PUBLICATION
Zebrafish mutants: Behavioral genetic studies of visual system defects
- Authors
- Li, L.
- ID
- ZDB-PUB-010814-4
- Date
- 2001
- Source
- Developmental Dynamics : an official publication of the American Association of Anatomists 221(4): 365-372 (Journal)
- Registered Authors
- Li, Lei
- Keywords
- behavioral visual test; mutation; visual system development; retinal degeneration; olfactoretinal centrifugal pathway; zebrafish
- MeSH Terms
-
- Animals
- Behavior*
- Models, Biological
- Mutation*
- Ocular Physiological Phenomena*
- Vision, Ocular/genetics*
- Vision, Ocular/physiology*
- Zebrafish
- PubMed
- 11500973 Full text @ Dev. Dyn.
Citation
Li, L. (2001) Zebrafish mutants: Behavioral genetic studies of visual system defects. Developmental Dynamics : an official publication of the American Association of Anatomists. 221(4):365-372.
Abstract
Zebrafish are a promising model for behavioral and genetic studies of vertebrate visual system development and retinal degeneration. In the past few years, numerous studies on zebrafish vision have been published. While most of the studies focus on the molecular and cellular characterization of mutations that disrupt zebrafish visual system structure in early development, others examine the mechanisms that underlie inherited visual system disorders in adults. Behavioral assays, along with morphologic and electrophysiological methods, are powerful tools for functional analyses of zebrafish visual development and performance.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping