PUBLICATION
Zebrafish Hsp40 and Hsc70 genes are both induced during caudal fin regeneration
- Authors
- Tawk, M., Joulie, C., and Vriz, S.
- ID
- ZDB-PUB-001205-9
- Date
- 2000
- Source
- Mechanisms of Development 99(1-2): 183-186 (Journal)
- Registered Authors
- Vriz, Sophie
- Keywords
- zebrafish; caudal fin; regeneration; development; Hsp40; wound healing; blastema; chaperones; Hsc70; heat shock proteins; osteoblasts
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Carrier Proteins/biosynthesis*
- Carrier Proteins/genetics*
- DNA, Complementary/metabolism
- Gene Library
- HSC70 Heat-Shock Proteins
- HSP40 Heat-Shock Proteins
- HSP70 Heat-Shock Proteins*
- Heat-Shock Proteins/biosynthesis*
- Heat-Shock Proteins/genetics*
- In Situ Hybridization
- Molecular Sequence Data
- RNA, Messenger/metabolism
- Regeneration
- Sequence Homology, Amino Acid
- Zebrafish/embryology*
- Zebrafish/physiology*
- Zebrafish Proteins
- PubMed
- 11091090 Full text @ Mech. Dev.
Citation
Tawk, M., Joulie, C., and Vriz, S. (2000) Zebrafish Hsp40 and Hsc70 genes are both induced during caudal fin regeneration. Mechanisms of Development. 99(1-2):183-186.
Abstract
We report the characterization of a zebrafish DnaJ-like protein, homologue to the human Hsp40 protein hdj1, that we named zf-Hsp40. We have studied its expression during fin regeneration and we show that zf-Hsp40 mRNA level is drastically increased in all ray segments beneath the regenerated part, or blastema, in response to caudal fin amputation. In order to investigate whether zf-Hsp40 is part of a stress response system after injury, we studied the expression of the zebrafish Hsc70 transcript. Our results show a correlation between the expression of the two transcripts.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping