Person
Anbalagan, Savani
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Biography and Research Interest
Savani Anbalagan received his Masters from SASTRA University in India. He did his PhD research in Prof. Maria Pia Longhese's group at Univ. of Milano-Bicocca (Italy) on mechanisms protecting telomeres using budding yeast. He was awarded his PhD degree in 2014. After his PhD, he moved to Israel for a post-doctoral fellowship (2013-2019) in Prof. Gil Levkowitz's group at the Weizmann Institute of Science (Israel). Using zebrafish as vertebrate model organism, he studied how glial pituicytes promote neurohypophyseal oxytocin content and the neurohypophyseal endothelial decision to form blood-brain barrier (BBB)-less permeable capillaries (Dev Cell 2018; Elife 2019). Currently, he is a principal investigator at the Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University (AMU) in Poznań, Poland. At AMU, he established the first zebrafish facility and continue to explore the role of glial pituicytes on neurohypophyseal neurovascular morphogenesis. He led the development of the zebrafish ligand-receptor atlas, a valuable resource for the zebrafish research community (iScience 2023) and he also proposed gasocrine signaling and oxygen gasoreceptors (Am J Physiol Endocrinol Metab. 2024).
OTHER ROLES
Member of thesis advisory committee of Ms. Ruchi Jain, doctoral student in Prof. Vladimir Korzh research group at IIMCB, Poland.
OTHER ROLES
Member of thesis advisory committee of Ms. Ruchi Jain, doctoral student in Prof. Vladimir Korzh research group at IIMCB, Poland.
Non-Zebrafish Publications
Anbalagan, S. (2021) Endocrine cross-talk between the gut microbiome and glial cells in development and disease. J Neuroendocrinol. 2021 May;33(5):e12924. doi: 10.1111/jne.12924.
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Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends.
Bonetti D, Anbalagan S, Lucchini G, Clerici M, Longhese MP.
EMBO J. 2013 Jan 23;32(2):275-89. doi: 10.1038/emboj.2012.327. Epub 2012 Dec
The role of shelterin in maintaining telomere integrity.
Longhese MP, Anbalagan S, Martina M, Bonetti D.
Front Biosci (Landmark Ed). 2012 Jan 1;17:1715-28. Review.
Rif1 supports the function of the CST complex in yeast telomere capping.
Anbalagan S, Bonetti D, Lucchini G, Longhese MP.
PLoS Genet. 2011 Mar;7(3):e1002024. doi: 10.1371/journal.pgen.1002024. Epub 2011 Mar 17.
Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeres.
Bonetti D, Clerici M, Anbalagan S, Martina M, Lucchini G, Longhese MP.
PLoS Genet. 2010 May 27;6(5):e1000966. doi: 10.1371/journal.pgen.1000966.