ZFIN Person: von Hofsten, Jonas

ZFIN ID: ZDB-PERS-061221-1

ZFIN ID: ZDB-PERS-061221-1

von Hofsten, Jonas

Email:	jonas.von.hofsten@ucmm.umu.se
URL:	http://www.ucmm.umu.se/forskning/jonas-von-hofsten/
Affiliation:	von Hofsten Lab
Address:	Umeå Centre for Molecular Medicine Umeå University Analysvägen 1 90187 Umeå Sweden
Country:	United Kingdom
Phone:	+46 907854417
Fax:	+46 705825858
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Kahsay, A., Dennhag, N., Liu, J.X., Nord, H., Rönnbäck, H., Thorell, A.E., von Hofsten, J., Pedrosa Domellöf, F. (2024) Obscurin Maintains Myofiber Identity in Extraocular Muscles. Investigative ophthalmology & visual science. 65:1919

Deiana, M., Andrés Castán, J.M., Josse, P., Kahsay, A., Sánchez, D.P., Morice, K., Gillet, N., Ravindranath, R., Patel, A.K., Sengupta, P., Obi, I., Rodriguez-Marquez, E., Khrouz, L., Dumont, E., Abad Galán, L., Allain, M., Walker, B., Ahn, H.S., Maury, O., Blanchard, P., Le Bahers, T., Öhlund, D., von Hofsten, J., Monnereau, C., Cabanetos, C., Sabouri, N. (2023) A new G-quadruplex-specific photosensitizer inducing genome instability in cancer cells by triggering oxidative DNA damage and impeding replication fork progression. Nucleic acids research. 51(12):6264-6285

Kahsay, A., Rodriguez-Marquez, E., López-Pérez, A., Hörnblad, A., von Hofsten, J. (2022) Pax3 loss of function delays tumour progression in kRAS-induced zebrafish rhabdomyosarcoma models. Scientific Reports. 12:17149

Nord, H., Kahsay, A., Dennhag, N., Pedrosa Domellöf, F., von Hofsten, J. (2021) Genetic compensation between Pax3 and Pax7 in zebrafish appendicular muscle formation. Developmental Dynamics : an official publication of the American Association of Anatomists. 251(9):1423-1438

Dennhag, N., Liu, J.X., Nord, H., von Hofsten, J., Pedrosa Domellöf, F. (2020) Absence of Desmin in Myofibers of the Zebrafish Extraocular Muscles. Translational vision science & technology. 9:1

Nord, H., Dennhag, N., Tydinger, H., von Hofsten, J. (2019) The zebrafish HGF receptor met controls migration of myogenic progenitor cells in appendicular development. PLoS One. 14:e0219259

Aripaka, K., Gudey, S.K., Zang, G., Schmidt, A., Åhrling, S.S., Österman, L., Bergh, A., von Hofsten, J., Landström, M. (2019) TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer. EBioMedicine. 45:192-207

Dongre, M., Singh, B., Aung, K.M., Larsson, P., Miftakhova, R., Persson, K., Askarian, F., Johannessen, M., von Hofsten, J., Persson, J.L., Erhardt, M., Tuck, S., Uhlin, B.E., Wai, S.N. (2018) Flagella-mediated secretion of a novel Vibrio cholerae cytotoxin affecting both vertebrate and invertebrate hosts.. Communications biology. 1:59

Nord, H., Dennhag, N., Muck, J., von Hofsten, J. (2016) Pax7 is required for establishment of the xanthophore lineage in zebrafish embryos. Molecular biology of the cell. 27(11):1853-62

Nord, H., Burguiere, A.C., Muck, J., Nord, C., Ahlgren, U., and von Hofsten, J. (2014) Differential regulation of myosin heavy chains defines new muscle domains in zebrafish. Molecular biology of the cell. 25(8):1384-95

Nord, H., Skalman, L.N., and von Hofsten, J. (2013) Six1 regulates proliferation of Pax7-positive muscle progenitors in zebrafish. Journal of Cell Science. 126(Pt 8):1868-80

