PUBLICATION
Caged Q-rhodamine dextran: a new photoactivated fluorescent tracer
- Authors
- Gee, K.R., Weinberg, E.S., and Kozlowski, D.J.
- ID
- ZDB-PUB-010912-26
- Date
- 2001
- Source
- Bioorganic & medicinal chemistry letters 11(16): 2181-2183 (Journal)
- Registered Authors
- Kozlowski, David J., Weinberg, Eric
- Keywords
- none
- MeSH Terms
-
- Animals
- Dextrans/chemical synthesis*
- Dextrans/chemistry
- Embryo, Nonmammalian
- Fluorescent Dyes/chemical synthesis*
- Fluorescent Dyes/chemistry
- Microscopy, Fluorescence
- Photochemistry
- Rhodamines/chemical synthesis*
- Rhodamines/chemistry
- Zebrafish
- PubMed
- 11514165 Full text @ Bioorg. Med. Chem. Lett.
Citation
Gee, K.R., Weinberg, E.S., and Kozlowski, D.J. (2001) Caged Q-rhodamine dextran: a new photoactivated fluorescent tracer. Bioorganic & medicinal chemistry letters. 11(16):2181-2183.
Abstract
An amine-reactive caged rhodamine was synthesized and conjugated to aminodextran. The resulting tracer was injected into a single cell zebrafish embryo, and a portion of the tracer was photolyzed in a single cell after development. The resulting fluorescent cell was imaged by fluorescence microscopy through a single round of cell division.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping