Biography and Research Interest

My personal motivation is in improving people?s lives by utilizing proven but unused technology.

Publications

Non-Zebrafish Publications

1. Ahmed, N., Zeng, M., Sinha, I., Polin, L., Wei W-Z., Rathinam, C., Flavell, R., Massoumi, R. & Venuprasad, K. (2011) The E3 ligase Itch and deubiquitinase Cyld act together to regulate inflammation. Nat. Immunol. (Advanced Online Publication)

2. *Benchaala, I., *Sinha, I., *Wykes, S., Hali, M., Mishra, M. Kotta, K., Kannan, R.M. & J. Whittum-Hudson. (2009) Targeted delivery of nanodevices to Chlamydia trachomatis infected tissues in murine reactive arthritis. Arthrit. Rheum. 60: 10. (*equal contributors)

3. Mishra, M.K., Kotta, K., Benchaala, I., Wykes, S., Hali, M., Sinha, I., Whittum-Hudson, J. & Kannan, R.M. (2009) Development of PAMAM-dendrimer based nanodevices for targeted delivery to Chlamydia trachomatis infection. Polym. Mat. Sci. Eng. 100: 09.

4. Zhang, T., Nirantar, S., Lim, H.H., Sinha, I. & Surana, U. (2009) DNA damage checkpoint maintains Cdh1 in an active state to inhibit anaphase progression. Dev. Cell 17: 541-551.

5. Sinha, I., Wang, Y.M., Philp, R., Li, C.R., Yap, W.H. & Wang, Y. (2007) Cyclindependent kinases control septin phosphorylation in Candida albicans hyphal development. Dev. Cell 13: 421-432.

6. Sinha, I. & Dick, T. (2004) Role of malonyl coenzyme A: Acyl carrier protein transacylase (MCAT) in the growth-inhibitory effect of the calmodulin antagonist trifluoperazine in Mycobacterium bovis BCG. J. Antimicrob. Chemother. 53: 1072-1075.

7. Sinha, I., Boon, C. & Dick, T. (2003) Apparent growth phase-dependent phosphorylation of malonyl coenzyme A: Acyl carrier protein transacylase (MCAT), a major fatty acid synthase II component in Mycobacterium bovis BCG. FEMS Microbiol. Lett. 227: 141-147.

8. Virdi, J.S., Sinha, I., Rajendran P. & Singh I. (2001) Arsenite-induced multiple antibiotic resistance phenotypes in environmental isolates of Yersinia enterocolitica. Current Microbiology 43: 144-146.

9. Sinha, I. & Virdi, J. S. (2000) Differentiation of non-pathogenic (biotype 1A) Yersinia enterocolitica from pathogenic bioserotypes by sodium acetate utilization. Journal of Medical Microbiology 49: 674-676.

10. Bansal, N., Sinha, I. & Virdi, J.S. (2000) Virulence plasmid (pYV)-associated susceptibility of Yersinia enterocolitica to chlorine and heavy metals. Journal of Applied Microbiology 89: 663-667.

11. Bansal, N., Sinha, I. & Virdi, J.S. (2000) Arsenic and cadmium resistance in environmental isolates of Yersinia enterocolitica and Yersinia intermedia. Canadian Journal of Microbiology 46: 481-484.

12. Sinha, I. & Virdi, J.S. (2000) In vitro antibiotic susceptibilities of Yersinia enterocolitica and Yersinia intermedia isolated from sewage effluents. Current Science 79: 90-92.

13. Sinha, I. & Virdi, J.S. (2000) Isolation of Yersinia enterocolitica and Yersinia intermedia from wastewaters and their biochemical and serological characteristics. Current Science 2000, 79: 510-513.

14. Benchaala, I., Sinha, I., Hali, M., Gerard, H., Bharatwaj, B, Hudson., A., Rocha, S. and Whittum-Hudson, J. (2011). Reduction in Chlamydia trachomatis-associated murine reactive arthritis by novel peptide vaccine candidates. Oral presentation at ACR/ARHP Scientific meeting 11, Chicago, USA, Nov 5-9.

15. Whittum-Hudson, J., Hali, M., Sinha, I., Bharatwaj, B., Oszust, C., Hudson, A. and da Rocha, S. (2011) Novel Mimotope Peptides as anti-chlamydial vaccine candidates. Poster presentation at 15th International Congress of Mucosal Immunology, Paris, France, July 5-9.

16. Peng, D.J., Sinha, I., Zeng, M., Subramaniam, M., Spelsberg, T.C. and Venuprasad, K. (2010) Non-canonical K-27 linked polyubiquitination of TIEG1 regulates Foxp3 expression and tumor growth. Poster presentation at 39th Autumn Immunology Conference, Chicago, IL, USA, Nov. 19-22.

