ZFIN Person: Jacob, Vinitha

ZFIN ID: ZDB-PERS-101109-8

Jacob, Vinitha

Email:	vinitha.jacob@mssm.edu
URL:
Affiliation:
Address:	Sadler Research Laboratory Department of Medicine ~ Division of Liver Disease Department of Developmental and Regenerative Biology Mount Sinai School of Medicine One Gustave L. Levy Place New York, NY 10029-6574 USA
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ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Chernyavskaya, Y., Mudbhary, R., Tokarz, D., Jacob, V., Gopinath, S., Zhang, C., Sun, X., Wang, S., Magnani, E., Madakashira, B.P., Yoder, J.A., Hoshida, Y., Sadler, K.C. (2017) Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development (Cambridge, England). 144(16):2925-2939

Jacob, V., Chernyavskaya, Y., Chen, X., Tan, P.S., Kent, B., Hoshida, Y., Sadler, K.C. (2015) DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos. Development (Cambridge, England). 142(3):510-21

Mudbhary, R., Hoshida, Y., Chernyavskaya, Y., Jacob, V., Villanueva, A., Fiel, M.I., Chen, X., Kojima, K., Thung, S., Bronson, R.T., Lachenmayer, A., Revill, K., Alsinet, C., Sachidanandam, R., Desai, A., SenBanerjee, S., Ukomadu, C., Llovet, J.M., and Sadler, K.C. (2014) UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma. Cancer Cell. 25(2):196-209

Chu, J., Loughlin, E.A., Gaur, N.A., Senbanerjee, S., Jacob, V., Monson, C., Kent, B., Oranu, A., Ding, Y., Ukomadu, C., and Sadler, K.C. (2012) UHRF1 phosphorylation by Cyclin A2/CDK2 is required for zebrafish embryogenesis. Molecular biology of the cell. 23(1):59-70

NON-ZEBRAFISH PUBLICATIONS