PUBLICATION
Transcription elongation: The 'Foggy' is lifting ellipsis
- Authors
- Zorio, D.A. and Bentley, D.L.
- ID
- ZDB-PUB-010405-4
- Date
- 2001
- Source
- Current biology : CB 11(4): R144-R146 (Review)
- Registered Authors
- Keywords
- RNA-polymerase-II, P-TEFB, In-vitro, Spt5, protein, complexes, DSIF, activation, invitro, kinase
- MeSH Terms
-
- Chromosomal Proteins, Non-Histone*
- Repressor Proteins*
- Fungal Proteins/genetics
- Fungal Proteins/metabolism*
- Fungal Proteins/physiology
- Transcription Factors/genetics
- Transcription Factors/metabolism*
- Transcription Factors/physiology
- Protein Serine-Threonine Kinases/metabolism
- Nuclear Proteins/genetics
- Nuclear Proteins/metabolism*
- Nuclear Proteins/physiology
- Humans
- Zebrafish Proteins*
- Animals
- Dichlororibofuranosylbenzimidazole
- Positive Transcriptional Elongation Factor B
- Transcriptional Elongation Factors*
- Transcription, Genetic*
- RNA Polymerase II/metabolism
- PubMed
- 11250170 Full text @ Curr. Biol.
Citation
Zorio, D.A. and Bentley, D.L. (2001) Transcription elongation: The 'Foggy' is lifting ellipsis. Current biology : CB. 11(4):R144-R146.
Abstract
Transcription can be controlled by regulating either the initiation or elongation of RNA chains. Recent studies highlight the importance of an elongation regulator, Spt5, in controlling gene expression in yeast, fruit fly and zebrafish; Spt5 may provide a link between transcriptional elongation and cell fate.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping