ZFIN Person: Vernier, Philippe

ZFIN ID: ZDB-PERS-060905-1

ZFIN ID: ZDB-PERS-060905-1

Vernier, Philippe

Email:	philippe.vernier@inaf.cnrs-gif.fr
URL:	http://www.iaf.cnrs-gif.fr/eng/depsn/index.html
Affiliation:	Vernier Lab
Address:	Développement, Evolution, Plasticite du Systeme Nerveux, UPR2197 Institut de Neurobiologie Alfred Fessard C.N.R.S. Avenue de la Terrasse Gif-sur-Yvette, France
Country:	France
Phone:	33- (0)169 82 34 30
Fax:	33- (0)169 82 34 47
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Bataille, S., Jalaber, H., Colin, I., Remy, D., Affaticati, P., Froc, C., Levraud, J.P., Vernier, P., Demarque, M. (2023) Plasticity of dopaminergic phenotype and locomotion in larval zebrafish induced by brain excitability changes during the embryonic period. eNeuro. 10(6):

Xavier, A.L., Fontaine, R., Bloch, S., Affaticati, P., Jenett, A., Demarque, M., Vernier, P., Yamamoto, K. (2017) Comparative analysis of monoaminergic cerebrospinal fluid-contacting cells in Osteichthyes (bony vertebrates). The Journal of comparative neurology. 525(9):2265-2283

Faure, E., Savy, T., Rizzi, B., Melani, C., Stašová, O., Fabrèges, D., Špir, R., Hammons, M., Čúnderlík, R., Recher, G., Lombardot, B., Duloquin, L., Colin, I., Kollár, J., Desnoulez, S., Affaticati, P., Maury, B., Boyreau, A., Nief, J.Y., Calvat, P., Vernier, P., Frain, M., Lutfalla, G., Kergosien, Y., Suret, P., Remešíková, M., Doursat, R., Sarti, A., Mikula, K., Peyriéras, N., Bourgine, P. (2016) A workflow to process 3D+time microscopy images of developing organisms and reconstruct their cell lineage. Nature communications. 7:8674

Affaticati, P., Yamamoto, K., Rizzi, B., Bureau, C., Peyriéras, N., Pasqualini, C., Demarque, M., Vernier, P. (2015) Identification of the optic recess region as a morphogenetic entity in the zebrafish forebrain. Scientific Reports. 5:8738

von Trotha, J.W., Vernier, P., Bally-Cuif, L. (2014) Emotions and motivated behavior converge on an amygdala-like structure in the zebrafish. The European journal of neuroscience. 40(9):3302-3315

Yamamoto, K., Mirabeau, O., Bureau, C., Blin, M., Michon-Coudouel, S., Demarque, M., and Vernier, P. (2013) Evolution of dopamine receptor genes of the D1 class in vertebrates. Mol. Biol. Evol.. 30(4):833-843

Fontaine, R., Affaticati, P., Yamamoto, K., Jolly, C., Bureau, C., Baloche, S., Gonnet, F., Vernier, P., Dufour, S., and Pasqualini, C. (2013) Dopamine Inhibits Reproduction in Female Zebrafish (Danio rerio) via Three Pituitary D2 Receptor Subtypes. Endocrinology. 154(2):807-818

Lange, M., Norton, W., Coolen, M., Chaminade, M., Merker, S., Proft, F., Schmitt, A., Vernier, P., Lesch, K.P., and Bally-Cuif, L. (2012) The ADHD-linked gene Lphn3.1 controls locomotor activity and impulsivity in zebrafish. Molecular psychiatry. 17(9):855

Lange, M., Norton, W., Coolen, M., Chaminade, M., Merker, S., Proft, F., Schmitt, A., Vernier, P., Lesch, K.P., and Bally-Cuif, L. (2012) The ADHD-susceptibility gene lphn3.1 modulates dopaminergic neuron formation and locomotor activity during zebrafish development. Molecular psychiatry. 17(9):946-954

Kalueff, A.V., Stewart, A.M., Kyzar, E.J., Cachat, J., Gebhardt, M., Landsman, S., Robinson, K., Maximino, C., Herculano, A.M., Jesuthasan, S., Wisenden, B., Bally-Cuif, L., Lange, M., Vernier, P., Norton, W., Tierney, K., Tropepe, V., and Neuhauss, S. (2012) Time to recognize zebrafish ‘affective’ behavior. Behaviour. 149:1019-1036

