ZFIN Person: La Du, Jane K.

ZFIN ID: ZDB-PERS-040213-5

La Du, Jane K.

Email:	jkladu@yahoo.com
URL:
Affiliation:	Tanguay Lab
Address:	Department of Environmental and Molecular Toxicology Oregon State University 1007 Agricultural and Life Sciences Building Corvallis, OR 97331 USA
Country:	United States
Phone:	(541) 737-6514
Fax:	(541) 737-7966
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Dasgupta, S., La Du, J.K., Garcia, G.R., Li, S., Tomono-Duval, K., Rericha, Y., Huang, L., Tanguay, R.L. (2023) A CRISPR-Cas9 mutation in sox9b long intergenic noncoding RNA (slincR) affects zebrafish development, behavior, and regeneration. Toxicological sciences : an official journal of the Society of Toxicology. 194(2):153-166

Wallis, D.J., La Du, J., Thunga, P., Elson, D., Truong, L., Kolluri, S.K., Tanguay, R.L., Reif, D.M. (2022) Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model. Frontiers in toxicology. 4:846221

Head, B., La Du, J., Tanguay, R.L., Kioussi, C., Traber, M.G. (2020) Vitamin E is necessary for zebrafish nervous system development. Scientific Reports. 10:15028

Garland, M.A., Sengupta, S., Mathew, L.K., Truong, L., de Jong, E., Piersma, A.H., La Du, J., Tanguay, R.L. (2019) Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration. Toxicology reports. 6:529-537

Broening, H.W., La Du, J., Carr, G.J., Nash, J.F., Truong, L., Tanguay, R.L. (2019) Determination of narcotic potency using a neurobehavioral assay with larval zebrafish. Neurotoxicology. 74:67-73

Garcia, G.R., Shankar, P., Dunham, C.L., Garcia, A., La Du, J.K., Truong, L., Tilton, S.C., Tanguay, R.L. (2018) Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA ( slincR) Using the Zebrafish Model. Environmental health perspectives. 126:117002

Gamble, J.T., Reed-Harris, Y., Barton, C.L., La Du, J., Tanguay, R., Greenwood, J.A. (2018) Quantification of glioblastoma progression in zebrafish xenografts: Adhesion to laminin alpha 5 promotes glioblastoma microtumor formation and inhibits cell invasion. Biochemical and Biophysical Research Communications. 506(4):833-839

Balik-Meisner, M., Truong, L., Scholl, E.H., La Du, J.K., Tanguay, R.L., Reif, D.M. (2018) Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure. Environmental health perspectives. 126:067010

Garcia, G.R., Goodale, B.C., Wiley, M.W., La Du, J.K., Hendrix, D.A., Tanguay, R.L. (2017) In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression.. Molecular pharmacology. 91(6):609-619

Chlebowski, A.C., Garcia, G.R., La Du, J.K., Bisson, W.H., Truong, L., Massey Simonich, S.L., Tanguay, R.L. (2017) Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs. Toxicological sciences : an official journal of the Society of Toxicology. 157:246-259

Chlebowski, A.C., La Du, J.K., Truong, L., Massey Simonich, S.L., Tanguay, R.L. (2017) Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing. Toxicology reports. 4:202-210

Bugel, S.M., Wehmas, L.C., La Du, J.K., Tanguay, R.L. (2016) Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium. Toxicology and applied pharmacology. 296:31-41

Goodale, B.C., La Du, J., Tilton, S.C., Sullivan, C.M., Bisson, W.H., Waters, K.M., Tanguay, R.L. (2015) Ligand-specific transcriptional mechanisms underlie aryl hydrocarbon receptor-mediated developmental toxicity of oxygenated PAHs. Toxicological sciences : an official journal of the Society of Toxicology. 147(2):397-411

Chen, J., Das, S.R., La Du, J., Corvi, M.M., Bai, C., Chen, Y., Liu, X., Zhu, G., Tanguay, R.L., Dong, Q., and Huang, C. (2013) Chronic PFOS exposures induce life stage-specific behavioral deficits in adult zebrafish and produce malformation and behavioral deficits in F1 offspring. Environmental toxicology and chemistry. 32(1):201-206

Chen, J., Huang, C., Truong, L., La Du, J., Tilton, S.C., Waters, K.M., Lin, K., Tanguay, R.L., and Dong, Q. (2012) Early life stage trimethyltin exposure induces ADP-ribosylation factor expression and perturbs the vascular system in zebrafish. Toxicology. 302(2-3):129-139

Corvi, M.M., Stanley, K.A., Peterson, T.S., Kent, M.L., Feist, S.W., La Du, J.K., Volz, D.C., Hosmer, A.J., and Tanguay, R.L. (2012) Investigating the Impact of Chronic Atrazine Exposure on Sexual Development in Zebrafish. Birth defects research. Part B, Developmental and reproductive toxicology. 95(4):276-288

Lal, S., La Du, J., Tanguay, R.L., and Greenwood, J.A. (2012) Calpain 2 is required for the invasion of glioblastoma cells in the zebrafish brain microenvironment. Journal of neuroscience research. 90(4):769-781

Goodale, B.C., La Du, J.K., Bisson, W.H., Janszen, D.B., Waters, K.M., and Tanguay, R.L. (2012) AHR2 Mutant Reveals Functional Diversity of Aryl Hydrocarbon Receptors in Zebrafish. PLoS One. 7(1):e29346

Yang, D., Lauridsen, H., Buels, K., Chi, L.H., La Du, J., Bruun, D., Olson, J.R., Tanguay, R.L., and Lein, P. (2011) Chlorpyrifos-Oxon Disrupts Zebrafish Axonal Growth and Motor Behavior. Toxicological sciences : an official journal of the Society of Toxicology. 121(1):146-59

Mathew, L.K., Sengupta, S., Franzosa, J., Perry, J., La Du, J., Andreasen, E.A., and Tanguay, R.L. (2009) Comparative expression profiling reveals an essential role for Raldh2 in epimorphic regeneration. The Journal of biological chemistry. 284(48):33642-33653

Tilton, F., La Du, J.K., and Tanguay, R.L. (2008) Sulfhydryl systems are a critical factor in the zebrafish developmental toxicity of the dithiocarbamate sodium metam (NaM). Aquatic toxicology (Amsterdam, Netherlands). 90(2):121-127

Tilton, F., La Du, J.K., Vue, M., Alzarban, N., and Tanguay, R.L. (2006) Dithiocarbamates have a common toxic effect on zebrafish body axis formation. Toxicology and applied pharmacology. 216(1):55-68

Reimers, M.J., La Du, J.K., Periera, C.B., Giovanini, J., and Tanguay, R.L. (2006) Ethanol-dependent toxicity in zebrafish is partially attenuated by antioxidants. Neurotoxicology and teratology. 28(4):497-508

NON-ZEBRAFISH PUBLICATIONS