ZFIN ID: ZDB-PERS-170214-9
Aye, Yimon
Email: yimon.aye@epfl.ch
URL: https://leago.epfl.ch/
Affiliation: Aye Lab
Address: EPFL - SB - ISCIC - LEAGO CH A2 397 Station 6 1015 Lausanne


Huang, K.T., Ly, P., Poganik, J.R., Parvez, S., Long, M.J.C., Aye, Y. (2023) Monitoring On-Target Signaling Responses in Larval Zebrafish - Z-REX Unmasks Precise Mechanisms of Electrophilic Drugs and Metabolites. Journal of visualized experiments : JoVE. (196):
Huang, K.T., Poganik, J.R., Parvez, S., Raja, S., Miller, B., Long, M.J.C., Fetcho, J.R., Aye, Y. (2023) Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish. Nature Protocols. 18(5):1379-1415
Van Hall-Beauvais, A., Poganik, J.R., Huang, K.T., Parvez, S., Zhao, Y., Lin, H.Y., Liu, X., Long, M.J.C., Aye, Y. (2022) Z-REX uncovers a bifurcation in function of Keap1 paralogs. eLIFE. 11:
Poganik, J.R., Huang, K.T., Parvez, S., Zhao, Y., Raja, S., Long, M.J.C., Aye, Y. (2021) Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera. Nature communications. 12:5736
Long, M.J.C., Rogg, C., Aye, Y. (2020) An Oculus to Profile and Probe Target Engagement In Vivo: How T-REX Was Born and Its Evolution into G-REX. Accounts of chemical research. 54(3):618-631
Poganik, J.R., Long, M.J.C., Disare, M.T., Liu, X., Chang, S.H., Hla, T., Aye, Y. (2019) Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(12):14636-14652
Surya, S.L., Long, M.J.C., Urul, D.A., Zhao, Y., Mercer, E.J., Elsaid, I.M., Evans, T., Aye, Y. (2018) Cardiovascular small heat shock protein HSPB7 is a kinetically-privileged RES sensor. ACS Chemical Biology. 13(7):1824-1831
Long, M.J., Parvez, S., Zhao, Y., Surya, S.L., Wang, Y., Zhang, S., Aye, Y. (2017) Akt3 is a privileged first responder in isozyme-specific electrophile response. Nature Chemical Biology. 13(3):333-338