ZFIN Person: Chen, Liangbiao

ZFIN ID: ZDB-PERS-170208-24

ZFIN ID: ZDB-PERS-170208-24

Chen, Liangbiao

Email:	lbchen@shou.edu.cn
URL:
Affiliation:	Liangbiao Chen Lab
Address:	Laboratory of Genetic Resources for Aquacultural, Shanghai Ocean University, 999 Hucheng Huan Road, Liangang New City, Pudong District, Shanghai, 201306, China
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ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

Comparative genomics, thermal adaptation, developmental biology

PUBLICATIONS

Li, W., Bu, M., Hu, R., Jiang, S., Chen, L., Somero, G.N. (2023) Tissue-specific temperature dependence of RNA editing levels in zebrafish. BMC Biology. 21:262262

Yueyue, F., Qin, W., Jigang, L., Ouyang, L., Hu, Q., Chen, L. (2023) New insights into the antimicrobial mechanism of LEAP2 mutant zebrafish under Aeromonas hydrophila infection using transcriptome analysis. Fish & shellfish immunology. 143:109225

Fei, Y., Wang, Q., Lu, J., Ouyang, L., Li, W., Hu, R., Chen, L. (2023) Identification of antibacterial activity of LEAP2 from Antarctic icefish Chionodraco hamatus. Journal of fish diseases. 46(9):905-916

Zhou, W., Shi, W., Du, X., Han, Y., Tang, Y., Ri, S., Ju, K., Kim, T., Huang, L., Zhang, W., Yu, Y., Tian, D., Yu, Y., Chen, L., Wu, Z., Liu, G. (2023) Assessment of Nonalcoholic Fatty Liver Disease Symptoms and Gut-Liver Axis Status in Zebrafish after Exposure to Polystyrene Microplastics and Oxytetracycline, Alone and in Combination. Environmental health perspectives. 131:4700647006

Wang, Y., Wang, H.M., Zhou, Y., Hu, L.H., Wan, J.M., Yang, J.H., Niu, H.B., Hong, X.P., Hu, P., Chen, L.B. (2023) Dusp1 regulates thermal tolerance limits in zebrafish by maintaining mitochondrial integrity. Zoological research. 44:126141126-141

Hu, R., Li, G., Xu, Q., Chen, L. (2022) Iron supplementation inhibits hypoxia-induced mitochondrial damage and protects zebrafish liver cells from death. Frontiers in Physiology. 13:925752

Yan, Q., Li, W., Gong, X., Hu, R., Chen, L. (2022) Transcriptomic and Phenotypic Analysis of CRISPR/Cas9-Mediated gluk2 Knockout in Zebrafish. Genes. 13(8)

Hu, R., Xu, Y., Han, B., Chen, Y., Li, W., Guan, G., Hu, P., Zhou, Y., Xu, Q., Chen, L. (2022) MiR-202-3p determines embryo viability during mid-blastula transition. Frontiers in cell and developmental biology. 10:897826

Wang, H., Wang, Y., Niu, M., Hu, L., Chen, L. (2022) Cold Acclimation for Enhancing the Cold Tolerance of Zebrafish Cells. Frontiers in Physiology. 12:813451

Han, X., Wang, B., Jin, D., Liu, K., Wang, H., Chen, L., Zu, Y. (2021) Precise Dose of Folic Acid Supplementation Is Essential for Embryonic Heart Development in Zebrafish. Biology. 11(1):

Wang, Y., Wang, H., Hu, L., Chen, L. (2021) Leptin Gene Protects Against Cold Stress in Antarctic Toothfish. Frontiers in Physiology. 12:740806

Putri, R.R., Chen, L. (2018) Spatiotemporal control of zebrafish (Danio rerio) gene expression using a light-activated CRISPR activation system. Gene. 677:273-279

Zhang, D., Hu, P., Liu, T., Wang, J., Jiang, S., Xu, Q., Chen, L. (2018) GC bias lead to increased small amino acids and random coils of proteins in cold-water fishes. BMC Genomics. 19:315

Chen, S., Yu, M., Chu, X., Li, W., Yin, X., Chen, L. (2017) Cold-induced retrotransposition of fish LINEs. Journal of genetics and genomics = Yi chuan xue bao. 44(8):385-394

Cao, L., Huang, Q., Wu, Z., Cao, D.D., Ma, Z., Xu, Q., Hu, P., Fu, Y., Shen, Y., Chan, J., Zhou, C.Z., Zhai, W., Chen, L. (2016) Neofunctionalization of zona pellucida proteins enhances freeze-prevention in the eggs of Antarctic notothenioids. Nature communications. 7:12987

NON-ZEBRAFISH PUBLICATIONS
1. Lixue Cao, Qiao Huang, Zhichao Wu, Dongdong Cao, Zhanling Ma, Qianghua Xu, Peng Hu, Yanxia Fu, Yu Shen, Jiulin Chan, Congzhao Zhou, Wanying Zhai, and Liangbiao Chen (2016) Neofunctionalization of zona pellucida proteins enhances freeze-prevention in the eggs of Antarctic notothenioids. Nature Comm. 7:12987.
2. Hu P, Liu M, Liu Y, Wang J, Zhang D, Niu H, Jiang S, Wang J, Zhang D, Han B, Xu Q, Chen L. (2016). Transcriptome comparison reveals a genetic network regulating the lower temperature limit in fish. Sci Rep. 6:28952. doi:10.1038/srep28952.
3. Xu Q, Zhang C, Zhang D, Jiang H, Peng S, Liu Y, Zhao K, Wang C, Chen L. (2016). Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments. BMC Evol Biol. 16:11.
4. Xu Q, Cai C, Hu X, Liu Y, Guo Y, Hu P, Chen Z, Peng S, Zhang D, Jiang S, Wu Z, Chan J, Chen L*.(2015) Evolutionary suppression of erythropoiesis via the modulation of TGF-β signaling in an Antarctic icefish. Mol. Ecol. ;24(18):4664-78.
5. Yang N.,Peng C., Cheng D., Huang Q., Xu G., Gao F., Chen L. * (2013). The over-expression of calmodulin from Antarctic notothenioid fish increases cold tolerance in tobacco. Gene.521(1):32-7
6. Qianghua Xu, Guang Li, Lixue Cao, Zhongjun Wang, Hua Ye, Xiaoyin Chen, Xi Yang, Yiquan Wang, Liangbiao Chen*. (2012). Proteomic characterization and evolutionary analyses of zona pellucida domain-containing proteins in the egg coat of the cephalochordate, Branchiostoma belcheri. BMC Evolutionary Biology. 12:239