ZFIN ID: ZDB-PUB-011214-3
Pattern formation in the zebrafish retina
Neumann, C.J.
Date: 2001
Source: Seminars in cell & developmental biology   12(6): 485-490 (Review)
Registered Authors: Neumann, Carl J.
Keywords: zebrafish, retina neurogenesis, Hedgehog, Xenopus retina, cell differentiation, behavioral screen, ganglion cells, proneural gene, Danio rerio, hedgehog, mutations, neurogenesis, mechanisms
MeSH Terms:
  • Animals
  • Autonomic Nervous System/embryology*
  • Body Patterning*
  • Cell Differentiation
  • Hedgehog Proteins
  • Membrane Proteins/metabolism
  • Models, Animal
  • Receptors, Notch
  • Retina/embryology*
  • Signal Transduction
  • Trans-Activators/genetics*
  • Trans-Activators/physiology
  • Zebrafish/embryology*
PubMed: 11735384 Full text @ Sem. Cell Dev. Biol.
During the past 15 years, the zebrafish has become established as a genetic model organism to study vertebrate development. It is particularly well suited for the analysis of the retina, and several genetic screens have yielded a large number of mutants affecting retinal development. Most of these mutants still await thorough analysis and molecular characterization, but work on a handful of genes has already generated interesting results that shed some light on patterning mechanisms employed in the vertebrate retina.