ZFIN ID: ZDB-PERS-101215-4
Newman, Morgan
Email: morgan.newman@adelaide.edu.au
URL:
Affiliation: Lardelli Lab
Address: School of Molecular and Biomedical Science The University of Adelaide Adelaide , 5005 Australia
Country: Australia
Phone: +61 8 83034863
Fax:
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Barthelson, K., Pederson, S.M., Newman, M., Lardelli, M. (2020) Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer's disease. Molecular brain. 13:142
Jiang, H., Pederson, S.M., Newman, M., Dong, Y., Barthelson, K., Lardelli, M. (2020) Transcriptome analysis indicates dominant effects on ribosome and mitochondrial function of a premature termination codon mutation in the zebrafish gene psen2. PLoS One. 15:e0232559
Hin, N., Newman, M., Kaslin, J., Douek, A.M., Lumsden, A., Nik, S.H.M., Dong, Y., Zhou, X.F., Mañucat-Tan, N.B., Ludington, A., Adelson, D.L., Pederson, S., Lardelli, M. (2020) Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2. PLoS One. 15:e0227258
van Eyk, C.L., Corbett, M.A., Frank, M.S.B., Webber, D.L., Newman, M., Berry, J.G., Harper, K., Haines, B.P., McMichael, G., Woenig, J.A., MacLennan, A.H., Gecz, J. (2019) Targeted resequencing identifies genes with recurrent variation in cerebral palsy. NPJ genomic medicine. 4:27
Newman, M., Hin, N., Pederson, S., Lardelli, M. (2019) Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Molecular brain. 12:43
Corbett, M.A., van Eyk, C.L., Webber, D.L., Bent, S.J., Newman, M., Harper, K., Berry, J.G., Azmanov, D.N., Woodward, K.J., Gardner, A.E., Slee, J., Pérez-Jurado, L.A., MacLennan, A.H., Gecz, J. (2018) Pathogenic copy number variants that affect gene expression contribute to genomic burden in cerebral palsy. NPJ genomic medicine. 3:33
Jiang, H., Newman, M., Lardelli, M. (2018) The zebrafish orthologue of familial Alzheimer's disease gene PRESENILIN 2 is required for normal adult melanotic skin pigmentation. PLoS One. 13:e0206155
Ratnayake, D., Newman, M., Lardelli, M. (2018) Degenerate codon mixing for PCR-based manipulation of highly repetitive sequences. BMC research notes. 11:202
Ebrahimie, E., Fruzangohar, M., Moussavi Nik, S.H., Newman, M. (2017) Gene Ontology-Based Analysis of Zebrafish Omics Data Using the Web Tool Comparative Gene Ontology. Zebrafish. 14(5):492-494
Newman, M., Halter, L., Lim, A., Lardelli, M. (2017) Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease. PLoS One. 12:e0179859
Hubbard, J.M., Böhm, U.L., Prendergast, A., Tseng, P.B., Newman, M., Stokes, C., Wyart, C. (2016) Intraspinal Sensory Neurons Provide Powerful Inhibition to Motor Circuits Ensuring Postural Control during Locomotion. Current biology : CB. 26(21):2841-2853
Ebrahimie, E., Moussavi-Nik, S.H., Newman, M., Van Der Hoek, M., Lardelli, M. (2016) The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress. Journal of Alzheimer's disease : JAD. 52(2):581-608
Moussavi-Nik, S.H., Newman, M., Wilson, L., Ebrahimie, E., Wells, S., Musgrave, I., Verdile, G., Martins, R.N., Lardelli, M. (2015) Alzheimer's disease-related peptide PS2V plays ancient, conserved roles in suppression of the unfolded protein response under hypoxia and stimulation of γ-secretase activity. Human molecular genetics. 24(13):3662-78
Moussavi Nik, S.H., Newman, M., Ganesan, S., Chen, M., Martins, R., Verdile, G., Lardelli, M. (2014) Hypoxia alters expression of Zebrafish Microtubule-associated protein Tau (mapta, maptb) gene transcripts. BMC research notes. 7:767
Ganesan, S., Moussavi Nik, S.H., Newman, M., Lardelli, M. (2014) Identification and expression analysis of the zebrafish orthologues of mammalian MAP1LC3 gene family. Experimental cell research. 328(1):228-37
Newman, M., Ebrahimie, E., Lardelli, M. (2014) Using the zebrafish model for Alzheimer's disease research. Frontiers in genetics. 5:189
Newman, M., Wilson, L., Verdile, G., Lim, A., Khan, I., Moussavi Nik, S.H., Pursglove, S., Chapman, G., Martins, R.N., and Lardelli, M. (2014) Differential, dominant activation and inhibition of Notch signalling and APP cleavage by truncations of PSEN1 in human disease. Human molecular genetics. 23(3):602-17
Newman, M., Nornes, S., Martins, R.N., and Lardelli, M.T. (2012) Robust homeostasis of Presenilin1 protein levels by transcript regulation. Neuroscience letters. 519(1):14-19
Nik, S.H., Wilson, L., Newman, M., Croft, K., Mori, T.A., Musgrave, I., and Lardelli, M. (2012) The BACE1-PSEN-AbetaPP Regulatory Axis has an Ancient Role in Response to Low Oxygen/Oxidative Stress. Journal of Alzheimer's disease : JAD. 28(3):515-530
Avdesh, A., Martin-Iverson, M.T., Mondal, A., Chen, M., Askraba, S., Newman, M., Lardelli, M., Groth, D.M., Verdile, G., and Martins, R.N. (2012) Evaluation of Color Preference in Zebrafish for Learning And Memory. Journal of Alzheimer's disease : JAD. 28(2):459-469
Moussavi Nik, S.H., Newman, M., and Lardelli, M. (2011) The response of HMGA1 to changes in oxygen availability is evolutionarily conserved. Experimental cell research. 317(11):1503-1512
Newman, M., Verdile, G., Martins, R.N., and Lardelli, M. (2011) Zebrafish as a tool in Alzheimer's disease research. Biochimica et biophysica acta. Molecular basis of disease. 1812(3):346-352
Newman, M., and Lardelli, M. (2010) A hyperactive sleeping beauty transposase enhances transgenesis in zebrafish embryos. BMC research notes. 3:282
Newman, M., Wilson, L., Camp, E., Verdile, G., Martins, R., and Lardelli, M. (2010) A zebrafish melanophore model of amyloid beta toxicity. Zebrafish. 7(2):155-159
Nornes, S., Newman, M., Wells, S., Verdile, G., Martins, R.N., and Lardelli, M. (2009) Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos. Experimental cell research. 315(16):2791-2801
Newman, M., Tucker, B., Nornes, S., Ward, A., and Lardelli, M. (2009) Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in Alzheimer's disease pathogenesis. Journal of Alzheimer's disease : JAD. 16(1):133-147
Nornes, S., Newman, M., Verdile, G., Wells, S., Stoick-Cooper, C., Tucker, B., Frederich-Sleptsova, I., Martins, R., and Lardelli, M. (2008) Interference with splicing of Presenilin transcripts has potent dominant negative effects on Presenilin activity. Human molecular genetics. 17(3):402-412
Newman, M., Musgrave, F.I., and Lardelli, M. (2007) Alzheimer disease: Amyloidogenesis, the presenilins and animal models. Biochimica et biophysica acta. Molecular basis of disease. 1772(3):285-297

NON-ZEBRAFISH PUBLICATIONS