PUBLICATION

Genetics of heart development

Authors
Chen, J.N. and Fishman, M.C.
ID
ZDB-PUB-001101-8
Date
2000
Source
Trends in genetics : TIG   16(9): 383-388 (Review)
Registered Authors
Chen, Jau-Nian, Fishman, Mark C.
Keywords
none
MeSH Terms
  • Animals
  • Biological Evolution
  • Body Patterning
  • Heart/embryology*
  • Heart/physiology
  • Mice
  • Morphogenesis
PubMed
10973066 Full text @ Trends Genet.
Abstract
The genes that drive heart-cell differentiation in vertebrates and Drosophila are similar, even though the Drosophila 'heart' is a simple tube and the vertebrate heart is a multichambered physiologically complex organ. Mutational analysis in mice and, as particular focus of this review, in zebrafish, reveals the additional genes brought into play to fashion these evolutionarily 'new' organotypic components.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes