ZFIN ID: ZDB-PERS-960805-536
Stock, David W.
Email: david.stock@colorado.edu
URL: http://www.colorado.edu/epob/research/fac_stock.html
Affiliation: Stock Lab
Address: Department of Environmental, Population and Organismic Biology University of Colorado Campus Box 334 Boulder, CO 80309-0334 USA
Country: United States
Phone: (303) 735-1746
Fax: (303) 492-8699

I am interested in the developmental genetic basis of morphological evolution and am using the vertebrate dentition as a model system for investigating this. Specifically I am interested in evolutionary changes in tooth location, number, and shape. I am investigating the genetic control of tooth development in the zebrafish and several other species of teleost fishes.

Aigler, S.R., Jandzik, D., Hatta, K., Uesugi, K., Stock, D.W. (2014) Selection and constraint underlie irreversibility of tooth loss in cypriniform fishes. Proceedings of the National Academy of Sciences of the United States of America. 111(21):7707-12
Jackman, W.R., Davies, S.H., Lyons, D.B., Stauder, C.K., Denton-Schneider, B.R., Jowdry, A., Aigler, S.R., Vogel, S.A., Stock, D.W. (2013) Manipulation of Fgf and Bmp signaling in teleost fishes suggests potential pathways for the evolutionary origin of multicuspid teeth. Evolution & development. 15:107-18
Jackman, W.R., Yoo, J.J., and Stock, D.W. (2010) Hedgehog signaling is required at multiple stages of zebrafish tooth development. BMC Developmental Biology. 10:119
Wise, S.B., and Stock, D.W. (2010) bmp2b and bmp4 are dispensable for zebrafish tooth development. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(10):2534-2546
Gibert, Y., Bernard, L., Debiais-Thibaud, M., Bourrat, F., Joly, J.S., Pottin, K., Meyer, A., Retaux, S., Stock, D.W., Jackman, W.R., Seritrakul, P., Begemann, G., and Laudet, V. (2010) Formation of oral and pharyngeal dentition in teleosts depends on differential recruitment of retinoic acid signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24(9):3298-3309
Stock, D.W. (2007) Zebrafish dentition in comparative context. The Journal of experimental biology. 308(5):523-549
Jackman, W.R., and Stock, D.W. (2006) Transgenic analysis of Dlx regulation in fish tooth development reveals evolutionary retention of enhancer function despite organ loss. Proceedings of the National Academy of Sciences of the United States of America. 103(51):19390-19395
Wise, S.B., and Stock, D.W. (2006) Conservation and divergence of Bmp2a, Bmp2b, and Bmp4 expression patterns within and between dentitions of teleost fishes. Evolution & development. 8(6):511-523
Stock, D.W., Jackman, W.R., and Trapani, J. (2006) Developmental genetic mechanisms of evolutionary tooth loss in cypriniform fishes. Development (Cambridge, England). 133(16):3127-3137
Walker, M.B., Miller, C.T., Talbot, J.C., Stock, D.W., and Kimmel, C.B. (2006) Zebrafish furin mutants reveal intricacies in regulating Endothelin1 signaling in craniofacial patterning. Developmental Biology. 295(1):194-205
Borday-Birraux, V., Van der Heyden, C., Debiais-Thibaud, M., Verreijdt, L., Stock, D.W., Huysseune, A., and Sire, J.Y. (2006) Expression of Dlx genes during the development of the zebrafish pharyngeal dentition: evolutionary implications. Evolution & development. 8(2):130-141
Jackman, W.R., Draper, B.W., and Stock, D.W. (2004) Fgf signaling is required for zebrafish tooth development. Developmental Biology. 274(1):139-157
Draper, B.W., Stock, D.W., and Kimmel, C.B. (2003) Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development. Development (Cambridge, England). 130(19):4639-4654
Draper, B. W., Phillips, J.B., Stock, D.W., and Kimmel, C.B. (1999) FGF signaling and mesodermal patterning in the zebrafish embryo. Developmental Biology. 210(1):151-180
Ellies, D.L., D.W. Stock, G. Hatch, G. Giroux, K.M. Weiss, and M. Ekker (1997) Relationship between the genomic organization and the overlapping embryonic expression patterns of the zebrafish dlx genes. Genomics. 45(3):580-590
Stock, D.W., Ellies, D.L., Zhao, Z.Y., Ekker, M., Ruddle, F.H., and Weiss, K.M. (1996) The evolution of the vertebrate Dlx gene family. Proceedings of the National Academy of Sciences of the United States of America. 93(20):10858-10863