ZFIN ID: ZDB-PUB-010705-16
Pattern formation in the lateral line of zebrafish
Gompel, N., Cubedo, N., Thisse, C., Thisse, B., Dambly-Chaudiere, C., and Ghysen, A.
Date: 2001
Source: Mechanisms of Development 105(1-2): 69-77 (Journal)
Registered Authors: Cubedo, Nicolas, Ghysen, Alain, Gompel, Nicolas, Thisse, Bernard, Thisse, Christine
Keywords: vertebrates; zebrafish; lateral line; sensory system; peripheral nervous system; migratory primordium; hair cell; neuromasts; pattern formation
MeSH Terms:
  • Animals
  • Cell Lineage
  • Cell Movement
  • Cell Nucleus/metabolism
  • Dextrans/pharmacology
  • Fluorescein/pharmacology
  • Fluorescent Dyes/pharmacology
  • Gene Expression Regulation, Developmental*
  • Hair Cells, Auditory/metabolism
  • In Situ Hybridization
  • Microscopy, Video
  • Mitosis
  • Neurons/physiology*
  • Time Factors
  • Ultraviolet Rays
  • Zebrafish
PubMed: 11429283 Full text @ Mech. Dev.
FIGURES
ABSTRACT
The lateral line of fish and amphibians is a sensory system that comprises a number of individual sense organs, the neuromasts, arranged in a defined pattern on the surface of the body. A conspicuous part of the system is a line of organs that extends along each flank (and which gave the system its name). At the end of zebrafish embryogenesis, this line comprises 7-8 neuromasts regularly spaced between the ear and the tip of the tail. The neuromasts are deposited by a migrating primordium that originates from the otic region. Here, we follow the development of this pattern and show that heterogeneities within the migrating primordium prefigure neuromast formation.
ADDITIONAL INFORMATIONNo data available