Person
Kane, Andrew S.
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Biography and Research Interest
Dr. Kane studies pathology and toxicology of aquatic and marine organisms with emphasis on Chesapeake Bay fauna, and aquaculture and captive fish species. The pathology of fish, amphibians and other aquatic organisms is studied to better understand disease processes and the effects of environmental stressors (e.g., PAHs, PCBs, metals, suboptimal water quality, toxic and bioactive substances, and parasitism). Dr. Kane’s toxicology studies include examining alterations in behavior and phase I-phase II biotransformation pathways due to environmental stressors. Subtle behavioral alterations serve as endpoints using computer-based video movement analysis of sublethally-exposed organisms. Biotransformation studies are carried out with liver and gill microsomal preparations, as well as tissue explants and precision-cut liver slices. Further studies include the examination of subtle, sexually dimorphic alterations in neuronal microanatomy that may serve as a bioindicator of exposure to endocrine disrupting compounds in the environment. Dr. Kane also focuses on science communication and outreach, and applies interactive, computer-based multimedia and worldwide technology as dynamic teaching and learning tools.
Non-Zebrafish Publications
Kane, A.S. 1995. Multimedia as a training tool for fish anatomy and necropsy. Lab Animal. 47:48-50.Kane, A.S. 1995. Multimedia update: Advances in computer-based applications relevant to fish and fish health. Annual Review of Fish Disease. 5:79-84.
Kane, A.S., J.F. González and R. Reimschuessel. 1996. Fish and amphibian models used in toxicology. Lab Animal. 25(6):33-38.
Kane, A.S. and R. Reimschuessel. 1996. FishGuts: A Multimedia Guide to the Art and Science of Fish Necropsy. Ed. A.S. Kane, APC Press, University of Maryland at Baltimore, Baltimore, MD. (http://som1.umaryland.edu/aquaticpath/fg)
Kane, A.S. and S. Thohan. 1996. Use of fish hepatic tissue slices to evaluate alterations due to environmental exposure. Pages 371-391 in: G. Ostrander, editor. Methods in Aquatic Toxicology. Lewis Publishers, Boca Raton, FL.
Kane, A.S., S.V. Jacobson and R. Reimschuessel. 1996. Construction and use of a large scale dosing system to expose fish to waterborne toxicants. Pages 589-607 in: G. Ostrander, editor. Methods in Aquatic Toxicology. Lewis Publishers, Boca Raton, FL.
Kane, A.S., D. Oldach and R. Reimschuessel. 1998. Fish Lesions in Chesapeake Bay: Pfiesteria-like Dinoflagellates and Other Etiologies. Maryland Medical Journal, 47(3):106-112.
Yonkos, L.T. and A.S. Kane. 1999. Development of a digital atlas of fathead minnow histology. Lab Animal. 28(2):39-42 (content on the web at http://som1.umaryland.edu/aquaticpath/fhm).
Kane, A.S., A. Baya, R. Reimschuessel, K.M. St. Pe, C.A. Poukish and C.P. Driscoll. 1999. Field sampling and necropsy examination of fish. Virginia Journal of Science 50(4):345-364.
Dykstra, M.J. and A.S. Kane. 2000. Pfiesteria piscicida and ulcerative mycosis of Atlantic menhaden; current status of understanding. Journal of Aquatic Animal Health 12:18-25.