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Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-110131-2
Czopka, Tim
Email: tim.czopka@tum.de
URL: http://www.czopka-lab.de/
Affiliation: Tim Czopka Lab
Address: Institute of Neuronal Cell Biology Technical University of Munich Biedersteiner Str 29 80802 München Germany
Country: Germany
Phone: +49 89 4140 3377
Fax:
Orcid ID: 0000-0002-6824-8112


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Almeida, R.G., Pan, S., Cole, K.L.H., Williamson, J.M., Early, J.J., Czopka, T., Klingseisen, A., Chan, J.R., Lyons, D.A. (2018) Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand. Current biology : CB. 28(8):1296-1305.e5
Auer, F., Vagionitis, S., Czopka, T. (2018) Evidence for Myelin Sheath Remodeling in the CNS Revealed by In Vivo Imaging. Current biology : CB. 28(4):549-559.e3
Vagionitis, S., Czopka, T. (2018) Visualization and Time-Lapse Microscopy of Myelinating Glia In Vivo in Zebrafish. Methods in molecular biology (Clifton, N.J.). 1791:25-35
Czopka, T. (2016) Insights into mechanisms of central nervous system myelination using zebrafish. Glia. 64(3):333-49
Nawaz, S., Sánchez, P., Schmitt, S., Snaidero, N., Mitkovski, M., Velte, C., Brückner, B.R., Alexopoulos, I., Czopka, T., Jung, S.Y., Rhee, J.S., Janshoff, A., Witke, W., Schaap, I.A., Lyons, D.A., Simons, M. (2015) Actin filament turnover drives leading edge growth during myelin sheath formation in the central nervous system. Developmental Cell. 34:139-51
Mensch, S., Baraban, M., Almeida, R., Czopka, T., Ausborn, J., El Manira, A., Lyons, D. A. (2015) Synaptic vesicle release regulates myelin sheath number of individual oligodendrocytes in vivo. Nature Neuroscience. 18:628-630
Czopka, T., Ffrench-Constant, C., and Lyons, D.A. (2013) Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo. Developmental Cell. 25(6):599-609
Almeida, R.G., Czopka, T., Ffrench-Constant, C., and Lyons, D.A. (2011) Individual axons regulate the myelinating potential of single oligodendrocytes in vivo. Development (Cambridge, England). 138(20):4443-50
Czopka, T., and Lyons, D.A. (2011) Dissecting mechanisms of myelinated axon formation using zebrafish. Methods in cell biology. 105:25-62

NON-ZEBRAFISH PUBLICATIONS
Czopka T, von Holst A, ffrench-Constant C, Faissner A (2010) Regulatory mechanisms that mediate Tenascin C-dependent inhibition of oligodendrocyte precursor differentiation. J Neurosci 30(37): 12310-12322

Czopka T, Hennen E, von Holst A, Faissner A (2009) Novel conserved oligodendrocyte surface epitope identified by monoclonal antibody 4860. Cell Tissue Res 338(2): 161-170

Czopka T, von Holst A, Schmidt G, ffrench-Constant C, Faissner A (2009) Tenascin C and Tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway. Glia 57(16): 1790-1801