ZFIN ID: ZDB-PERS-160421-1
Asakawa, Kazuhide
Email: kasakawa@nig.ac.jp
URL: https://kazuhide-asakawa.com/
Affiliation:
Address: National Institute of Genetics 1111 Yata, Mishima, Shizuoka, 411-8540 Japan
Country: Japan
Phone: +81-55-981-6739
Fax: +81-55-981-5827
ORCID ID: 0000-0003-0628-1176


BIOGRAPHY AND RESEARCH INTERESTS
Development, homeostasis, ageing, and disease of the motor system


PUBLICATIONS
Asakawa, K., Handa, H., Kawakami, K. (2024) In Vivo Optogenetic Phase Transition of an Intrinsically Disordered Protein. Methods in molecular biology (Clifton, N.J.). 2707:257264257-264
Asakawa, K., Handa, H., Kawakami, K. (2023) Dysregulated TDP-43 proteostasis perturbs excitability of spinal motor neurons during brainstem-mediated fictive locomotion in zebrafish. Development, growth & differentiation. 65(8):446-452
Asakawa, K., Handa, H., Kawakami, K. (2023) [Optogenetic interrogation of TDP-43 cytotoxicity in a zebrafish ALS model]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 158:162016-20
Asakawa, K., Handa, H., Kawakami, K. (2022) Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae. Journal of visualized experiments : JoVE. (180):
Itoh, T., Takeuchi, M., Sakagami, M., Asakawa, K., Sumiyama, K., Kawakami, K., Shimizu, T., Hibi, M. (2020) Gsx2 is required for specification of neurons in the inferior olivary nuclei from Ptf1a-expressing neural progenitors in zebrafish. Development (Cambridge, England). 147(19):
Asakawa, K., Handa, H., Kawakami, K. (2020) Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons. Nature communications. 11:1004
Asatsuma-Okumura, T., Ando, H., De Simone, M., Yamamoto, J., Sato, T., Shimizu, N., Asakawa, K., Yamaguchi, Y., Ito, T., Guerrini, L., Handa, H. (2019) p63 is a cereblon substrate involved in thalidomide teratogenicity. Nature Chemical Biology. 15(11):1077-1084
Asakawa, K., Kawakami, K. (2018) Protocadherin-Mediated Cell Repulsion Controls the Central Topography and Efferent Projections of the Abducens Nucleus. Cell Reports. 24:1562-1572
Ohki, Y., Wenninger-Weinzierl, A., Hruscha, A., Asakawa, K., Kawakami, K., Haass, C., Edbauer, D., Schmid, B. (2017) Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration. Molecular neurodegeneration. 12:6
Kamezaki, A., Sato, F., Aoki, K., Asakawa, K., Kawakami, K., Matsuzaki, F., Sehara-Fujisawa, A. (2016) Visualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo. Scientific Reports. 6:28873
Kawakami, K., Asakawa, K., Hibi, M., Itoh, M., Muto, A., Wada, H. (2016) Gal4 Driver Transgenic Zebrafish: Powerful Tools to Study Developmental Biology, Organogenesis, and Neuroscience. Advances in genetics. 95:65-87
Kawakami, K., Asakawa, K., Muto, A., Wada, H. (2016) Tol2-mediated transgenesis, gene trapping, enhancer trapping, and Gal4-UAS system. Methods in cell biology. 135:19-37
Pujol-Martí, J., Zecca, A., Baudoin, J.P., Faucherre, A., Asakawa, K., Kawakami, K., and Lopez-Schier, H. (2012) Neuronal birth order identifies a dimorphic sensorineural map. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(9):2976-2987

NON-ZEBRAFISH PUBLICATIONS