Biography and Research Interest

Regulation of the Nodal signaling pathway

Publications

Non-Zebrafish Publications

Haffner C., Dettmer U., Weiler T. and Haass C. (2007) The Nicastrin-like
Protein Nicalin Regulates Assembly and
Stability of the Nicalin-Nodal Modulator (NOMO) Membrane Protein Complex. J.
Biol. Chem.. 282 (14): 10632-10638

Krawitz, P., Haffner, C., Fluhrer, R., Steiner, H., Schmid, B., and Haass,
C. (2005) Differential localization and identification of a critical
aspartate suggest non-redundant proteolytic functions of the presenlin in
homologues SPPL2b and SPPL3. J. Biol. Chem.. 280(47):39515-39523

Haffner, C., and Haass, C. (2004) The Biochemical and Genetic Odyssey to the
Function of a Nicastrin-Like Protein. Neurodegener. Dis.. 1(4-5):192-195


Haffner, C., Frauli, M., Topp, S., Irmler, M., Hofmann, K., Regula, J.T.,
Bally-Cuif, L., and Haass, C. (2004) Nicalin and its binding partner Nomo
are novel Nodal signaling antagonists. EMBO J.. 23(15):3041-3050