ZFIN Person: Kelley, Clair

Biography and Research Interest

Research Lab Specialist, Laboratory of Dr. Wilson Clements, St. Jude Children's Research Hospital
Research Lab Specialist, Laboratory of Dr. Paul Mead, St. Jude Children's Research Hospital
Assistant Member, Department of Pathology, St. Jude Children's Research Hospital
Postdoctoral Research Fellow, Massachusetts General Hospital, Harvard Medical School
Laboratory of Dr. Katia Georgopoulos
Ph.D. Harvard University, Division of Medical Sciences
Cell and Developmental Biology, Laboratory of Dr. Leonard Zon
B.S. Biochemistry, California Polytechnic State University, San Luis Obispo

Publications

Non-Zebrafish Publications

Yergeau DA, Kelley CM, Zhu H, Kuliyev E, Mead PE. Forward genetic screens in Xenopus using transposon-mediated insertional mutagenesis. Methods in Molecular Biology 2012 vol. 917 (in press).

Kelley CM, Yergeau DA, Zhu H, Kuliyev E, Mead PE. Xenopus Transgenics: Methods using transposons. Methods in Molecular Biology 2012 vol. 917 (in press).

Yergeau DA, Kelley CM, Kuliyev E, Zhu H, Johnson Hamlet MR, Sater AK, Wells DE, Mead PE. (2011) Remobilization of Sleeping Beauty transposons in the germline of Xenopus tropicalis. Mob DNA. Nov 24;2:15.

Yergeau DA, Kelley CM, Zhu H, Kuliyev E, Mead PE. (2010) Transposon transgenesis in Xenopus. Methods. May;51(1):92-100.

Yergeau DA, Kelley CM, Kuliyev E, Zhu H, Sater AK, Wells DE, Mead PE. (2010) Remobilization of Tol2 transposons in Xenopus tropicalis. BMC Dev Biol. Jan 22;10:11.

Yergeau DA, Johnson Hamlet MR, Kuliyev E, Zhu H, Doherty JR, Archer TD, Subhawong AP, Valentine MB, Kelley CM, Mead PE. (2009) Transgenesis in Xenopus using the Sleeping Beauty transposon system. Dev Dyn. 2009 Jul;238(7):1727-43.

Kelley, C. M. , Koipally, J., Cortes, M. and Georgopoulos, K. (2001) The role of Ikaros family proteins in lymphoid development and homeostasis. In "Hematopoiesis: A Developmental Approach" Oxford University Press. Dr. Leonard Zon, editor. pp 487-495.

Koipally J, Kim J, Jones B, Jackson A, Avitahl N, Winandy S, Trevisan M, Nichogiannopoulou A, Kelley C, Georgopoulos K. (1999) Ikaros chromatin remodeling complexes in the control of differentiation of the hemo-lymphoid system. In Cold Spring Harb Symp Quant Biol. 64:79-86.

Kelley C. M. , Ikeda T., Koipally J., Avitahl N., Wu L., Georgopoulos K. and Morgan B.A. (1998). Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Current Biology 8,508-515.

Mead, P. E., Kelley, C. M., Hahn, P., Piedad, O. and Zon, L. I. (1998) SCL specifies hematopoietic mesoderm in Xenopus embryos. Development 125, 2611-2620.

Kelley, C. M.*, Turpen, J.*, Mead, P. E. and Zon, L. I. (1997) Bipotential primitive-definitive hematopoietic progenitors in the vertebrate embryo. Immunity 7,325-34. (*denotes equal contribution of first two authors).

Maeno, M., Mead, P. E., Kelley, C., Xu, R., Kung, H., Suzuki, A., Ueno, N. and Zon, L. I. (1996) The role of BMP-4 and GATA-2 in the induction and differentiation of ventral mesoderm. Blood 88, 1975-1972.

Mead, P. E, Brivanlou, I. H., Kelley, C. M. and Zon, L. I. (1996) The homeobox gene Mix.1 is a BMP-4 responsive regulator of dorsal-ventral patterning. Nature 382, 357-360.

Winardi, R., Discher, D., Kelley, C., Zon, L., Mays, K., Mohandas, N. and Conboy, JG. (1995) Evolutionarily conserved alternative pre-mRNA splicing regulates structure and function of the spectrin-actin binding domain of erythroid protein 4.1. Blood 86, 4315-22.

Kelley, C., Yee, K., Harland, R. M. and Zon, L. I. (1994). Ventral expression of GATA-1 and GATA-2 in the Xenopus embryo defines induction of hematopoietic mesoderm. Developmental Biology 165, 193-205.

Kelley, C., Blumberg, H., Zon, L.I. and Evans, T. (1993). GATA-4 is a novel transcription factor expressed in endocardium of the developing heart. Development. 118, 817-827.

Yashar, M. B., Kelley C., Yee, K., Errede, B. and Zon, L. I. (1993) Novel members of the mitogen-activated protein kinase activator family in Xenopus laevis. Mol. Cell Bio. 13, 5738-5748.

Adler, H. T., Reynolds, P. J., Kelley, C. M. and Sefton, B. M. (1988). Transcriptional activation of lck by retrovirus promoter insertion between two lymphoid specific promoters. J Virol. 62, 4113-4122.