ZFIN ID: ZDB-PERS-110223-3
Shin, Chong
Email: chong.shin@biology.gatech.edu
URL: http://www.biology.gatech.edu/people/index.php?id=chong-shin
Affiliation: Chong Shin lab
Address: School of Biology and Parker H. Petit Institute for Bioengineering and Bioscience Georgia Institute of Technology 315 Ferst Dr. NW Atlanta, GA 30332 USA
Country: United States
Phone: 404-385-4211
Fax: 404-894-0519

I am interested in delineating the molecular and genetic pathways that program or reprogram cells into a specific lineage, with a primary focus on hepatopancreatic lineages.

Xu, J., Jia, Y.F., Tapadar, S., Weaver, J.D., Raji, I.O., Pithadia, D.J., Javeed, N., García, A.J., Choi, D.S., Matveyenko, A.V., Oyelere, A.K., Shin, C.H. (2018) Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells. Scientific Reports. 8:15587
Mojib, N., Xu, J., Bartolek, Z., Imhoff, B., McCarty, N.A., Shin, C.H., Kubanek, J. (2017) Zebrafish aversive taste co-receptor is expressed in both chemo- and mechanosensory cells and plays a role in lateral line development. Scientific Reports. 7:13475
Bourassa, D., Gleber, S.C., Vogt, S., Shin, C.H., Fahrni, C.J. (2016) MicroXRF tomographic visualization of zinc and iron in the zebrafish embryo at the onset of the hatching period. Metallomics : integrated biometal science. 8(10):1122-1130
Huang, M., Xu, J., Shin, C.H. (2016) Development of an Ethanol-induced Fibrotic Liver Model in Zebrafish to Study Progenitor Cell-mediated Hepatocyte Regeneration. Journal of visualized experiments : JoVE. (111):e54002
Xu, J., Cui, J., Del Campo, A., Shin, C.H. (2016) Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration. PLoS Genetics. 12:e1005831
Huang, M., Chang, A., Choi, M., Zhou, D., Anania, F.A., Shin, C.H. (2014) Antagonistic interaction between Wnt and Notch activity modulates the regenerative capacity of a zebrafish fibrotic liver model. Hepatology (Baltimore, Md.). 60(5):1753-66
Bourassa, D., Gleber, S.C., Vogt, S., Yi, H., Will, F., Richter, H., Shin, C.H., Fahrni, C.J. (2014) 3D imaging of transition metals in the zebrafish embryo by X-ray fluorescence microtomography. Metallomics : integrated biometal science. 6(9):1648-55
Boglev, Y., Badrock, A.P., Trotter, A.J., Du, Q., Richardson, E.J., Parslow, A.C., Markmiller, S.J., Hall, N.E., de Jong-Curtain, T.A., Ng, A.Y., Verkade, H., Ober, E.A., Field, H.A., Shin, D., Shin, C.H., Hannan, K.M., Hannan, R.D., Pearson, R.B., Kim, S.H., Ess, K.C., Lieschke, G.J., Stainier, D.Y., and Heath, J.K. (2013) Autophagy induction is a tor- and tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis. PLoS Genetics. 9(2):e1002379
Anderson, R.M., Bosch, J.A., Goll, M.G., Hesselson, D., Dong, P.D., Shin, D., Chi, N.C., Shin, C.H., Schlegel, A., Halpern, M., and Stainier, D.Y. (2009) Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration. Developmental Biology. 334(1):213-223
Chung, W.S., Shin, C.H., and Stainier, D.Y. (2008) Bmp2 signaling regulates the hepatic versus pancreatic fate decision. Developmental Cell. 15(5):738-748
Shin, C.H., Chung, W.S., Hong, S.K., Ober, E.A., Verkade, H., Field, H.A., Huisken, J., and Stainier, D.Y. (2008) Multiple roles for Med12 in vertebrate endoderm development. Developmental Biology. 317(2):467-479
Shin, D., Shin, C.H., Tucker, J., Ober, E.A., Rentzsch, F., Poss, K.D., Hammerschmidt, M., Mullins, M.C., and Stainier, D.Y. (2007) Bmp and Fgf signaling are essential for liver specification in zebrafish. Development (Cambridge, England). 134(11):2041-2050

Hand2 function in second heart field progenitors is essential for cardiogenesis.
Tsuchihashi T, Maeda J, Shin CH, Ivey KN, Black BL, Olson EN, Yamagishi H, Srivastava D.
Dev Biol. 2011 Mar 1;351(1):62-69.

HOP/NECC1, a novel regulator of mouse trophoblast differentiation.
Asanoma K, Kato H, Yamaguchi S, Shin CH, Liu ZP, Kato K, Inoue T, Miyanari Y, Yoshikawa K, Sonoda K, Fukushima K, Wake N.
J Biol Chem. 2007 Aug 17;282(33):24065-74.

Regulation of cardiac growth and development by SRF and its cofactors.
Wang D, Passier R, Liu ZP, Shin CH, Wang Z, Li S, Sutherland LB, Small E, Krieg PA, Olson EN.
Cold Spring Harb Symp Quant Biol. 2002;67:97-105.

Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.
Shin CH, Liu ZP, Passier R, Zhang CL, Wang DZ, Harris TM, Yamagishi H, Richardson JA, Childs G, Olson EN.
Cell. 2002 Sep 20;110(6):725-35.

Helical periodicity of GA-alternating triple-stranded DNA.
Shin C, Koo HS.
Biochemistry. 1996 Jan 23;35(3):968-72.