ZFIN Person: Cordero-Maldonado, Maria Lorena

ZFIN ID: ZDB-PERS-210419-2

Cordero-Maldonado, Maria Lorena

Email:	marialorena.corderomaldonado@uni.lu
URL:	https://wwwen.uni.lu/lcsb
Affiliation:
Address:	University of Luxembourg Luxembourg Centre For Systems Biomedicine (LCSB) Campus Belval 6, avenue du Swing L-4367 Belvaux
Country:	Luxembourg
Phone:	+352 466644 6424
Fax:
ORCID ID:	0000-0001-5631-0022

BIOGRAPHY AND RESEARCH INTERESTS

Disease modeling
Rare diseases
Neurological disorders
Drug screens

PUBLICATIONS

Heins-Marroquin, U., Singh, R.R., Perathoner, S., Gavotto, F., Merino Ruiz, C., Patraskaki, M., Gomez-Giro, G., Kleine Borgmann, F., Meyer, M., Carpentier, A., Warmoes, M.O., Jäger, C., Mittelbronn, M., Schwamborn, J.C., Cordero-Maldonado, M.L., Crawford, A.D., Schymanski, E.L., Linster, C.L. (2024) CLN3 deficiency leads to neurological and metabolic perturbations during early development. Life science alliance. 7(3):

Martins, T.G., Soliman, R., Cordero-Maldonado, M.L., Donato, C., Ameli, C., Mombaerts, L., Skupin, A., Peri, F., Crawford, A.D. (2023) Seizure-induced increase in microglial cell population in the developing zebrafish brain. Epilepsy Research. 195:107203107203

Mhlongo, F., Cordero-Maldonado, M.L., Crawford, A.D., Katerere, D., Sandasi, M., Hattingh, A.C., Koekemoer, T.C., van de Venter, M., Viljoen, A.M. (2021) Evaluation of the wound healing properties of South African medicinal plants using zebrafish and in vitro bioassays. Journal of ethnopharmacology. 286:114867

Chipiti, T., Viljoen, A.M., Cordero-Maldonado, M.L., Veale, C.G.L., Van Heerden, F.R., Sandasi, M., Chen, W., Crawford, A.D., Enslin, G.M. (2021) Anti-seizure activity of African medicinal plants: the identification of bioactive alkaloids from the stem bark of Rauvolfia caffra using an in vivo zebrafish model. Journal of ethnopharmacology. 279:114282

Soliman, R., Cordero-Maldonado, M.L., Martins, T.G., Moein, M., Conrotte, J.F., Warmack, R.A., Skupin, A., Crawford, A.D., Clarke, S.G., Linster, C.L. (2021) l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain. Frontiers in genetics. 11:612343

Tiraboschi, E., Martina, S., van der Ent, W., Grzyb, K., Gawel, K., Cordero-Maldonado, M.L., Poovathingal, S.K., Heintz, S., Satheesh, S.V., Brattespe, J., Xu, J., Suster, M., Skupin, A., Esguerra, C.V. (2020) New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome. Epilepsia. 61(3):549-560

Heins-Marroquin, U., Jung, P.P., Cordero-Maldonado, M.L., Crawford, A.D., Linster, C.L. (2019) Phenotypic assays in yeast and zebrafish reveal drugs that rescue ATP13A2 deficiency. Brain communications. 1:fcz019

Cordero-Maldonado, M.L., Perathoner, S., van der Kolk, K.J., Boland, R., Heins-Marroquin, U., Spaink, H.P., Meijer, A.H., Crawford, A.D., de Sonneville, J. (2019) Deep learning image recognition enables efficient genome editing in zebrafish by automated injections. PLoS One. 14:e0202377

Siverio-Mota, D., Andujar, I., Marrero-Ponce, Y., Giner, R.M., Mendoza, C.D., Paba, G.M., Vicet-Muro, L., Cordero-Maldonado, M.L., de Witte, P.A.M., Crawford, A.D., Veitia, M.S., Perez-Jimenez, F., Aran, V.J. (2018) Anti-Inflammatory Activity and Cheminformatics Analysis of New Potent 2-Substituted 1-Methyl-5-Nitroindazolinones. Current topics in medicinal chemistry. 17(30):3236-3248

Köglsberger, S., Cordero-Maldonado, M.L., Antony, P., Forster, J.I., Garcia, P., Buttini, M., Crawford, A., Glaab, E. (2017) Gender-Specific Expression of Ubiquitin-Specific Peptidase 9 Modulates Tau Expression and Phosphorylation: Possible Implications for Tauopathies. Molecular neurobiology. 54(10):7979-7993