17. Bonneau, P., Macpharlin, C., Hali, M., Benchaala, I., Sinha, I., Kannan, R., Mishra, M. and Whittum-Hudson, J. (2010). Characterizing Therapeutic Effects of Antibioticloaded Nanodevices in Chlamydial Infections. Medical student summer research symposium, Chemical Engineering & Materials Science, College of Engineering, Wayne State University, Detroit, USA.

18. Mishra, M.K., Kotta, K., Benchaala, I., Wykes, S.M., Hali, M., Sinha, I., Whittum-Hudson, J. and Kannan, R.M. (2009) Development of Folate-PAMAM and Azithromycin-PAMAM Nanodevices for Biodistribution, Imaging, Cellular Uptake, and Targeted Delivery to Chlamydial Infections. Poster presentation at AIChE Annual Meeting, Nashville, TN, USA, Nov. 8-13.

19. Benchaala, I., Sinha, I., Wykes, S.M., Hali, M., Mishra, M., Kotta, K., Kannan, R.M., Whittum-Hudson, J.A. (2009) Targeted delivery of Nanoparticles to Chlamydia trachomatis?infected tissues in murine reactive arthritis. Oral presentation at ACR/ARHP Scientific meeting 09, Philadelphia, Pennsylvania, USA, Oct 17-21.

20. Mishra, M.K., Kotta, K., Benchaala, I., Wykes, S., Hali, M., Sinha, I., Whittum-Hudson, J. and Kannan, R.M. (2009) Development of PAMAM-dendrimer based nanodevices for targeted delivery to Chlamydia trachomatis infection. Poster presentation at Nanoscience: Challenges for the Future: 237th ACS National Meeting & Exposition, Salt Lake City, UT, Mar. 22-26.

21. Sinha, I., Oszust, C., Sekhon, K., Wu, L. Hali, M., da Rocha, S., Hudson, A., Whittum-Hudson, J. (2009) Test of novel peptides as anti-chlamydial vaccine candidates. Oral presentation at CBRS 2009: 4th Biennial Meeting of the Chlamydia Basic Research Society, Little Rock, Arkansas, USA, Mar. 20-23.

22. Whittum-Hudson, J., Benchaala, I., Wykes, S., Hali, M., Sinha, I., Mishra, M., Kotta, K., Kannan, R.M. (2009) Development of PAMAM-dendrimer based nanodevices for targeted delivery to Chlamydia trachomatis infection. Poster presentation at CBRS 2009: 4th Biennial Meeting of the Chlamydia Basic Research Society, Little Rock, Arkansas, USA, Mar. 20-23.

23. Sekhon, K., Wykes, S., Sovinski, A., Toti, U., Hali, M., Sinha, I., Gérard, H., Hudson, A., Panyam, J., Whittum-Hudson, J. (2009) Use of nanotechnology to target acutely and persistently Chlamydia-infected cells for therapy and imaging in vitro and in vivo. Poster presented at CBRS 2009: 4th Biennial Meeting of the Chlamydia Basic
Research Society, Little Rock, Arkansas, USA, Mar. 20-23.

24. Sinha, I., Wang, Y.M., Philp, R., Li, C.R., Yap, W.H. and Wang, Y. (2008) Septin phosphorylation in Candida albicans during hyphal development. ASM Conferences: 9th Candida and Candidiasis, Jersey City, NJ, USA, Mar. 24-28.

25. Sinha, I. and Dick, T. (2004) Role of malonyl coenzyme A: Acyl carrier protein transacylase (MCAT) in the growth-inhibitory effect of the calmodulin antagonist trifluoperazine in Mycobacterium bovis BCG. Oral presentation at NITD Inaugural Symposium on Dengue Fever and Tuberculosis, Singapore, Jul. 5-6.

26. Sinha, I., Boon, C. and Dick, T. (2003) Growth phase-dependent Proteome phosphorylation in Mycobacterium bovis BCG. Poster presentation at the 103rd ASM conference, Washington DC, USA, May. 2003.

27. Sinha, I., Boon, C. and Dick, T. (2003) Growth phase-dependent Proteome phosphorylation in Mycobacterium bovis BCG. Oral presentation at NITD Inaugural Symposium on Dengue Fever and Tuberculosis, Singapore, Jan. 22-23.

28. Sinha, I., Boon C., and Dick, T. (2002) Growth phase-independent proteome phosphorylation in Mycobacterium bovis BCG. Oral presentation at the Second International Conference on Structural Biology and Functional Genomics, Singapore, Dec. 2-4.

29. Sinha, I. and Virdi, J. S. (2000) Environmental Yersinia enterocolitica biotype 1A produce water-soluble siderophore(s) but lack yersiniophore. Oral presentation at 40th Annual Conference of AMI at Bhubaneswar, India. Jan. 22-24.