Burguière, A.C., Nord, H., and von Hofsten, J. (2011) Alkali-like myosin light chain-1 (myl1) is an early marker for differentiating fast muscle cells in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(7):1856-1863

von Hofsten, J., Elworthy, S., Gilchrist, M.J., Smith, J.C., Wardle, F.C., and Ingham, P.W. (2008) Prdm1- and Sox6-mediated transcriptional repression specifies muscle fibre type in the zebrafish embryo. EMBO reports. 9(7):683-689

von Hofsten, J., and Olsson, P.E. (2005) Zebrafish sex determination and differentiation: Involvement of FTZ-F1 genes. Reproductive Biology and Endocrinolgy. 3(1):63

Olsson, P.E., Berg, H., von Hofsten, J., Grahn, B., Hellqvist, A., Larsson, A., Karlsson, J., Modig, C,, Borg, B., and Thomas. P. (2005) Molecular cloning and characterization of a nuclear androgen receptor activated by 11-ketotestosterone. Reproductive Biology and Endocrinolgy. 3:37

von Hofsten, J., Larsson, A., and Olsson, P.E. (2005) Novel steroidogenic factor-1 homolog (ff1d) is coexpressed with anti-Mullerian hormone (AMH) in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 233(2):595-604

von Hofsten, J., Modig, C., Larsson, A., Karlsson, J., and Olsson, P.E. (2005) Determination of the expression pattern of the dual promoter of zebrafish fushi tarazu factor-1a following microinjections into zebrafish one cell stage embryos. General and comparative endocrinology. 142(1-2):222-226

O'Toole, R., von Hofsten, J., Rosqvist, R., Olsson, P.E., and Wolf-Watz, H. (2004) Visualisation of Zebrafish infection by GFP-labelled Vibrio anguillarum. Microbial pathogenesis. 37(1):41-46

Karlsson, J., von Hofsten, J., and Olsson, P.E. (2001) Generating transparent zebrafish: A refined method to improve detection of gene expression during embryonic development. Marine biotechnology (New York, N.Y.). 3(6):522-527

von Hofsten, J., Jones, I., Karlsson, J., and Olsson, P.E. (2001) Developmental expression patterns of FTZ-F1 homologues in zebrafish (Danio rerio). General and comparative endocrinology. 121(2):146-155

NON-ZEBRAFISH PUBLICATIONS
Maier E, von Hofsten J, Nord H, Fernandez M, Peak H, Hebert J, Gunhaga L. (2010) Opposing activities of FGF and BMP regulate the olfactory sensory versus respiratory epithelial cell fate decision. Development 137:1601-11

Maier E, Nord H, von Hofsten J, Gunhaga L. (2011) A balance of BMP and Notch activity regulates neurogenesis and olfactory nerve formation. Plos ONE 6(2):e17379

Ostrakhovitch EA, Olsson P-E, von Hofsten J, Cherian MG (2007) P53 Mediated regulation of metallothionein in breast cancer cells. J Cell Biochem. May 3; [Epub ahead of print]

Modig C, Modesto T, Canario A, Cerda J, von Hofsten J, Olsson PE. (2006) Molecular characterization and expression pattern of zona pellucida protein in gilthead seabream: Identification of the novel ZPX as a homologue to mammalian ZPA. Biol Reprod 75:717-25.

Olsson P-E,. Berg AH, von Hofsten J, Grahn B, Hellqvist A., Larsson A, Karlsson J, Modig C, Borg B, and Thomas P. (2005) Molecular cloning and characterization of a nuclear androgen receptor activated by 11-Ketotestosterone. Reprod Biol Endocrinol 17;3:37.

von Hofsten J, Karlsson J, Olsson P-E. (2003) Fushi tarazu factor-1 mRNA and protein is expressed in steroidogenic and cholesterol metabolising tissues during different life stages in Arctic char (Salvelinus alpinus) Gen Comp Endocrinol 132:96-102

von Hofsten J, Karlsson J, Jones I, Olsson P-E. (2002) Expression and regulation of fushi tarazu factor-1 and steroidogenic genes during reproduction in Arctic char (Salvelinus alpinus). Biol Reprod 67:1297-1304