Perathoner, S., Cordero-Maldonado, M.L., Crawford, A.D. (2016) Potential of zebrafish as a model for exploring the role of the amygdala in emotional memory and motivational behavior. Journal of neuroscience research. 94(6):445-62

Galizia, E.C., Myers, C.T., Leu, C., de Kovel, C.G., Afrikanova, T., Cordero-Maldonado, M.L., Martins, T.G., Jacmin, M., Drury, S., Krishna Chinthapalli, V., Muhle, H., Pendziwiat, M., Sander, T., Ruppert, A.K., Møller, R.S., Thiele, H., Krause, R., Schubert, J., Lehesjoki, A.E., Nürnberg, P., Lerche, H., EuroEPINOMICS CoGIE Consortium, Palotie, A., Coppola, A., Striano, S., Gaudio, L.D., Boustred, C., Schneider, A.L., Lench, N., Jocic-Jakubi, B., Covanis, A., Capovilla, G., Veggotti, P., Piccioli, M., Parisi, P., Cantonetti, L., Sadleir, L.G., Mullen, S.A., Berkovic, S.F., Stephani, U., Helbig, I., Crawford, A.D., Esguerra, C.V., Kasteleijn-Nolst Trenité, D.G., Koeleman, B.P., Mefford, H.C., Scheffer, I.E., Sisodiya, S.M. (2015) CHD2 variants are a risk factor for photosensitivity in epilepsy. Brain : a journal of neurology. 138(Pt 5):1198-207

Siverio-Mota, D., Andujar, I., Marrero-Ponce, Y., Giner, R.M., Vicet-Muro, L., Cordero-Maldonado, M.L., de Witte, P.A., Crawford, A.D., Veitía, M.S., Pérez-Jiménez, F., Aran, V.J. (2014) Pharmacological Evaluation of the Anti-Inflammatory Activity and Chemoinformatic Analysis of New Potent 2-Substituted 1-Methyl-5-Nitroindazolinones. Current topics in medicinal chemistry. 14(999)

Carballeira, N.M., Bwalya, A.G., Itoe, M.A., Andricopulo, A.D., Cordero-Maldonado, M.L., Kaiser, M., Mota, M.M., Crawford, A.D., Guido, R.V., Tasdemir, D. (2014) 2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes. Bioorganic & medicinal chemistry letters. 24(17):4151-7

Gebruers, E., Cordero-Maldonado, M.L., Gray, A.I., Clements, C., Harvey, A.L., Edrada-Ebel, R., de Witte, P.A., Crawford, A.D., and Esguerra, C.V. (2013) A Phenotypic Screen in Zebrafish Identifies a Novel Small-Molecule Inducer of Ectopic Tail Formation Suggestive of Alterations in Non-Canonical Wnt/PCP Signaling. PLoS One. 8(12):e83293

Cordero-Maldonado, M.L., Siverio-Mota, D., Vicet-Muro, L., Wilches-Arizábala, I.M., Esguerra, C.V., de Witte, P.A., and Crawford, A.D. (2013) Optimization and pharmacological validation of a leukocyte migration assay in zebrafish larvae for the rapid in vivo bioactivity analysis of anti-inflammatory secondary metabolites. PLoS One. 8(10):e75404

Bohni, N., Cordero-Maldonado, M.L., Maes, J., Siverio-Mota, D., Marcourt, L., Munck, S., Kamuhabwa, A.R., Moshi, M.J., Esguerra, C.V., de Witte, P.A., Crawford, A.D., and Wolfender, J.L. (2013) Integration of Microfractionation, qNMR and Zebrafish Screening for the In Vivo Bioassay-Guided Isolation and Quantitative Bioactivity Analysis of Natural Products. PLoS One. 8(5):e64006

Marrero-Ponce, Y., Siverio-Mota, D., Gálvez-Llompart, M., Recio, M.C., Giner, R.M., García-Domènech, R., Torrens, F., Arán, V.J., Cordero-Maldonado, M.L., Esguera, C.V., de Witte, P.A., and Crawford, A.D. (2011) Discovery of novel anti-inflammatory drug-like compounds by aligning in silico and in vivo screening: The nitroindazolinone chemotype. European Journal of Medicinal Chemistry. 46(12):5736-53

NON-ZEBRAFISH PUBLICATIONS