Yamamoto, K., Ruuskanen, J.O., Wullimann, M.F., and Vernier, P. (2011) Differential expression of dopaminergic cell markers in the adult zebrafish forebrain. The Journal of comparative neurology. 519(3):576-598

Yamamoto, K., Ruuskanen, J.O., Wullimann, M.F., and Vernier, P. (2010) Two tyrosine hydroxylase genes in vertebrates: New dopaminergic territories revealed in the zebrafish brain. Molecular and cellular neurosciences. 43(4):394-402

Osório, J., Mueller, T., Rétaux, S., Vernier, P., and Wullimann, M.F. (2010) Phylotypic expression of the bHLH genes Neurogenin2, Neurod, and Mash1 in the mouse embryonic forebrain. The Journal of comparative neurology. 518(6):851-871

Blin, M., Norton, W., Bally-Cuif, L., and Vernier, P. (2008) NR4A2 controls the differentiation of selective dopaminergic nuclei in the zebrafish brain. Molecular and cellular neurosciences. 39(4):592-604

Mueller, T., Vernier, P., and Wullimann, M.F. (2006) A phylotypic stage in vertebrate brain development: GABA cell patterns in zebrafish compared with mouse. The Journal of comparative neurology. 494(4):620-634

Mueller, T., Vernier, P., and Wullimann, M.F. (2004) The adult central nervous cholinergic system of a neurogenetic model animal, the zebrafish Danio rerio. Brain research. 1011(2):156-169

NON-ZEBRAFISH PUBLICATIONS
Wullimann, M. and Vernier, P. (2006) Evolution of the Nervous System in Fishes. In Evolution of Nervous Systems, (J. Kaas, ed.) Elsevier, 5 Volumes.

Moret, F., Christiaen, L., Deyts, C., Blin, M., Joly, J-S. and Vernier, P. (2005) The dopamine-synthesizing cells of the sensory vesicle of the tunicate Ciona intestinalis are located only in a hypothalamus-related domain: implications for the origin of vertebrate catecholamine systems. Eur. J. Neurosci., 21: 3043-3055.

Moret, F., Christiaen, L., Deyts, C., Blin, M., Vernier, P. and Joly, J-S. (2005) Regulatory gene expressions in the ascidian ventral sensory vesicle: evolutionary relationships with the vertebrate hypothalamus. Dev. Biol. 277: 557-566.

Weltzien F-A., Pasqualini C., Vernier P. and Dufour S. (2005) A
quantitative real-time RT-PCR assay for European eel tyrosine
hydroxylase. Gen Comp Endocrinol. 142: 134-142.

Dufour S, Weltzien FA, Sebert ME, Le Belle N, Vidal B, Vernier P. and Pasqualini C. (2005) Dopaminergic inhibition of reproduction in teleost fishes: ecophysiological and evolutionary implications. Ann N Y Acad Sci. 1040: 9-21.

Fuentes, M., Schubert, M., Dalfo, D., Candiani, S., Benito, E., Gardenyes, J., Odoy, L., Moret, F., Illas, M., Patten, I., Permanyer, J., Oliveri, D., Boeuf, G., Falcon, J., Pestarino, M., Garcia-Fernandez, J., Albalat, R., Laudet, V., Vernier, P. and Escriva, E. (2004) Preliminary observations on the spawning conditions of the european amphioxus (Branchiostoma lanceolatum) in captivity. J Exp Zool. Part B Mol Dev Evol, 302:384-391.

Moret, F., Guilland, J-C., Coudouel, S., Rochette, L. and Vernier P. (2004) Distribution of tyrosine hydroxylase, dopamine and serotonin in the central nervous system of amphioxus (Branchiostoma lanceolatum): Implications for the evolution of catecholamine systems in vertebrates. J. Comp. Neurol.. 468: 135-150

Sidhu, A., Wersinger C., and Vernier, P., (2004) Does a-synuclein modulate dopaminergic synaptic content and tone at the synapse? (Review) FASEB J. 18: 637-47.

Sidhu, A., Wersinger C., and Vernier, P., (2004) a-synuclein regulation of the dopaminergic transporter: a possible role in the pathogenesis of Parkinson’s disease. (Review) FEBS lett., 265: 1-5.

Wersinger C, Vernier, P., and Sidhu, A. (2004) Trypsin disrupts trafficking of the human dopamine transporter by alpha-synuclein and its a30p mutant. Biochemistry 43: 1242-1253.

