ZFIN ID: ZDB-PERS-140417-1 |
Wang, Qiang
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BIOGRAPHY AND RESEARCH INTERESTS
Dr. Qiang Wang
Born: November 1, 1975 in China.
professor in the Institute of Zoology, Chinese Academy of Sciences, Beijing, P. R. China (100101),
Tel: 86-10-64807895 (lab)
Fax: 86-10-64807895
E-mail: qiangwang@ioz.ac.cn
Dr. Wang is professor at State Key Laboratory of Biomembrane and Membrane Biotechnology in the Institute of Zoology, Chinese Academy of Sciences, and he is a recipient of National Science Fund for Excellent Young Scholars. Dr. Wang mainly works on signal transduction regulation, and has made significant progress in elucidating the regulation mechanism of TGF-β superfamily signaling during early embryo development and tissue formation. The related papers were published on the famous international academic journals such as Developmental Cell, Blood, Molecular and Cellular Biology, J Biol.Chem. etc.
EDUCATION
Postdoctoral fellowship in Molecular Cell Biology Lab, Departement of Biological Sciences and Biotechnology, Tsinghua Unversity, Beijing, P. R. China, July, 2004~2008.
Ph.D. in Lab of Developmental Immunology, College of Life Science, Shandong University, Shandong province, P. R. China, 1999~2004 (Major thesis research done in Pathology Department, Peking Univeristy Health Science Centre, November, 2001~ March, 2004).
B.S. in Biological Science, College of Life Science, Shandong University, Shandong province, Beijing, P. R. China, 1999.
WORK EXPERIENCE
Associate professor in the Institute of Zoology, Chinese Academy of Sciences, 2008~2012, Beijing, P. R. China
Professor in the Institute of Zoology, Chinese Academy of Sciences, 2013~present, Beijing, P. R. China
MAIN RESEARCH FIELDS:
We are particularly interested in the roles of TGF-β/Nodal and Wnt signaling pathways in mesoderm induction and dorsovental patterning of vertebrate embryos. Genes mediating Nodal and Wnt signaling in zebrafish embryos are being studied using genetic, biochemical and molecular approaches. We also aim to understand the functional importance of microRNAs in early development of zebrafish embryos.
Born: November 1, 1975 in China.
professor in the Institute of Zoology, Chinese Academy of Sciences, Beijing, P. R. China (100101),
Tel: 86-10-64807895 (lab)
Fax: 86-10-64807895
E-mail: qiangwang@ioz.ac.cn
Dr. Wang is professor at State Key Laboratory of Biomembrane and Membrane Biotechnology in the Institute of Zoology, Chinese Academy of Sciences, and he is a recipient of National Science Fund for Excellent Young Scholars. Dr. Wang mainly works on signal transduction regulation, and has made significant progress in elucidating the regulation mechanism of TGF-β superfamily signaling during early embryo development and tissue formation. The related papers were published on the famous international academic journals such as Developmental Cell, Blood, Molecular and Cellular Biology, J Biol.Chem. etc.
EDUCATION
Postdoctoral fellowship in Molecular Cell Biology Lab, Departement of Biological Sciences and Biotechnology, Tsinghua Unversity, Beijing, P. R. China, July, 2004~2008.
Ph.D. in Lab of Developmental Immunology, College of Life Science, Shandong University, Shandong province, P. R. China, 1999~2004 (Major thesis research done in Pathology Department, Peking Univeristy Health Science Centre, November, 2001~ March, 2004).
B.S. in Biological Science, College of Life Science, Shandong University, Shandong province, Beijing, P. R. China, 1999.
WORK EXPERIENCE
Associate professor in the Institute of Zoology, Chinese Academy of Sciences, 2008~2012, Beijing, P. R. China
Professor in the Institute of Zoology, Chinese Academy of Sciences, 2013~present, Beijing, P. R. China
MAIN RESEARCH FIELDS:
We are particularly interested in the roles of TGF-β/Nodal and Wnt signaling pathways in mesoderm induction and dorsovental patterning of vertebrate embryos. Genes mediating Nodal and Wnt signaling in zebrafish embryos are being studied using genetic, biochemical and molecular approaches. We also aim to understand the functional importance of microRNAs in early development of zebrafish embryos.
PUBLICATIONS
NON-ZEBRAFISH PUBLICATIONS
[1] Y. Li, X. Kang, and Q. Wang*, HSP70 decreases receptor-dependent phosphorylation of Smad2 and blocks TGF-beta-induced epithelial-mesenchymal transition. J Genet Genomics 38 (2011) 111-116. (Corresponding author)
[2] W. Zhang, Y. Jiang, Q. Wang, X. Ma, Z. Xiao, W. Zuo, X. Fang, and Y.G. Chen, Single-molecule imaging reveals transforming growth factor-beta-induced type II receptor dimerization. Proc Natl Acad Sci U S A 106 (2009) 15679-15683.
[3] Q. Wang, Z. Huang, H. Xue, C. Jin, X.L. Ju, J.D. Han, and Y.G. Chen, MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4. Blood 111 (2008) 588-595.
[4] J. Yu, Q. Wang, X. Shi, X. Ma, H. Yang, Y.G. Chen, and X. Fang, Single-molecule force spectroscopy study of interaction between transforming growth factor beta1 and its receptor in living cells. J Phys Chem B 111 (2007) 13619-13625.
[5] X. Ma, Q. Wang, Y. Jiang, Z. Xiao, X. Fang, and Y.G. Chen, Lateral diffusion of TGF-beta type I receptor studied by single-molecule imaging. Biochem Biophys Res Commun 356 (2007) 67-71.
[6] J. Ma*, Q. Wang*, T. Fei, J.D. Han, and Y.G. Chen, MCP-1 mediates TGF-beta-induced angiogenesis by stimulating vascular smooth muscle cell migration. Blood 109 (2007) 987-94. (*Co-first author)
[7] Y.G. Chen, Q. Wang, S.L. Lin, C.D. Chang, J. Chuang, and S.Y. Ying, Activin signaling and its role in regulation of cell proliferation, apoptosis, and carcinogenesis. Exp Biol Med (Maywood) 231 (2006) 534-44.
[8] Q. Wang, Z. Bai, X. Li, L. Hou, and B. Zhang, The evidences of human orphan receptor COUP-TFII inhibiting telomerase activity through decreasing hTERT transcription. Cancer Lett 214 (2004) 81-90.
[9] J. Lv, H. Liu, Q. Wang, Z. Tang, L. Hou, and B. Zhang, Molecular cloning of a novel human gene encoding histone acetyltransferase-like protein involved in transcriptional activation of hTERT. Biochem Biophys Res Commun 311 (2003) 506-13.