PUBLICATION

Sequence, expression, and location of zebrafish frizzled 10

Authors
Nasevicius, A., Hyatt, T.M., Hermanson, S.B., and Ekker, S.C.
ID
ZDB-PUB-000419-1
Date
2000
Source
Mechanisms of Development   92(2): 311-314 (Journal)
Registered Authors
Ekker, Stephen C., Hermanson, Spencer, Hyatt, Tana, Nasevicius, Aidas
Keywords
Wnt; frizzled; tailbud mesenchyme; neural tube; dorsal neural tube; tectum; cerebellum; midbrain-hindbrain boundary; forebrain; hindbrain; maternal; zebrafish
MeSH Terms
  • Amino Acid Sequence
  • Animals
  • Brain/embryology
  • Brain/physiology
  • Chromosome Mapping
  • Embryo, Nonmammalian
  • Frizzled Receptors
  • Gastrula
  • Gene Expression Regulation, Developmental*
  • Head/embryology
  • Molecular Sequence Data
  • Receptors, Cell Surface/genetics
  • Receptors, Cell Surface/metabolism
  • Receptors, G-Protein-Coupled
  • Tail/embryology
  • Tail/physiology
  • Zebrafish/embryology
  • Zebrafish/genetics*
  • Zebrafish Proteins*
PubMed
10727872 Full text @ Mech. Dev.
Abstract
Members of the frizzled gene family encode seven-pass transmembrane proteins that function in the interpretation and reception of Wnt-mediated cell-cell communication events. To investigate frizzled function in early zebrafish development, we isolated the maternally contributed frizzled 10 (fz10) gene and localized it to linkage group 8 using radiation hybrid mapping. The cloned zebrafish fz10 is closely related to the fz10 group from other organisms. Zygotic expression of fz10 is observed in the posterior tail mesenchyme, dorsal neural tube, and different parts of the brain.
Genes / Markers
Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes