ZFIN ID: ZDB-PERS-981215-4
Pogoda, Hans-Martin
Email: pogodah@uni-koeln.de
URL:
Affiliation: Hammerschmidt Lab
Address: Institute for Zoology Division of Developmental Biology Cologne University Biocenter Zuelpicher Strasse 47b Cologne, D-50674 Germany
Country: Germany
Phone: +49-(0)221-4702738
Fax: +49-(0)221-4705164
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS
* Studies of biology at the University of Freiburg (Germany) with emphasis on developmental biology, genetics and zoological systematics (1993-1999)
* Diploma thesis on smad genes in zebrafish early patterning (1999), Freiburg
* Graduate student with Dirk Meyer at University of Freiburg pursuing my studies on the intra-cellular TGFß signal transduction via Smads and FoxH1 in zebrafish
* Ph.D. received in July 2002
* Postdoc with William S. Talbot at Stanford School of Medicine (2002-2004) conducting a genetic screen for mutations that disrupt myelination
* Postdoc with Matthias Hammerschmidt at the Max-Planck-Institute of Immunology (Freiburg) working on pituitary gland development in zebrafish (2004-2008)
* Tenured senior scientist in the lab of Matthias Hammerschmidt at Cologne University since 2008 pursuing my studies on the endocrine system plus embarking on the development of the zebrafish skeleton

My current research aims to decipher the cellular and molecular machinery that constructs and maintains the segmented backbone in teleosts using the zebrafish as a model.


