PUBLICATION
The Tol2 transposable element of the medaka fish: an active DNA-based element naturally occurring in a vertebrate genome
- Authors
- Koga, A. and Hori, H.
- ID
- ZDB-PUB-010718-19
- Date
- 2001
- Source
- Genes & genetic systems 76(1): 1-8 (Review)
- Registered Authors
- Hori, Hiroshi, Koga, Akihiko
- Keywords
- zebrafish Danio rerio, M hybrid dysgenesis, tc1-like transposon, tyrosinase gene, albino mutation, Oryzias latipes, Xenopus laevis, P-element, putative transposase, sleeping-beauty
- MeSH Terms
-
- Animals
- Biological Evolution
- DNA Transposable Elements/genetics*
- Female
- Gene Duplication
- Genetic Techniques
- Genetic Variation
- Genome
- Male
- Oryzias/genetics*
- Transposases/genetics
- Vertebrates/genetics
- PubMed
- 11376546 Full text @ Genes Genet. Sys.
Citation
Koga, A. and Hori, H. (2001) The Tol2 transposable element of the medaka fish: an active DNA-based element naturally occurring in a vertebrate genome. Genes & genetic systems. 76(1):1-8.
Abstract
Several DNA-based transposable elements are known to be present in vertebrate genomes, but few of them have been demonstrated to be active. The Tol2 element of the medaka fish is one such element and, therefore, is potentially useful for developing a gene tagging system and other molecular biological tools applicable to vertebrates. Towards this goal, analyses of the element at the molecular, cellular and population levels are in progress. Results so far obtained are described here.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping