ZFIN Person: Georlette, Daphne

ZFIN ID: ZDB-PERS-080519-1

ZFIN ID: ZDB-PERS-080519-1

Georlette, Daphne

Email:	daph@temple.edu
URL:
Affiliation:	Biemar Lab
Address:	Department of Biology Temple University 439 Biology Life Sciences Building 1900 North 12th Street Philadelphia, PA 19122 USA
Country:	United States
Phone:	215-204-1925
Fax:	215-204-6646
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

Gene regulatory network regulating pancreas formation and endocrine cell differentiation.

PUBLICATIONS

Balciuniene, J., Nagelberg, D., Walsh, K., Camerota, D., Georlette, D., Biemar, F., Bellipanni, G., and Balciunas, D. (2013) Efficient disruption of Zebrafish genes using a Gal4-containing gene trap. BMC Genomics. 14(1):619

Verbruggen, V., Ek, O., Georlette, D., Delporte, F., Von Berg, V., Detry, N., Biemar, F., Coutinho, P., Martial, J.A., Voz, M.L., Manfroid, I., and Peers, B. (2010) The Pax6b homeodomain is dispensable for pancreatic endocrine cell differentiation in zebrafish. The Journal of biological chemistry. 285(18):13863-13873

NON-ZEBRAFISH PUBLICATIONS
Georlette D, Ahn S, MacAlpine DM, Cheung E, Lewis PW, Beall EL, Bell SP, Speed T, Manak JR, Botchan MR. Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cells. Genes Dev. 2007 Nov 15;21(22):2880-96. Epub 2007 Oct 31.

Lewis PW, Beall EL, Fleischer TC, Georlette D, Link AJ, Botchan MR. Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex. Genes Dev. 2004 Dec 1;18(23):2929-40. Epub 2004 Nov 15.

Beall EL, Bell M, Georlette D, Botchan MR. Dm-myb mutant lethality in Drosophila is dependent upon mip130: positive and negative regulation of DNA replication.
Genes Dev. 2004 Jul 15;18(14):1667-80.

Georlette D, Blaise V, Collins T, D'Amico S, Gratia E, Hoyoux A, Marx JC, Sonan G, Feller G, Gerday C. Some like it cold: biocatalysis at low temperatures. FEMS Microbiol Rev. 2004 Feb;28(1):25-42. Review.

Georlette D, Blaise V, Bouillenne F, Damien B, Thorbjarnardóttir SH, Depiereux E, Gerday C, Uversky VN, Feller G. Adenylation-dependent conformation and unfolding pathways of the NAD+-dependent DNA ligase from the thermophile Thermus scotoductus. Biophys J. 2004 Feb;86(2):1089-104.

Georlette D, Blaise V, Dohmen C, Bouillenne F, Damien B, Depiereux E, Gerday C, Uversky VN, Feller G. Cofactor binding modulates the conformational stabilities and unfolding patterns of NAD(+)-dependent DNA ligases from Escherichia coli and Thermus scotoductus. J Biol Chem. 2003 Dec 12;278(50):49945-53. Epub 2003 Sep 30.

Georlette D, Damien B, Blaise V, Depiereux E, Uversky VN, Gerday C, Feller G. Structural and functional adaptations to extreme temperatures in psychrophilic, mesophilic, and thermophilic DNA ligases. J Biol Chem. 2003 Sep 26;278(39):37015-23. Epub 2003 Jul 10.

Georlette D, Jónsson ZO, Van Petegem F, Chessa J, Van Beeumen J, Hübscher U, Gerday C. A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperatures. Eur J Biochem. 2000 Jun;267(12):3502-12.