ZFIN ID: ZDB-PERS-980522-1
Biemar, Frédéric
Email: fbiemar@gmail.com
URL: http://www.temple.edu/biology/faculty/biemar.html
Affiliation: Biemar Lab
Address: Adjunct Assistant Professor Department of Biology Temple University 436 Biology Life Sciences Building 1900 North 12th Street Philadelphia PA 19122 USA
Country: United States
Phone: 215-204-0291
Fax: 215-204-6646
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS
We study the gene regulatory network regulating pancreas formation and endocrine cell differentiation.


PUBLICATIONS
Balciuniene, J., Nagelberg, D., Walsh, K., Camerota, D., Georlette, D., Biemar, F., Bellipanni, G., and Balciunas, D. (2013) Efficient disruption of Zebrafish genes using a Gal4-containing gene trap. BMC Genomics. 14(1):619
Verbruggen, V., Ek, O., Georlette, D., Delporte, F., Von Berg, V., Detry, N., Biemar, F., Coutinho, P., Martial, J.A., Voz, M.L., Manfroid, I., and Peers, B. (2010) The Pax6b homeodomain is dispensable for pancreatic endocrine cell differentiation in zebrafish. The Journal of biological chemistry. 285(18):13863-13873
Delporte, F.M., Pasque, V., Devos, N., Manfroid, I., Voz, M.L., Motte, P., Biemar, F., Martial, J.A., and Peers, B. (2008) Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factors. BMC Developmental Biology. 8:53
Zecchin, E., Filippi, A., Biemar, F., Tiso, N., Pauls, S., Ellertsdottir, E., Gnugge, L., Bortolussi, M., Driever, W., and Argenton, F. (2007) Distinct delta and jagged genes control sequential segregation of pancreatic cell types from precursor pools in zebrafish. Developmental Biology. 301(1):192-204
Ellertsdottir, E., Ganz, J., Durr, K., Loges, N., Biemar, F., Seifert, F., Ettl, A.K., Kramer-Zucker, A.K., Nitschke, R., and Driever, W. (2006) A mutation in the zebrafish Na,K-ATPase subunit atp1a1a.1 provides genetic evidence that the sodium potassium pump contributes to left-right asymmetry downstream or in parallel to nodal flow. Developmental dynamics : an official publication of the American Association of Anatomists. 235(7):1794-1808
Mavropoulos, A., Devos, N., Biemar, F., Zecchin, E., Argenton, F., Edlund, H., Motte, P., Martial, J.A., and Peers, B. (2005) sox4b is a key player of pancreatic alpha cell differentiation in zebrafish. Developmental Biology. 285(1):211-223
de Cat, B., Muyldermans, S.Y., Coomans, C., Degeest, G., Vanderschueren, B., Creemers, J., Biemar, F., Peers, B., and David, G. (2003) Processing by proprotein convertases is required for glypican-3 modulation of cell survival, Wnt signaling, and gastrulation movements. The Journal of cell biology. 163(3):625-635
Biemar, F., Baraldi, F., Devos, N., Holzschuh, J., Martial, J.A., Driever, W., and Peers, B. (2002) Analysis of meis genes expression in zebrafish suggests a role in the development of organs derived from the endoderm. Developmental Biology. 247(2):495
Devos, N., Deflorian, G., Biemar, F., Bortolussi, M., Martial, J.A., Peers, B., and Argenton, F. (2002) Differential expression of two somatostatin genes during zebrafish embryonic development. Mechanisms of Development. 115(1-2):133-137
Biemar, F., Devos, N., Martial, J.A., Driever, W., and Peers, B. (2001) Cloning and expression of the TALE superclass homeobox Meis2 gene during zebrafish embryonic development. Mechanisms of Development. 109(2):427-431
Molina, A., Iyengar, A., Marins, L.F., Biemar, F., Hanley, S., Maclean, N., Smith, T.J., Martial, J.A., and Muller, M. (2001) Gene structure and promoter function of a teleost ribosomal protein: a tilapia (Oreochromis mossambicus) L18 gene. BBA Gene Structure and Expression. 1520(3):195-202
Biemar, F., Argenton, F., Schmidtke, R., Epperlein, S., Peers, B., and Driever, W. (2001) Pancreas development in zebrafish: early dispersed appearance of endocrine hormone expressing cells and their convergence to form the definitive islet. Developmental Biology. 230(2):189-203
Molina, A., Biemar, F., Müller, F., Iyengar, A., Prunet, P., Maclean, N., Martial, J.A., and Muller, M. (2000) Cloning and expression analysis of an inducible HSP70 gene from tilapia fish. FEBS letters. 474(1):5-10

NON-ZEBRAFISH PUBLICATIONS
Manak JR, Dike S, Sementchenko V, Kapranov P, Biemar F, Long J, Cheng J, Bell I, Ghosh S, Piccolboni A, Gingeras TR. Biological function of unannotated transcription during the early development of Drosophila melanogaster. Nat Genet. (2006) 10:1151-8.

Biemar F, Nix DA, Piel J, Peterson B, Ronshaugen M, Sementchenko V, Bell I, Manak JR, Levine MS. Comprehensive identification of Drosophila dorsal-ventral patterning genes using a whole-genome tiling array. Proc Natl Acad Sci U S A. (2006) 103:12763-8.

Ronshaugen M, Biemar F, Piel J, Levine M, Lai EC. The Drosophila microRNA iab-4 causes a dominant homeotic transformation of halteres to wings. Genes Dev. (2005) 19:2947-52.

Biemar F, Zinzen R, Ronshaugen M, Sementchenko V, Manak JR, Levine MS. Spatial regulation of microRNA gene expression in the Drosophila embryo. Proc Natl Acad Sci U S A. (2005) 102:15907-11.