Pattern formation in the lateral line of zebrafish
- Gompel, N., Cubedo, N., Thisse, C., Thisse, B., Dambly-Chaudiere, C., and Ghysen, A.
- Mechanisms of Development 105(1-2): 69-77 (Journal)
- Registered Authors
- Cubedo, Nicolas, Ghysen, Alain, Gompel, Nicolas, Thisse, Bernard, Thisse, Christine
- vertebrates; zebrafish; lateral line; sensory system; peripheral nervous system; migratory primordium; hair cell; neuromasts; pattern formation
- MeSH Terms
- Cell Lineage
- Cell Movement
- Cell Nucleus/metabolism
- Fluorescent Dyes/pharmacology
- Gene Expression Regulation, Developmental*
- Hair Cells, Auditory/metabolism
- In Situ Hybridization
- Microscopy, Video
- Time Factors
- Ultraviolet Rays
- 11429283 Full text @ Mech. Dev.
Gompel, N., Cubedo, N., Thisse, C., Thisse, B., Dambly-Chaudiere, C., and Ghysen, A. (2001) Pattern formation in the lateral line of zebrafish. Mechanisms of Development. 105(1-2):69-77.
The lateral line of fish and amphibians is a sensory system that comprises a number of individual sense organs, the neuromasts, arranged in a defined pattern on the surface of the body. A conspicuous part of the system is a line of organs that extends along each flank (and which gave the system its name). At the end of zebrafish embryogenesis, this line comprises 7-8 neuromasts regularly spaced between the ear and the tip of the tail. The neuromasts are deposited by a migrating primordium that originates from the otic region. Here, we follow the development of this pattern and show that heterogeneities within the migrating primordium prefigure neuromast formation.
Genes / Markers
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Engineered Foreign Genes