ZFIN ID: ZDB-PERS-161014-2
Gopal, Suhasini R.
Email: sxg462@case.edu
URL: https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/41198945/
Affiliation: Alagramam Lab
Address: Suhasini R. Gopal, PhD. Research Scientist Department of Otolaryngology, Case Western Reserve University. 2058 Abington Road, Wearn bldg. 452, Cleveland, OH 44106.
Country: United States
Phone: 2165267454
Fax:
ORCID ID: 0000-0002-3525-3222


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Gopal, S.R., Lee, Y.T., Stepanyan, R., McDermott, B.M., Alagramam, K.N. (2019) Unconventional secretory pathway activation restores hair cell mechanotransduction in an USH3A model. Proceedings of the National Academy of Sciences of the United States of America. 116(22):11000-11009
Vargo, J.W., Walker, S.N., Gopal, S.R., Deshmukh, A.R., McDermott, B.M., Alagramam, K.N., Stepanyan, R. (2017) Inhibition of Mitochondrial Division Attenuates Cisplatin-Induced Toxicity in the Neuromast Hair Cells. Frontiers in Cellular Neuroscience. 11:393
Gopal, S.R., Chen, D.H., Chou, S.W., Zang, J., Neuhauss, S.C., Stepanyan, R., McDermott, B.M., Alagramam, K.N. (2015) Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35:10188-201

NON-ZEBRAFISH PUBLICATIONS
Kumar N. Alagramam and Suhasini R. Gopal. Methods of treating disorders associated with glycosylation defective proteins. US Patent No. WO 2018/068051 Al, Date: 12/04/2018.

Ruishuang Geng, Akil Omar, Suhasini Gopal, Daniel Chen, Astra Dinculescu, David Furness, David Saperstein, William Hauswirth, Lawrence R. Lustig; Kumar N. Alagramam. (2017) Modeling and preventing progressive hearing loss in Usher syndrome 3. Scientific Report. 7 (1): 13480.

Jonathon Vargo, Steven Walker, Suhasini R. Gopal, Aditi Deshmukh, Brian M. McDermott Jr, Kumar N. Alagramam and Ruben Stepanyan. (2017) Inhibition of Mitochondrial Division Attenuates Cisplatin-Induced Toxicity in the Neuromast Hair Cells. Frontiers in Cellular Neuroscience. 11: 393.

Alagramam KN, Suhasini R. Gopal, Geng R, Chen DH, Nemet I, Lee R, Tian G, Miyagi M, Malagu KF, Lock CJ, Esmieu WR, Owens AP, Lindsay NA, Ouwehand K, Albertus F, Fischer DF, Bürli RW, MacLeod AM, Harte WE, Palczewski K, Imanishi Y. (2016) A small molecule mitigates hearing loss in a mouse model of Usher syndrome III. Nat. Chem. Biol. 12(6):444-51. (Featured Article)

Suhasini R. Gopal, Daniel H.-C. Chen, Shih-Wei Chou, Jingjing Zang,, Stephan Neuhauss, Ruben Stepanyan, and Brian McDermott Jr and Kumar N. Alagramam. (2015) Zebrafish models for the mechanosensory hair cell dysfunction in Usher syndrome 3 reveal that clarin-1 is an essential hair bundle protein. J. Neurosci. 35(28): 10188-10201. (Featured Article)

Geng, R., Sotomayor, M., Kinder, K., Gopal, S.R., Gerka-Stuyt, J., Chen, D., Hardisty-Hughes, R., Ball, G., Parker, A., Gaudet, R., Furness, D., Brown, S.D.M., Corey, D.P., Alagramam, K.N. (2013) Noddy, a mouse harboring a missense mutation in protocadherin-15, reveals the impact of disrupting a critical interaction site between tip-link cadherins in inner ear hair cells. J. Neurosci. March 6; 33(10):4395-4404. (F1000 article recommendation: recommended as very good by Andy Groves, Baylor College of Medicine, Houston, TX, USA, on dated 22 April 2013.)

Suhasini G*, Sonaa E, Shila S, Srikumari CR, Jayaraman G and Ramesh A. (2011) Genetic admixture studies on four in situ evolved, two migrant and twenty one ethnic populations of Tamil Nadu, South India. Journal of Genetics, 90 (2): 191–202. (*Corresponding Author)

Kuppareddi Balamurugan, G. Suhasini, M. Vijaya, S. Kanthimathi, Nicole Mullins,Martin Tracey and George Duncan. (2010) Y chromosome STR allelic and haplotype diversity in five ethnic Tamil populations from Tamil Nadu, India. Legal Medicine, 12(5): 265–269.

Kuppareddi Balamurugan, Kanthimathi S, Vijaya M, Suhasini G, George Duncan, Martin Tracey and Bruce Budowle. (2010) Genetic variation of 15 autosomal short tandem repeat (STR) loci in four endogamous Tamil populations from Tamil Nadu, South India. Legal Medicine, 12(6): 320-323.