ZFIN ID: ZDB-PERS-080111-9
Gupta, Dipika
Email: dgupta@iun.edu
URL:
Affiliation: Gupta Lab
Address: Assistant Professor of Biochemistry and Molecular Biology Indiana University School of Medicine Northwest 3400 Broadway Gary, IN 46408 USA
Country: United States
Phone: 219-980-6557
Fax: 219-980-6566
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Li, X., Wang, S., Qi, J., Echtenkamp, S.F., Chatterjee, R., Wang, M., Boons, G.J., Dziarski, R., and Gupta, D. (2007) Zebrafish Peptidoglycan Recognition Proteins Are Bactericidal Amidases Essential for Defense against Bacterial Infections. Immunity. 27(3):518-29

NON-ZEBRAFISH PUBLICATIONS
Liu, C., Xu, Z., Gupta, D., and Dziarski, R. (2001). Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules. Journal of Biological Chemistry, 276:34355-35222 (featured on the cover of September 14 issue), PMID: 11461926.

Xu, Z., Dziarski, R., Wang, Q., Swartz, K., Sakamoto, K.M., and Gupta, D. (2001). Bacterial peptidoglycan-induced tnf-α transcription is mediated through the transcription factors Egr-1, Elk-1, and NF-κB. Journal of Immunology, 167:6975-6982, PMID: 11739517.

Dziarski, R., Platt, K.A., Gelius, E., Steiner, H., and Gupta, D. (2003). Defect in neutrophil killing and increased susceptibility to infection with non-pathogenic Gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)-deficient mice. Blood, 102: 689-697 (featured in an editorial: Inside Blood), PMID: 12649138.

Wang, Z-M., Li, X., Cocklin, R.R., Wang, M., Wang, M., Fukase, K., Inamura, S., Kusumoto, K., Gupta, D., and Dziarski, R. (2003). Human peptidoglycan recognition protein-L (PGRP-L) is an N-acetylmuramoyl-L-alanine amidase. Journal of Biological Chemistry, 278:49044-49052, PMID: 14506276.

Dziarski, R., and Gupta, D. (2005). Staphylococcus aureus peptidoglycan is a Toll-like receptor 2 activator: a reevaluation. Infection and Immunity, 73:5212-5216, PMID: 16041042.

Zhang, Y., van der Fits, L., Voerman, J.S., Melief, M-J., Laman, J.D., Wang, M., Wang, H., Wang, M., Li, X., Walls, C.D., Gupta, D., and Dziarski, R. (2005). Identification of serum N-acetylmuramoyl-L-alanine amidase as liver peptidoglycan recognition protein 2. Biochimica et Biophysica Acta – Proteins and Proteomics, 1752:34-46, PMID: 16054449.

Wang, H., Gupta, D., Li, X., and Dziarski, R. (2005). Peptidoglycan recognition protein 2 (N-acetylmuramoyl-L-ala amidase) is induced in keratinocytes by bacteria through p38 kinase pathway. Infection and Immunity, 73:7216-7225, PMID: 16239516.

Lu, X., Wang, M., Qi, J., Wang, H., Li, X., Gupta, D., and Dziarski, R. (2006). Peptidoglycan recognition proteins are a new class of human bactericidal proteins. Journal of Biological Chemistry, 281:5895-5907, PMID: 16354652.

Li, X., Wang, S., Wang, H., and Gupta, D. (2006). Differential expression of peptidoglycan recognition protein 2 in the skin and liver requires different transcription factors. Journal of Biological Chemistry, 281:20738-20748, PMID: 16714290.

Wang M., Liu L.H., Wang S., Li X., Lu X., Gupta D., and Dziarski R. (2007). Human peptidoglycan recognition proteins require zinc to kill both gram-positive and gram-negative bacteria and are synergistic with antibacterial peptides. Journal of Immunology, 178:3116-3125, PMID: 17312159.