Le Crom, S., Sugamori, KS, Sidhu, A., Niznik, H.B. and Vernier, P. (2004) Delineation of the conserved functional properties of the D1A, D1B and D1C dopamine receptor subtypes in vertebrates. Biol. Cell, 96: 383-394.

Alunni, A., Blin, M., Deschet, K., Bourrat, F., Vernier, P. and Rétaux, S. (2004) Cloning and developmental expression patterns of Dlx2, Lhx7, and Lhx9 in the medaka fish (Oryzias latipes). Mech. Dev, 121: 977-983

Vernier, P., Callier, S., Moret, F., Snapyan, M., Wersinger, C. and Sidhu, A. (2004) The degeneration of dopamine neurons in Parkinson's disease : Insights from embryology and evolution of the meso-striato-cortical system. N.Y. Acad. Sci. 1035: 231-249.

Wersinger C, Prou, D., Vernier, P., Niznik H. B. and Sidhu, A. (2003) Mutations in the lipid-binding domain of a-synuclein confer overlapping, yet distinct, functional properties in the regulation of dopamine transporter activity. Mol. Cell Neurosci., 24: 91-105.

Wersinger C, Prou, D., Vernier, P. and Sidhu, A. (2003) Modulation of dopamine transporter function by a-synuclein is altered by cell adhesion impairment and oxydative stress. FASEB J. 17: Doi: 10.1096/fj.03-0152fje

Le Crom, S., Kapsimali, M. Barome, P.O. and Vernier, P. (2003) Dopamine receptors for every species: Gene duplications and functional diversification in Craniates (a review). J. Struct. Funct. Gen., 3: 161-176

Callier, S., Snapyan, M., Prou, D., Vincent J-D and Vernier, P. (2003) Evolution and cell biology of dopamine receptors. (Review) Biol. Cell 95: 489-502

Kapsimali, M., Le Crom, S. and Vernier, P. (2003) A natural history of vertebrate dopamine receptors. In : Dopamine receptors and transporters. M. Laruelle, A. Sidhu and P.Vernier (eds.) Marcel Dekker Inc., New York, pp. 1- 43.

Christiaen, L., Burighel, P., Smith, W.C., Vernier, P., Bourrat, F. and Joly, J-S. (2002) Pitx genes in tunicates provide new molecular insights in the evolutionary origin of the pituitary gland. Gene, 287:107-113

Le Crom, S., Prou, D. and Vernier, P. (2002) Autocrine activation of adenosine A1 receptors blocks D1A but not D1B dopamine receptor desensitization. J. Neurochem., 82:1549-1552.

Pasqualini, C., Guivarc’h, D., Barnier, J-V., Guibert, B., Vincent, J-D. and Vernier, P. (2001) Differential subcellular distribution and transcriptional activity of SE3, SE4 and SE3-4 isoforms of the rat estrogen receptor-a. Mol. Endocrinol., 15: 894-908.

König, S., Guibert, B., Morice, C., Vernier, P. and Barnier, J-V. (2001) Phosphorylation by PKA of a site unique to B-Raf. C.R. Acad. Sci. III, 324: 673-681.

Bachy, I., Vernier, P. and Retaux, S. (2001) The LIM-homeodomain gene family in the developping brain of Xenopus: Similarities and divergences with the mouse related to the evolution of the forebrain. J. Neurosci., 21: 7620-7629.

Gu, W-J., Prou, D., Le Crom, S., Maltais, S., Vincent, J-D., Salamero, J. and Vernier, P. (2001) Overexpression of the two isoforms of the D2 dopamine receptor disrupts endoplasmic reticulum in heterologous cells. J. Cell. Science, 114: 3517-3527.

Kapsimali, M., Bourrat, F. and Vernier, P. (2001) Distribution of the orphan nuclear receptor nurr1 in medaka (Oryzias latipes) : cues to the definition of homologous territories in the vertebrate brain. J. Comp. Neurol., 431:276-292

Roubert C., Sagné, C., Kapsimali, M., Vernier, P., Bourrat, F. and Giros, B. (2001) A Na+/Cl-dependent transporter for catecholamines, identified as a norepinephrine transporter (meNET), is expressed in the brain of the teleost fish medaka (Oryzias latipes). Mol. Pharmacol. 60: 462-473.