PUBLICATIONS
Pogoda, H.M., Riedl-Quinkertz, I., Hammerschmidt, M. (2023) Direct BMP signaling to chordoblasts is required for the initiation of segmented notochord sheath mineralization in zebrafish vertebral column development. Frontiers in endocrinology. 14:11073391107339
Zhang, J.L., Richetti, S., Ramezani, T., Welcker, D., Lütke, S., Pogoda, H.M., Hatzold, J., Zaucke, F., Keene, D.R., Bloch, W., Sengle, G., Hammerschmidt, M. (2022) Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2. Matrix biology : journal of the International Society for Matrix Biology. 112:132-154
Hatzold, J., Wessendorf, H., Pogoda, H.M., Bloch, W., Hammerschmidt, M. (2021) The Kunitz-type serine protease inhibitor Spint2 is required for cellular cohesion, coordinated cell migration and cell survival during zebrafish hatching gland development. Developmental Biology. 476:148-170
Jurkute, N., Leu, C., Pogoda, H.M., Arno, G., Robson, A.G., Nürnberg, G., Altmüller, J., Thiele, H., Motameny, S., Toliat, M.R., Powell, K., Höhne, W., Michaelides, M., Webster, A.R., Moore, A.T., Hammerschmidt, M., Nürnberg, P., Yu-Wai-Man, P., Votruba, M. (2019) SSBP1 mutations in dominant optic atrophy with variable retinal degeneration. Annals of neurology. 86(3):368-383
Pogoda, H.M., Riedl-Quinkertz, I., Löhr, H., Waxman, J.S., Dale, R.M., Topczewski, J., Schulte-Merker, S., Hammerschmidt, M. (2018) Direct activation of chordoblasts by retinoic acid is required for segmented centra mineralization during zebrafish spine development. Development (Cambridge, England). 145(9)
Liu, F., Pogoda, H.M., Pearson, C.A., Ohyama, K., Löhr, H., Hammerschmidt, M., and Placzek, M. (2013) Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis. Development (Cambridge, England). 140(5):1111-1122
Laue, K., Pogoda, H.M., Daniel, P.B., van Haeringen, A., Alanay, Y., von Ameln, S., Rachwalski, M., Morgan, T., Gray, M.J., Breuning, M.H., Sawyer, G.M., Sutherland-Smith, A.J., Nikkels, P.G., Kubisch, C., Bloch, W., Wollnik, B, Hammerschmidt, M., and Robertson, S.P. (2011) Craniosynostosis and Multiple Skeletal Anomalies in Humans and Zebrafish Result from a Defect in the Localized Degradation of Retinoic Acid. American journal of human genetics. 89(5):595-606
Clark, K.J., Balciunas, D., Pogoda, H.M., Ding, Y., Westcot, S.E., Bedell, V.M., Greenwood, T.M., Urban, M.D., Skuster, K.J., Petzold, A.M., Ni, J., Nielsen, A.L., Patowary, A., Scaria, V., Sivasubbu, S., Xu, X., Hammerschmidt, M., and Ekker, S.C. (2011) In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Nature Methods. 8(6):506-512
Pogoda, H.M., and Hammerschmidt, M. (2009) How to make a teleost adenohypophysis: Molecular pathways of pituitary development in zebrafish. Molecular and Cellular Endocrinology. 312(1-2):2-13
Kleinridders, A., Pogoda, H.M., Irlenbusch, S., Smyth, N., Koncz, C., Hammerschmidt, M., and Brüning, J.C. (2009) PLRG1 is an Essential Regulator of Cell Proliferation and Apoptosis during Vertebrate Development and Tissue Homeostasis. Molecular and cellular biology. 29(11):3173-3185
Pogoda, H.M., and Hammerschmidt, M. (2007) Molecular genetics of pituitary development in zebrafish. Seminars in cell & developmental biology. 18(4):543-558
Schweitzer, J., Gimnopoulos, D., Lieberoth, B.C., Pogoda, H.M., Feldner, J., Ebert, A., Schachner, M., Becker, T., and Becker, C.G. (2007) Contactin1a expression is associated with oligodendrocyte differentiation and axonal regeneration in the central nervous system of zebrafish. Molecular and cellular neurosciences. 35(2):194-207
Hirschner, W., Pogoda, H.M., Kramer, C., Thiess, U., Hamprecht, B., Wiesmuller, K.H., Lautner, M., and Verleysdonk, S. (2007) Biosynthesis of Wdr16, a marker protein for kinocilia-bearing cells, starts at the time of kinocilia formation in rat, and wdr16 gene knockdown causes hydrocephalus in zebrafish. Journal of neurochemistry. 101(1):274-288
Pogoda, H.M., Sternheim, N., Lyons, D.A., Diamond, B., Hawkins, T.A., Woods, I.G., Bhatt, D.H., Franzini-Armstrong, C., Dominguez, C., Arana, N., Jacobs, J., Nix, R., Fetcho, J.R., and Talbot, W.S. (2006) A genetic screen identifies genes essential for development of myelinated axons in zebrafish. Developmental Biology. 298(1):118-131
Woods, I.G., Lyons, D.A., Voas, M.G., Pogoda, H.M., and Talbot, W.S. (2006) nsf Is Essential for Organization of Myelinated Axons in Zebrafish. Current biology : CB. 16(7):636-648
Pogoda, H.M., von der Hardt, S., Herzog, W., Kramer, C., Schwarz, H., and Hammerschmidt, M. (2006) The proneural gene ascl1a is required for endocrine differentiation and cell survival in the zebrafish adenohypophysis. Development (Cambridge, England). 133(6):1079-1089
Diekmann, H., Klinger, M., Oertle, T., Heinz, D., Pogoda, H.M., Schwab, M.E., and Stuermer, C.A. (2005) Analysis of the Reticulon Gene Family Demonstrates the Absence of the Neurite Growth Inhibitor Nogo-A in Fish. Mol. Biol. Evol.. 22(8):1635-1648
Lyons, D.A., Pogoda, H.M., Voas, M.G., Woods, I.G., Diamond, B., Nix, R., Arana, N., Jacobs, J., and Talbot, W.S. (2005) erbb3 and erbb2 Are Essential for Schwann Cell Migration and Myelination in Zebrafish. Current biology : CB. 15(6):513-524
Norton, W.H., Mangoli, M., Lele, Z., Pogoda, H.M., Diamond, B., Mercurio, S., Russell, C., Teraoka, H., Stickney, H.L., Rauch, G.J., Heisenberg, C.P., Houart, C., Schilling, T.F., Frohnhoefer, H.G., Rastegar, S., Neumann, C.J., Gardiner, R.M., Strähle, U., Geisler, R., Rees, M., Talbot, W.S., and Wilson, S.W. (2005) Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones. Development (Cambridge, England). 132(4):645-658
Pogoda, H.M. and Meyer, D. (2002) Zebrafish smad7 is regulated by Smad3 and BMP signals. Developmental Dynamics : an official publication of the American Association of Anatomists. 224(3):334-349
Pogoda, H.M., Solnica-Krezel, L., Driever, W., and Meyer, D. (2000) The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of Nodal signaling required for organizer formation. Current biology : CB. 10(17):1041-1049

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