ZFIN Person: Bajoghli, Baubak

ZFIN ID: ZDB-PERS-060731-5

ZFIN ID: ZDB-PERS-060731-5

Bajoghli, Baubak

Email:	baubak.bajoghli@med.uni-tuebingen.de
URL:
Affiliation:	Bajoghli Lab
Address:	University Hospital Tübingen Division of Translational Oncology Otfried-Müller-Strasse 10 72076 Tübingen Germany
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ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

The overall aim of my research is to understand how the innate and adaptive immunity is regulated in fish.

PUBLICATIONS

Doll, L., Aghaallaei, N., Dick, A.M., Welte, K., Skokowa, J., Bajoghli, B. (2020) A zebrafish model for HAX1-associated congenital neutropenia. Haematologica. 106(5):1311-1320

Bajoghli, B., Dick, A.M., Claasen, A., Doll, L., Aghaallaei, N. (2019) Zebrafish and Medaka: Two Teleost Models of T-Cell and Thymic Development. International Journal of Molecular Sciences. 20(17)

Morishima, T., Krahl, A.C., Nasri, M., Xu, Y., Aghaallaei, N., Findik, B., Klimiankou, M., Ritter, M., Hartmann, M.D., Gloeckner, C.J., Stefańczyk, S., Lindner, C., Oswald, B., Bernhard, R., Hähnel, K., Hermanutz-Klein, U., Ebinger, M., Handgretinger, R., Casadei, N., Welte, K., Andre, M., Müller, P., Bajoghli, B., Skokowa, J. (2019) LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis. Blood. 134(14):1159-1175

Aghaallaei, N., Bajoghli, B. (2018) Making Thymus Visible: Understanding T-Cell Development from a New Perspective. Frontiers in immunology. 9:375

Doenz, G., Dorn, S., Aghaallaei, N., Bajoghli, B., Riegel, E., Aigner, M., Bock, H., Werner, B., Lindhorst, T., Czerny, T. (2018) The function of tcf3 in medaka embryos: efficient knockdown with pePNAs. BMC Biotechnology. 18:1

Kuri, P., Ellwanger, K., Kufer, T.A., Leptin, M., Bajoghli, B. (2017) A high-sensitivity, bi-directional reporter to monitor NF-κB activity in cell culture and zebrafish in real-time. Journal of Cell Science. 130(3):648-657

Bajoghli, B. (2013) Evolution and function of chemokine receptors in the immune system of lower vertebrates. European journal of immunology. 43(7):1686-1692

Bajoghli, B., Ramialison, M., Aghaallaei, N., Czerny, T., and Wittbrodt, J. (2009) Identification of starmaker-like in medaka as a putative target gene of Pax2 in the otic vesicle. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(11):2860-2866

Bajoghli, B., Aghaallaei, N., Hess, I., Rode, I., Netuschil, N., Tay, B.H., Venkatesh, B., Yu, J.K., Kaltenbach, S.L., Holland, N.D., Diekhoff, D., Happe, C., Schorpp, M., and Boehm, T. (2009) Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates. Cell. 138(1):186-197

Carl, M., Bianco, I.H., Bajoghli, B., Aghaallaei, N., Czerny, T., and Wilson, S.W. (2007) Wnt/Axin1/beta-Catenin Signaling Regulates Asymmetric Nodal Activation, Elaboration, and Concordance of CNS Asymmetries. Neuron. 55(3):393-405

Bajoghli, B. (2007) Evolution of the Groucho/Tle gene family: gene organization and duplication events.. Development genes and evolution. 217(8):613-618

Bajoghli, B., Aghaallaei, N., Soroldoni, D., and Czerny, T. (2007) The roles of Groucho/Tle in left-right asymmetry and Kupffer's vesicle organogenesis. Developmental Biology. 303(1):347-361

Soroldoni, D., Bajoghli, B., Aghaallaei, N., Czerny, T. (2007) Dynamic expression pattern of Nodal-related genes during left-right development in medaka. Gene expression patterns : GEP. 7(1-2):93-101

Aghaallaei, N., Bajoghli, B., Walter, I., Czerny, T. (2005) Duplicated members of the Groucho/Tle gene family in fish.. Developmental Dynamics : an official publication of the American Association of Anatomists. 234(1):143-50

Bajoghli, B., Aghaallaei, N., Heimbucher, T., and Czerny, T. (2004) An artificial promoter construct for heat-inducible misexpression during fish embryogenesis. Developmental Biology. 271(2):416-430

NON-ZEBRAFISH PUBLICATIONS
1: Bajoghli B, Guo P, Aghaallaei N, Hirano M, Strohmeier C, McCurley N, Bockman
DE, Schorpp M, Cooper MD, Boehm T. A thymus candidate in lampreys. Nature. 2011
Feb 3;470(7332):90-4. PubMed PMID: 21293377.

2: Aghaallaei N, Bajoghli B, Schwarz H, Schorpp M, Boehm T. Characterization of
mononuclear phagocytic cells in medaka fish transgenic for a cxcr3a:gfp reporter.
Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18079-84. Epub 2010 Oct 4. PubMed
PMID: 20921403; PubMed Central PMCID: PMC2964234.

3: Bajoghli B, Ramialison M, Aghaallaei N, Czerny T, Wittbrodt J. Identification
of starmaker-like in medaka as a putative target gene of Pax2 in the otic
vesicle. Dev Dyn. 2009 Nov;238(11):2860-6. PubMed PMID: 19795520.

4: Bajoghli B, Aghaallaei N, Jung G, Czerny T. Induction of otic structures by
canonical Wnt signalling in medaka. Dev Genes Evol. 2009 Aug;219(8):391-8. Epub
2009 Sep 16. PubMed PMID: 19760182; PubMed Central PMCID: PMC2773112.

5: Bajoghli B, Aghaallaei N, Hess I, Rode I, Netuschil N, Tay BH, Venkatesh B, Yu
JK, Kaltenbach SL, Holland ND, Diekhoff D, Happe C, Schorpp M, Boehm T. Evolution
of genetic networks underlying the emergence of thymopoiesis in vertebrates.
Cell. 2009 Jul 10;138(1):186-97. Epub 2009 Jun 25. PubMed PMID: 19559469.

6: Aghaallaei N, Takagi A, Boehm T, Bajoghli B. Genetic evidence for monozygotic
twinning in medaka fish. Mol Reprod Dev. 2009 May;76(5):430. PubMed PMID:
19197934.

7: Ramialison M, Bajoghli B, Aghaallaei N, Ettwiller L, Gaudan S, Wittbrodt B,
Czerny T, Wittbrodt J. Rapid identification of PAX2/5/8 direct downstream targets
in the otic vesicle by combinatorial use of bioinformatics tools. Genome Biol.
2008 Oct 1;9(10):R145. PubMed PMID: 18828907; PubMed Central PMCID: PMC2760872.

8: Carl M, Bianco IH, Bajoghli B, Aghaallaei N, Czerny T, Wilson SW.
Wnt/Axin1/beta-catenin signaling regulates asymmetric nodal activation,
elaboration, and concordance of CNS asymmetries. Neuron. 2007 Aug
2;55(3):393-405. PubMed PMID: 17678853; PubMed Central PMCID: PMC1940036.

9: Bajoghli B. Evolution of the Groucho/Tle gene family: gene organization and
duplication events. Dev Genes Evol. 2007 Aug;217(8):613-8. Epub 2007 Jul 12.
PubMed PMID: 17624551.

10: Aghaallaei N, Bajoghli B, Czerny T. Distinct roles of Fgf8, Foxi1, Dlx3b and
Pax8/2 during otic vesicle induction and maintenance in medaka. Dev Biol. 2007
Jul 15;307(2):408-20. Epub 2007 Apr 24. PubMed PMID: 17555740.

11: Bajoghli B, Aghaallaei N, Soroldoni D, Czerny T. The roles of Groucho/Tle in
left-right asymmetry and Kupffer's vesicle organogenesis. Dev Biol. 2007 Mar
1;303(1):347-61. Epub 2006 Nov 17. PubMed PMID: 17188260.

12: Heimbucher T, Murko C, Bajoghli B, Aghaallaei N, Huber A, Stebegg R, Eberhard
D, Fink M, Simeone A, Czerny T. Gbx2 and Otx2 interact with the WD40 domain of
Groucho/Tle corepressors. Mol Cell Biol. 2007 Jan;27(1):340-51. Epub 2006 Oct 23.
PubMed PMID: 17060451; PubMed Central PMCID: PMC1800652.

13: Hochmann S, Aghaallaei N, Bajoghli B, Soroldoni D, Carl M, Czerny T.
Expression of marker genes during early ear development in medaka. Gene Expr
Patterns. 2007 Jan;7(3):355-62. Epub 2006 Jul 27. PubMed PMID: 16950663.

14: Soroldoni D, Bajoghli B, Aghaallaei N, Czerny T. Dynamic expression pattern
of Nodal-related genes during left-right development in medaka. Gene Expr
Patterns. 2007 Jan;7(1-2):93-101. Epub 2006 Jun 6. PubMed PMID: 16831571.

15: Aghaallaei N, Bajoghli B, Walter I, Czerny T. Duplicated members of the
Groucho/Tle gene family in fish. Dev Dyn. 2005 Sep;234(1):143-50. PubMed PMID:
16059907.

16: Bajoghli B, Aghaallaei N, Czerny T. Groucho corepressor proteins regulate
otic vesicle outgrowth. Dev Dyn. 2005 Jul;233(3):760-71. PubMed PMID: 15861392.

17: Bajoghli B, Aghaallaei N, Heimbucher T, Czerny T. An artificial promoter
construct for heat-inducible misexpression during fish embryogenesis. Dev Biol.
2004 Jul 15;271(2):416-30. PubMed PMID: 15223344.