ZFIN Person: Saxena, Ankur

ZFIN ID: ZDB-PERS-090219-1

ZFIN ID: ZDB-PERS-090219-1

Saxena, Ankur

Email:	asaxena1@uab.edu
URL:	https://www.saxenalab.com/
Affiliation:	Ankur Saxena
Address:	1918 University Blvd MCLM 914 Birmingham, AL 35233
Country:	United States
Phone:	2059969736
Fax:
ORCID ID:	0000-0001-8646-2887

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Ibarra, B.A., Jiang, X., Treffy, R.W., Saxena, A. (2022) Injection of human neuroblastoma cells into neural crest streams in live zebrafish embryos. STAR protocols. 3:101380

Treffy, R.W., Rajan, S.G., Jiang, X., Nacke, L.M., Malkana, U.A., Naiche, L.A., Bergey, D.E., Santana, D., Rajagopalan, V., Kitajewski, J.K., O'Bryan, J.P., Saxena, A. (2021) Neuroblastoma differentiation in vivo excludes cranial tumors. Developmental Cell. 56(19):2752-2764.e6

Rajan, S.G., Nacke, L.M., Dhingra, J.S., Saxena, A. (2021) Notch signaling mediates olfactory multiciliated cell specification. Cells & development. 168:203715

Condren, A.R., Costa, M.S., Sanchez, N.R., Konkapaka, S., Gallik, K.L., Saxena, A., Murphy, B.T., Sanchez, L.M. (2020) Addition of insoluble fiber to isolation media allows for increased metabolite diversity of lab-cultivable microbes derived from zebrafish gut samples. Gut microbes. 11(4):1064-1076

Rajan, S.G., Gallik, K.L., Monaghan, J.R., Uribe, R.A., Bronner, M.E., Saxena, A. (2018) Tracking neural crest cell cycle progression in vivo. Genesis (New York, N.Y. : 2000). 56(6-7):e23214

Suarez-Bregua, P., Saxena, A., Bronner, M.E., Rotllant, J. (2017) Targeted Pth4-expressing cell ablation impairs skeletal mineralization in zebrafish. PLoS One. 12:e0186444

Szabo, M., Svensson Akusjärvi, S., Saxena, A., Liu, J., Chandrasekar, G., Kitambi, S.S. (2017) Cell and small animal models for phenotypic drug discovery. Drug design, development and therapy. 11:1957-1967

Suarez-Bregua, P., Torres-Nuñez, E., Saxena, A., Guerreiro, P., Braasch, I., Prober, D.A., Moran, P., Cerda-Reverter, J.M., Du, S.J., Adrio, F., Power, D.M., Canario, A.V., Postlethwait, J.H., Bronner, M.E., Cañestro, C., Rotllant, J. (2017) Pth4, an ancient parathyroid hormone lost in eutherian mammals, reveals a new brain-to-bone signaling pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31:569-583

Saxena, A., Bronner, M.E. (2014) A novel HoxB cluster protein expressed in the hindbrain and pharyngeal arches. Genesis (New York, N.Y. : 2000). 52(10):858-63

Wang, K., Milkie, D.E., Saxena, A., Engerer, P., Misgeld, T., Bronner, M.E., Mumm, J., Betzig, E. (2014) Rapid adaptive optical recovery of optimal resolution over large volumes. Nature Methods. 11(6):625-8

Saxena, A., Peng, B.N., and Bronner, M.E. (2013) Sox10-dependent neural crest origin of olfactory microvillous neurons in zebrafish. eLIFE. 2:e00336

Trinh, A., Hochgreb, T., Graham, M., Wu, D., Ruf-Zamojski, F., Jayasena, C.S., Saxena, A., Hawk, R., Gonzalez-Serricchio, A., Dixson, A., Chow, E., Gonzales, C., Leung, H.Y., Solomon, I., Bronner-Fraser, M., Megason, S.G., and Fraser, S.E. (2011) A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Genes & Development. 25(21):2306-20

NON-ZEBRAFISH PUBLICATIONS
Maier EC, Saxena A, Alsina B, Bronner ME, Whitfield TT. Sensational placodes: Neurogenesis in the otic and olfactory systems. Developmental Biology (Cover Image), 389(1), 50-67 (2014).

Rogers CD, Saxena A, Bronner ME. Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT. J. of Cell Biology (Cover Image; Highlighted), 203(5), 835-47 (2013).

Saxena A & Tabin CJ. The miRNA-processing enzyme Dicer is necessary for cardiac outflow tract alignment and chamber septation. Proc. Natl. Acad. Sci. USA, 107(1), 87-91 (2010).

Saxena A, Fish JE, White MD, Yu S, Smyth JWP, Shaw RM, DiMaio JM, Srivastava D. Stromal cell-derived factor-1 alpha is cardioprotective during myocardial infarction. Circulation, 117(17), 2224-31 (2008).

Srivastava D, Saxena A, DiMaio JM, Bock-Marquette I. Thymosin B4 is cardioprotective after myocardial infarction. Ann. N.Y. Acad. Sci., 1112, 161-170 (2007).

Gao J*, Lee K*, Zhao M, Qiu J, Zhan X, Saxena A, Moore CJ, Cohen SN, Georgiou G. Differential modulation of E. coli mRNA abundance by inhibitory proteins that alter the composition of the degradosome. Molecular Microbiology, 61(2), 394-406 (2006).

Bock-Marquette I*, Saxena A*, White MD, DiMaio JM, Srivastava D. Thymosin B4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature (Article; Highlighted), 432(7016), 466-72 (2004).

Cowan CA*, Yokoyama N*, Saxena A, Chumley MJ, Silvany RE, Baker LA, Srivastava D, Henkemeyer M. Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Developmental Biology, 271(2), 263-71 (2004).