ZFIN Person: Lehmann, Ordan J.

ZFIN ID: ZDB-PERS-080527-1

Lehmann, Ordan J.

Email:	olehmann@ualberta.ca
URL:
Affiliation:	Lehmann Lab
Address:	Associate Professor, Depts. of Ophthalmology and Medical Genetics Canada Research Chair and AHFMR Clinical Investigator 8-29 Medical Sciences Building University of Alberta Edmonton, Alberta, T6G 2H7 Canada
Country:	Canada
Phone:	001-780-492-8550
Fax:	001-780-492-6934
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Fox, S.C., Widen, S.A., Asai-Coakwell, M., Havrylov, S., Benson, M., Prichard, L.B., Baddam, P., Graf, D., Lehmann, O.J., Waskiewicz, A.J. (2022) BMP3 is a novel locus involved in the causality of ocular coloboma. Human genetics. 141(8):1385-1407

Chrystal, P.W., French, C.R., Jean, F., Havrylov, S., van Baarle, S., Peturson, A.M., Xu, P., Crump, J.G., Pilgrim, D.B., Lehmann, O.J., Waskiewicz, A.J. (2021) The Axenfeld-Rieger Syndrome Gene FOXC1 Contributes to Left-Right Patterning. Genes. 12(2):

Whitesell, T.R., Chrystal, P.W., Ryu, J.R., Munsie, N., Grosse, A., French, C.R., Workentine, M.L., Li, R., Zhu, L.J., Waskiewicz, A., Lehmann, O.J., Lawson, N.D., Childs, S.J. (2019) foxc1 is required for embryonic head vascular smooth muscle differentiation in zebrafish. Developmental Biology. 453(1):34-47

Lahola-Chomiak, A.A., Footz, T., Nguyen-Phuoc, K., Neil, G.J., Fan, B., Allen, K.F., Greenfield, D.S., Parrish, R.K., Linkroum, K., Pasquale, L.R., Leonhardt, R.M., Ritch, R., Javadiyan, S., Craig, J.E., Ted Allison, W., Lehmann, O.J., Walter, M.A., Wiggs, J.L. (2018) Non-Synonymous variants in Premelanosome Protein (PMEL) cause ocular pigment dispersion and pigmentary glaucoma. Human molecular genetics. 28(8):1298-1311

Hocking, J.C., Famulski, J.K., Yoon, K.H., Widen, S.A., Bernstein, C.S., Koch, S., Weiss, O., FORGE Canada Consortium, Agarwala, S., Inbal, A., Lehmann, O.J., Waskiewicz, A.J. (2018) Morphogenetic defects underlie Superior Coloboma, a newly identified closure disorder of the dorsal eye. PLoS Genetics. 14:e1007246

Liu, C., Widen, S.A., Williamson, K.A., Ratnapriya, R., Gerth-Kahlert, C., Rainger, J., Alur, R.P., Strachan, E., Manjunath, S.H., Balakrishnan, A., Floyd, J.A., Li, T., Waskiewicz, A., Brooks, B.P., Lehmann, O.J., FitzPatrick, D.R., Swaroop, A. (2016) A secreted WNT-ligand-binding domain of FZD5 generated by a frameshift mutation causes autosomal dominant coloboma. Human molecular genetics. 25(7):1382-91

French, C.R., Seshadri, S., Destefano, A.L., Fornage, M., Arnold, C.R., Gage, P.J., Skarie, J.M., Dobyns, W.B., Millen, K.J., Liu, T., Dietz, W., Kume, T., Hofker, M., Emery, D.J., Childs, S.J., Waskiewicz, A.J., Lehmann, O.J. (2014) Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease. J. Clin. Invest.. 124(11):4877-81

Pillai-Kastoori, L., Wen, W., Wilson, S.G., Strachan, E., Lo-Castro, A., Fichera, M., Musumeci, S.A., Lehmann, O.J., Morris, A.C. (2014) Sox11 Is Required to Maintain Proper Levels of Hedgehog Signaling during Vertebrate Ocular Morphogenesis. PLoS Genetics. 10:e1004491

Pant, S.D., March, L.D., Famulski, J.K., French, C.R., Lehmann, O.J., and Waskiewicz, A.J. (2013) Molecular mechanisms regulating ocular apoptosis in zebrafish gdf6a mutants. Investigative ophthalmology & visual science. 54(8):5871-5879

French, C.R., Stach, T.R., March, L.D., Lehmann, O.J., and Waskiewicz, A.J. (2013) Apoptotic and proliferative defects characterize ocular development in a microphthalmic BMP model. Investigative ophthalmology & visual science. 54(7):4636-4647

Duval, M.G., Chung, H., Lehmann, O.J., and Allison, W.T. (2013) Longitudinal fluorescent observation of retinal degeneration and regeneration in zebrafish using fundus lens imaging. Molecular Vision. 19:1082-1095

Asai-Coakwell, M., March, L., Dai, X.H., Duval, M., Lopez, I., French, C.R., Famulski, J., De Baere, E., Francis, P.J., Sundaresan, P., Sauvé, Y., Koenekoop, R.K., Berry, F.B., Allison, W.T., Waskiewicz, A.J., and Lehmann, O.J. (2013) Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies. Human molecular genetics. 22(7):1432-1442

Ye, M., Berry-Wynne, K.M., Asai-Coakwell, M., Sundaresan, P., Footz, T., French, C.R., Abitbol, M., Fleisch, V.C., Corbett, N., Allison, W.T., Drummond, G., Walter, M.A., Underhill, T.M., Waskiewicz, A.J., and Lehmann, O.J. (2010) Mutation of the Bone Morphogenetic Protein GDF3 causes ocular and skeletal anomalies. Human molecular genetics. 19(2):287-298

Asai-Coakwell, M., French, C.R., Ye, M., Garcha, K., Bigot, K., Perera, A.G., Staehling-Hampton, K., Mema, S.C., Chanda, B., Mushegian, A., Bamforth, S., Doschak, M.R., Li, G., Dobbs, M.B., Giampietro, P.F., Brooks, B.P., Vijayalakshmi, P., Sauvé, Y., Abitbol, M., Sundaresan, P., Heyningen, V.V., Pourquié, O., Underhill, T.M., Waskiewicz, A.J., and Lehmann, O.J. (2009) Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes. Human molecular genetics. 18(6):1110-1121

Asai-Coakwell, M., French, C.R., Berry, K.M., Ye, M., Koss, R., Somerville, M., Mueller, R., van Heyningen, V., Waskiewicz, A.J., and Lehmann, O.J. (2007) GDF6, a novel locus for a spectrum of ocular developmental anomalies. American journal of human genetics. 80(2):306-315

NON-ZEBRAFISH PUBLICATIONS