Person
            Lyons, Susan
            
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                        Biography and Research Interest
                    
                    
                
                
            
        
        
    
        
            
            
                
I am studying myeloid development using the zebrafish model.  I am currently isolating ENU-mutagenized fish with defects in the myeloid pathway.  As an Oncologist, I have a long-term interest in relating my findings to understanding human leukemia.
            
        
        
    
    
    
                
                    
                        Non-Zebrafish Publications
                    
                    
                
                
            
        
        
    
        
            
            
1.	Stimac, E., Lyons, S. and Pious, D.  Transcription of HLA class II genes in the absence of B-	cell-specific octamer binding factor.  Mol Cell Biol  8:3734-3739, 1988.2. Nichols, W.C., Lyons, S.E., Harrison, J.S., Cody, R.L. and Ginsburg, D. Severe von Willebrand disease due to a defect at the level of von Willebrand factor mRNA expression: Detection by exonic PCR-restriction fragment length polymorphism analysis. Proc Natl Acad Sci USA 88:3857-3861, 1991.
3. Lyons, S.E., Bruck, M.E., Bowie, E.J.W., and Ginsburg, D. Impaired intracellular transport produced by a subset of type IIA von Willebrand disease mutations. J Biol Chem 267:4424-4430, 1992.
4. Cooney, K.A., Lyons, S.E., and Ginsburg, D. Functional analysis of a type IIB von Willebrand disease missense mutation: Increased binding of large von Willebrand factor multimers to platelets. Proc Natl Acad Sci USA 89:2869-2872, 1992.
5. Lyons, S.E. and Ginsburg, D. Molecular and cellular biology of von Willebrand factor. Trends in Cardiovascular Medicine 4:34-39, 1994.
6. Lyons, S.E., Cooney, K.A., Bockenstedt, P., and Ginsburg, D. Characterization of Leu777Pro and Ile865Thr type IIA von Willebrand disease mutations. Blood 83:1551- 1557, 1994.
7. Lyons, S.E. and Liebowitz, D. The roles of human viruses in the pathogenesis of lymphoma. Semin Oncol. 25(4):461-75, 1998.