ZFIN Person: Owens, Kelly

ZFIN ID: ZDB-PERS-060622-3

Owens, Kelly

Email:	kowens@u.washington.edu
URL:
Affiliation:
Address:	Department of Biological Structure University of Washington Box 357420 Seattle, WA 98195-7420 USA
Country:
Phone:	(206) 616-2598, 616-7467
Fax:	(206) 543-1524
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Chowdhury, S., Owens, K.N., Herr, R.J., Jiang, Q., Chen, X., Johnson, G., Groppi, V.E., Raible, D.W., Rubel, E.W., Simon, J.A. (2017) Phenotypic Optimization of Urea-Thiophene Carboxamides to Yield Potent, Well Tolerated and Orally Active Protective Agents Against Aminoglycoside-Induced Hearing Loss. Journal of medicinal chemistry. 61(1):84-97

Stawicki, T.M., Hernandez, L., Esterberg, R., Linbo, T., Owens, K.N., Shah, A.N., Thapa, N., Roberts, B., Moens, C.B., Rubel, E.W., Raible, D.W. (2016) Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish. G3 (Bethesda). 6(7):2225-35

Stawicki, T.M., Owens, K.N., Linbo, T., Reinhart, K.E., Rubel, E.W., Raible, D.W. (2014) The zebrafish merovingian mutant reveals a role for pH regulation in hair cell toxicity and function. Disease models & mechanisms. 7:847-856

Vlasits, A.L., Simon, J.A., Raible, D.W., Rubel, E.W., and Owens, K.N.. (2012) Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin. Hearing Research. 294(1-2):153-165

Namdaran, P., Reinhart, K.E., Owens, K.N., Raible, D.W., and Rubel, E.W. (2012) Identification of modulators of hair cell regeneration in the zebrafish lateral line. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(10):3516-3528

Hailey, D.W., Roberts, B., Owens, K.N., Stewart, A.K., Linbo, T., Pujol, R., Alper, S.L., Rubel, E.W., and Raible, D.W. (2012) Loss of Slc4a1b Chloride/Bicarbonate Exchanger Function Protects Mechanosensory Hair Cells from Aminoglycoside Damage in the Zebrafish Mutant persephone. PLoS Genetics. 8(10):e1002971

Coffin, A.B., Ou, H., Owens, K.N., Santos, F., Simon, J.A., Rubel, E.W., and Raible, D.W. (2010) Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line. Zebrafish. 7(1):3-11

Coffin, A.B., Owens, K.N., Raible, D.W., and Rubel, E.W. (2009) Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line. Hearing Research. 253(1-2):42-51

Owens, K.N., Coffin, A.B., Hong, L.S., Bennett, K.O., Rubel, E.W., and Raible, D.W. (2009) Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways. Hearing Research. 253(1-2):32-41

Gorden, N.T., Arts, H.H., Parisi, M.A., Coene, K.L., Letteboer, S.J., van Beersum, S.E., Mans, D.A., Hikida, A., Eckert, M., Knutzen, D., Alswaid, A.F., Ozyurek, H., Dibooglu, S., Otto, E.A., Liu, Y., Davis, E.E., Hutter, C.M., Bammler, T.K., Farin, F.M., Dorschner, M., Topçu, M., Zackai, E.H., Rosenthal, P., Owens, K.N., Katsanis, N., Vincent, J.B., Hildebrandt, F., Rubel, E.W., Raible, D.W., Knoers, N.V., Chance, P.F., Roepman, R., Moens, C.B., Glass, I.A., and Doherty, D. (2008) CC2D2A Is Mutated in Joubert Syndrome and Interacts with the Ciliopathy-Associated Basal Body Protein CEP290. American journal of human genetics. 83(5):559-571

Owens, K.N., Santos, F., Roberts, B., Linbo, T., Coffin, A.B., Knisely, A.J., Simon, J.A., Rubel, E.W., and Raible, D.W. (2008) Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death. PLoS Genetics. 4(2):e1000020

Owens, K.N., Cunningham, D.E., Macdonald, G., Rubel, E.W., Raible, D.W., and Pujol, R. (2007) Ultrastructural analysis of aminoglycoside-induced hair cell death in the zebrafish lateral line reveals an early mitochondrial response. The Journal of comparative neurology. 502(4):522-543

NON-ZEBRAFISH PUBLICATIONS