ZFIN Person: Okuda, Kazuhide Shaun

ZFIN ID: ZDB-PERS-150713-1

Okuda, Kazuhide Shaun

Email:	kazuhideshaun.okuda@petermac.org
URL:	https://scholar.google.com/citations?user=HvKo1eMAAAAJ&hl=en
Affiliation:	Hogan Lab
Address:	Organogenesis and Cancer Program Peter MacCallum Cancer Centre 305 Grattan St Melbourne VIC 3000
Country:	Australia
Phone:	+61 7 3346 2222
Fax:	+61 7 3346 2101
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

Vascular Biology
Lymphatic
Disease Models
Cancer

PUBLICATIONS

Okuda, K.S., Ng, M.F., Ruslan, N.F., Bower, N.I., Song, D.S.S., Chen, H., Baek, S., Crosier, P.S., Koltowska, K., Astin, J.W., Tan, P.J., Hogan, B.M., Patel, V. (2021) 3,4-Difluorobenzocurcumin Inhibits Vegfc-Vegfr3-Erk Signalling to Block Developmental Lymphangiogenesis in Zebrafish. Pharmaceuticals (Basel, Switzerland). 14(7):

Okuda, K.S., Keyser, M.S., Gurevich, D.B., Sturtzel, C., Mason, E.A., Paterson, S., Chen, H., Scott, M., Condon, N.D., Martin, P., Distel, M., Hogan, B.M. (2021) Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis. eLIFE. 10:

Chaudhury, S., Okuda, K.S., Koltowska, K., Lagendijk, A.K., Paterson, S., Baillie, G.J., Simons, C., Smith, K.A., Hogan, B.M., Bower, N.I. (2020) Localised Collagen2a1 secretion supports lymphatic endothelial cell migration in the zebrafish embryo. Development (Cambridge, England). 147(18):

Okuda, K.S., Hogan, B.M. (2020) Endothelial Cell Dynamics in Vascular Development: Insights From Live-Imaging in Zebrafish. Frontiers in Physiology. 11:842

Vogrin, A.J., Bower, N.I., Gunzburg, M.J., Roufail, S., Okuda, K.S., Paterson, S., Headey, S.J., Stacker, S.A., Hogan, B.M., Achen, M.G. (2019) Evolutionary Differences in the Vegf/Vegfr Code Reveal Organotypic Roles for the Endothelial Cell Receptor Kdr in Developmental Lymphangiogenesis. Cell Reports. 28:2023-2036.e4

Grimm, L., Nakajima, H., Chaudhury, S., Bower, N.I., Okuda, K.S., Cox, A.G., Harvey, N.L., Koltowska, K., Mochizuki, N., Hogan, B.M. (2019) Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk. eLIFE. 8:

Baek, S., Oh, T.G., Secker, G., Sutton, D.L., Okuda, K.S., Paterson, S., Bower, N.I., Toubia, J., Koltowska, K., Capon, S.J., Baillie, G.J., Simons, C., Muscat, G.E.O., Lagendijk, A.K., Smith, K.A., Harvey, N.L., Hogan, B.M. (2019) The Alternative Splicing Regulator Nova2 Constrains Vascular Erk Signaling to Limit Specification of the Lymphatic Lineage. Developmental Cell. 49:279-292.e5

Eng, T.C., Chen, W., Okuda, K.S., Misa, J.P., Padberg, Y., Crosier, K.E., Crosier, P.S., Hall, C.J., Schulte-Merker, S., Hogan, B.M., Astin, J.W. (2019) Zebrafish facial lymphatics develop through sequential addition of venous and non-venous progenitors. EMBO reports. 20(5):

Tan, P. J., Lau, B. F., Krishnasamy, G., Ng, M. F., Husin, L. S., Ruslan, N., Song, D. S.S., Velaithan, V., Okuda, K. S., and Patel, V. (2018) Zebrafish embryonic development-interfering macrolides from Streptomyces californicus impact growth and mitochondrial function in human colorectal cancer cells. Process Biochemistry. 74:164-174

Samat, N., Ng, M.F., Ruslan, N.F., Okuda, K.S., Tan, P.J., Patel, V. (2018) Interference Potential of Tannins and Chlorophylls in Zebrafish Phenotypic-Based Assays. Assay and drug development technologies. 16(7):408-419

Okuda, K.S., Baek, S., Hogan, B.M. (2018) Visualization and Tools for Analysis of Zebrafish Lymphatic Development. Methods in molecular biology (Clifton, N.J.). 1846:55-70

Velaithan, V., Okuda, K.S., Ng, M.F., Samat, N., Leong, S.W., Faudzi, S.M., Abas, F., Shaari, K., Cheong, S.C., Tan, P.J., Patel, V. (2017) Erratum to: Zebrafish phenotypic screen identifies novel Notch antagonists. Investigational new drugs.

Velaithan, V., Okuda, K.S., Ng, M.F., Samat, N., Leong, S.W., Faudzi, S.M., Abas, F., Shaari, K., Cheong, S.C., Tan, P.J., Patel, V. (2017) Zebrafish phenotypic screen identifies novel notch antagonists. Investigational new drugs. 35(2):166-179

Dalton, J.P., Uy, B., Okuda, K.S., Hall, C.J., Denny, W.A., Crosier, P.S., Swift, S., Wiles, S. (2017) Screening of anti-mycobacterial compounds in a naturally infected zebrafish larvae model. The Journal of antimicrobial chemotherapy. 72(2):421-427

Okuda, K.S., Lee, H.M., Velaithan, V., Ng, M.F., Patel, V. (2016) Utilizing zebrafish to identify anti-(lymph)angiogenic compounds for cancer treatment: promise and future challenges. Microcirculation (New York, N.Y. : 1994). 23(6):389-405

Okuda, K.S., Tan, P.J., Patel, V. (2016) Sprouting Buds of Zebrafish Research in Malaysia: First Malaysia Zebrafish Disease Model Workshop. Zebrafish. 13(2):138-41

Okuda, K.S., Misa, J.P., Oehlers, S.H., Hall, C.J., Ellett, F., Alasmari, S., Lieschke, G.J., Crosier, K.E., Crosier, P.S., Astin, J.W. (2015) A zebrafish model of inflammatory lymphangiogenesis. Biology Open. 4(10):1270-80

Oehlers, S.H., Cronan, M.R., Scott, N.R., Thomas, M.I., Okuda, K.S., Walton, E.M., Beerman, R.W., Crosier, P.S., Tobin, D.M. (2015) Interception of host angiogenic signalling limits mycobacterial growth. Nature. 517(7536):612-5

Astin, J.W., Haggerty, M.J., Okuda, K.S., Le Guen, L., Misa, J.P., Tromp, A., Hogan, B.M., Crosier, K.E., Crosier, P.S. (2014) Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sprouting. Development (Cambridge, England). 141(13):2680-90

Oehlers, S.H., Flores, M.V., Hall, C.J., Okuda, K.S., Sison, J.O., Crosier, K.E., and Crosier, P.S. (2013) Chemically Induced Intestinal Damage Models in Zebrafish Larvae. Zebrafish. 10(2):184-93

Okuda, K.S., Astin, J.W., Misa, J.P., Flores, M.V., Crosier, K.E., and Crosier, P.S. (2012) lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish. Development (Cambridge, England). 139(13):2381-2391

Oehlers, S.H., Flores, M.V., Okuda, K.S., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2011) A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents. Developmental dynamics : an official publication of the American Association of Anatomists. 240(1):288-298

NON-ZEBRAFISH PUBLICATIONS