ZFIN Person: Wheeler, Robert

ZFIN ID: ZDB-PERS-110831-1

Wheeler, Robert

Email:	robert.wheeler1@maine.edu
URL:
Affiliation:	Wheeler Lab
Address:	Molecular and Biomedical Sciences University of Maine 5735 Hitchner Hall Orono, ME 04469
Country:
Phone:	207-581-2890
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Hattab, S., Dagher, A.M., Wheeler, R.T. (2022) Pseudomonas Synergizes with Fluconazole against Candida during Treatment of Polymicrobial Infection. Infection and Immunity. 90(4):e0062621

Scherer, A.K., Blair, B.A., Park, J., Seman, B.G., Kelley, J.B., Wheeler, R.T. (2020) Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast. PLoS pathogens. 16:e1008414

Ho, J., Yang, X., Nikou, S.A., Kichik, N., Donkin, A., Ponde, N.O., Richardson, J.P., Gratacap, R.L., Archambault, L.S., Zwirner, C.P., Murciano, C., Henley-Smith, R., Thavaraj, S., Tynan, C.J., Gaffen, S.L., Hube, B., Wheeler, R.T., Moyes, D.L., Naglik, J.R. (2019) Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor. Nature communications. 10:2297

Archambault, L.S., Trzilova, D., Gonia, S., Gale, C., Wheeler, R.T. (2019) Intravital Imaging Reveals Divergent Cytokine and Cellular Immune Responses to Candida albicans and Candida parapsilosis. mBio. 10(3):

Petit, J., Bailey, E.C., Wheeler, R.T., de Oliveira, C.A.F., Forlenza, M., Wiegertjes, G.F. (2019) Studies Into β-Glucan Recognition in Fish Suggests a Key Role for the C-Type Lectin Pathway. Frontiers in immunology. 10:280

Rosowski, E.E., Knox, B.P., Archambault, L.S., Huttenlocher, A., Keller, N.P., Wheeler, R.T., Davis, J.M. (2018) The Zebrafish as a Model Host for Invasive Fungal Infections. Journal of fungi (Basel, Switzerland). 4(4)

Seman, B.G., Moore, J.L., Scherer, A.K., Blair, B.A., Manandhar, S., Jones, J.M., Wheeler, R.T. (2018) Yeast and filaments have specialized, independent activities in a zebrafish model of Candida albicans infection.. Infection and Immunity. 86(10):

Bergeron, A.C., Seman, B.G., Hammond, J.H., Archambault, L.S., Hogan, D.A., Wheeler, R.T. (2017) Candida and Pseudomonas interact to enhance virulence of mucosal infection in transparent zebrafish.. Infection and Immunity. 85(11)

Gratacap, R.L., Scherer, A.K., Seman, B.G., Wheeler, R.T. (2017) Control of mucosal candidiasis in the zebrafish swimbladder depends on neutrophils that block filament invasion and drive extracellular trap production. Infection and Immunity. 85(9)

Gonia, S., Archambault, L., Shevik, M., Altendahl, M., Fellows, E., Bliss, J.M., Wheeler, R.T., Gale, C.A. (2017) Candida parapsilosis Protects Premature Intestinal Epithelial Cells from Invasion and Damage by Candida albicans.. Frontiers in pediatrics. 5:54

Bergeron, A.C., Barker, S.E., Brothers, K.M., Prasad, B.C., Wheeler, R.T. (2017) Polyclonal anti-Candida antibody improves phagocytosis and overall outcome in zebrafish model of disseminated candidiasis. Developmental and comparative immunology. 68:69-78

Mallick, E.M., Bergeron, A.C., Jones, S.K., Newman, Z.R., Brothers, K.M., Creton, R., Wheeler, R.T., Bennett, R.J. (2016) Phenotypic Plasticity Regulates Candida albicans Interactions and Virulence in the Vertebrate Host. Frontiers in microbiology. 7:780

Leach, M.D., Farrer, R.A., Tan, K., Miao, Z., Walker, L.A., Cuomo, C.A., Wheeler, R.T., Brown, A.J., Wong, K.H., Cowen, L.E. (2016) Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans. Nature communications. 7:11704

Voelz, K., Gratacap, R.L., Wheeler, R.T. (2015) A zebrafish larval model reveals early tissue-specific innate immune responses to Mucor circinelloides. Disease models & mechanisms. 8(11):1375-88

Gratacap, R.L., Bergeron, A.C., Wheeler, R.T. (2014) Modeling Mucosal Candidiasis in Larval Zebrafish by Swimbladder Injection. Journal of visualized experiments : JoVE. (93):e52182

Gratacap, R.L., and Wheeler, R.T. (2014) Utilization of zebrafish for intravital study of eukaryotic pathogen-host interactions. Developmental and comparative immunology. 46(1):108-115

Gratacap, R.L., Rawls, J.F., and Wheeler, R.T. (2013) Mucosal candidiasis elicits NF-κB activation, proinflammatory gene expression and localized neutrophilia in zebrafish. Disease models & mechanisms. 6(5):1260-70

Brothers, K.M., Gratacap, R.L., Barker, S.E., Newman, Z.R., Norum, A., and Wheeler, R.T. (2013) NADPH Oxidase-Driven Phagocyte Recruitment Controls Candida albicans Filamentous Growth and Prevents Mortality. PLoS pathogens. 9(10):e1003634

Brothers, K.M., and Wheeler, R.T. (2012) Non-invasive Imaging of Disseminated Candidiasis in Zebrafish Larvae. Journal of visualized experiments : JoVE. (65)

Tobin, D.M., May, R.C., and Wheeler, R.T. (2012) Zebrafish: a see-through host and a fluorescent toolbox to probe host-pathogen interaction. PLoS pathogens. 8(1):e1002349

Brothers, K., Newman, Z., and Wheeler, R. (2011) Live imaging of disseminated candidiasis in zebrafish reveals role of phagocyte oxidase in limiting filamentous growth. Eukaryotic Cell. 10(7):932-44

NON-ZEBRAFISH PUBLICATIONS