PUBLICATION
The zebrafish as a model visual system
- Authors
- Bilotta, J. and Saszik S.
- ID
- ZDB-PUB-011116-2
- Date
- 2001
- Source
- International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 19(7): 621-629 (Journal)
- Registered Authors
- Bilotta, Joe
- Keywords
- Danio rerio; zebrafish; visual development; animal models; visual neuroscience, Brachydanio rerio, retinotectal projection, retinal development, spectral sensitivity, embryonic zebrafish, behavioral screen, adult zebrafish, ventral retina, bipolar cells
- MeSH Terms
-
- Aging/physiology*
- Animals
- Brain/cytology
- Brain/growth & development
- Brain/physiology*
- Models, Animal*
- Mutation/physiology*
- Retina/cytology
- Retina/growth & development
- Retina/physiology*
- Visual Pathways/cytology
- Visual Pathways/growth & development
- Visual Pathways/physiology*
- Zebrafish/anatomy & histology
- Zebrafish/growth & development
- Zebrafish/physiology*
- PubMed
- 11705666 Full text @ Int. J. Dev. Neurosci.
Citation
Bilotta, J. and Saszik S. (2001) The zebrafish as a model visual system. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 19(7):621-629.
Abstract
The zebrafish has bacome an important vertebrate model in developmental neuroscience because it is a useful model for embryology, developmental biology, and genetic analysis. The similarities of its visual system to that of other vertebrates also make this animal a valuable model in vision science. The anatomical, physiological, and behavioral components of zebrafish visual processing have been studied in adult and in developing zebrafish. Its retinal anatomy continues to develop following hatching, providing an opportunity to correlate the development of retinal structure with visual physiology and behavior. In addition, a number of genetic mutations have been developed which are used to examine the contributions of genetics to visual development and function. This article will provide an overview of studies of zebrafish anatomical, physiological and behavioral processing, and the effects if genetic and environmental manipulations on visual development.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping