature reviews. Genetics   3(9): 717-724 (Review)
Registered Authors
Eisen, Judith S., Grunwald, David
Keywords
none
MeSH Terms
  • Animals
  • Embryo, Nonmammalian/physiology
  • Models, Genetic
  • Morphogenesis/genetics
  • Research/trends
  • Vertebrates/genetics*
  • Zebrafish/embryology
  • Zebrafish/genetics*
PubMed
12209146 Full text @ Nat. Rev. Genet.
Abstract
The understanding of vertebrate development has advanced considerably in recent years, primarily due to the study of a few model organisms. The zebrafish, the newest of these models, has risen to prominence because both genetic and experimental embryological methods can be easily applied to this animal. The combination of approaches has proven powerful, yielding insights into the formation and function of individual tissues, organ systems and neural networks, and into human disease mechanisms. Here, we provide a personal perspective on the history of zebrafish research, from the assembly of the first genetic and embryological tools through to sequencing of the genome.
Genes / Markers
Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes