| ZFIN ID: ZDB-PUB-010712-1 |
An ancestral whole-genome duplication may not have been responsible for the abundance of duplicated fish genes
Robinson-Rechavi, M., Marchand, O., Escriva, H., and Laudet, V.
| Date: | 2001 |
|---|---|
| Source: | Current biology : CB 11(12): R458-R459 (Review) |
| Registered Authors: | Escriva, Hector, Laudet, Vincent, Marchand, Oriane, Robinson-Rechavi, Marc |
| Keywords: | none |
| MeSH Terms: |
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| PubMed: | 11448784 Full text @ Curr. Biol. |
Citation
Robinson-Rechavi, M., Marchand, O., Escriva, H., and Laudet, V. (2001) An ancestral whole-genome duplication may not have been responsible for the abundance of duplicated fish genes. Current biology : CB. 11(12):R458-R459.
ABSTRACT
Euteleost fishes have more duplicate genes than mammals [1,2] . The presence of additional Hox clusters in the zebrafish and observation of synteny groups have led to the hypothesis that a whole genome duplication at the origin of actinopterygian fish is responsible for these additional genes [3,4]. The alternative hypothesis ( Fig. 1) is that the abundance of duplicate genes is due to a high rate of local duplications, preceded or not by ancestral tetraploidization and massive gene loss. Our aim is to distinguish between these two hypotheses for the origin of duplicate genes in fish.
ADDITIONAL INFORMATION
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