ZFIN ID: ZDB-PUB-020701-2
Pseudocapillaria tomentosa, a nematode pathogen, and associated neoplasms of zebrafish (Danio rerio) kept in research colonies
Kent, M.L., Bishop-Stewart, J.K., Matthews, J.L., and Spitsbergen, J.M.
Date: 2002
Source: Comparative medicine   52(4): 354-358 (Journal)
Registered Authors: Bishop-Stewart, Janell, Kent, Michael, Matthews, Jennifer, Spitsbergen, Jan
Keywords: none
MeSH Terms:
  • Animals
  • Animals, Laboratory
  • Female
  • Intestinal Neoplasms/parasitology
  • Intestinal Neoplasms/pathology
  • Intestinal Neoplasms/veterinary*
  • Male
  • Nematoda/anatomy & histology
  • Nematoda/physiology*
  • Nematode Infections/pathology
  • Nematode Infections/veterinary*
  • Zebrafish/parasitology*
PubMed: 12211280
Infections with capillarid nematodes were observed in zebrafish (Danio rerio) kept at several research facilities and in a large carcinogen exposure study previously conducted at Oregon State University. We report a morphologic description that identifies the worm as Pseudocapillaria tomentosa, a common nematode of cyprinid and other fishes. Pathologic lesions associated with the infection ranged from inflammatory changes to aggressive neoplasms of the intestine (i.e., intestinal carcinomas and mixed malignant neoplasms). Capillarid nematodes may have intermediate or paratenic hosts. Using a laboratory transmission study, we confirmed that the parasite has a direct life cycle.