Person
Lekven, Arne
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Biography and Research Interest
The research focus of my lab is to investigate the role of the Wnt signaling pathway during embryogenesis. We are using a combination of genetic loss-of-function and morpholino knockdown approaches to understand how wnt ligands pattern embryonic tissues.
Non-Zebrafish Publications
Haag TA, Haag NP, Lekven AC, Hartenstein V. The role of cell adhesion molecules in drosophila heart morphogenesis: faint sausage, Shotgun/DE-cadherin, and laminin A are required for discrete stages in heart development. Dev Biol 1999 Apr 1;208(1):56-69Hartenstein V, Nassif C, Lekven A. Embryonic development of the Drosophila brain. II. Pattern of glial cells. J Comp Neurol 1998 Dec 7;402(1):32-47
Lekven AC, Tepass U, Keshmeshian M, Hartenstein V. faint sausage encodes a novel extracellular protein of the immunoglobulin
superfamily required for cell migration and the establishment of normal axonal pathways in the Drosophila nervous system.
Development 1998 Jul;125(14):2747-58
Hartenstein V, Younossi-Hartenstein A, Lekven A.
Delamination and division in the Drosophila neurectoderm: spatiotemporal pattern, cytoskeletal dynamics, and common control by neurogenic and segment polarity genes.
Dev Biol 1994 Oct;165(2):480-99