ZFIN ID: ZDB-PERS-040105-1
Guyon, Jeff
Email: jguyon@enders.tch.harvard.edu
Address: Kunkel Lab Department of Genetics and Pediatrics Children's Hospital Boston Enders Building, 5th Floor 300 Longwood Avenue Boston, MA 02115 USA
Phone: (617) 355-4454
Fax: (617) 277-0496


Gupta, V., Discenza, M., Guyon, J.R., Kunkel, L.M., and Beggs, A.H. (2012) α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(5):1892-1908
Alexander, M.S., Kawahara, G., Kho, A.T., Howell, M.H., Pusack, T.J., Myers, J.A., Montanaro, F., Zon, L.I., Guyon, J.R., and Kunkel, L.M. (2011) Isolation and transcriptome analysis of adult zebrafish cells enriched for skeletal muscle progenitors. Muscle & nerve. 43(5):741-750
Kawahara, G., Karpf, J.A., Myers, J.A., Alexander, M.S., Guyon, J.R., and Kunkel, L.M. (2011) Drug screening in a zebrafish model of Duchenne muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 108(13):5331-6
Kawahara, G., Guyon, J.R., Nakamura, Y., and Kunkel, L.M. (2010) Zebrafish models for human FKRP muscular dystrophies. Human molecular genetics. 19(4):623-633
Sohn, R.L., Huang, P., Kawahara, G., Mitchell, M., Guyon, J., Kalluri, R., Kunkel, L.M., and Gussoni, E. (2009) A role for nephrin, a renal protein, in vertebrate skeletal muscle cell fusion. Proceedings of the National Academy of Sciences of the United States of America. 106(23):9274-9279
Guyon, J.R., Goswami, J., Jun, S.J., Thorne, M., Howell, M., Pusack, T., Kawahara, G., Steffen, L.S., Galdzicki, M., and Kunkel, L.M. (2009) Genetic isolation and characterization of a splicing mutant of zebrafish dystrophin. Human molecular genetics. 18(1):202-211
Steffen, L.S., Guyon, J.R., Vogel, E.D., Howell, M.H., Zhou, Y., Weber, G.J., Zon, L.I., and Kunkel, L.M. (2007) The zebrafish runzel muscular dystrophy is linked to the titin gene. Developmental Biology. 309(2):180-192
Langenau, D.M., Keefe, M.D., Storer, N.Y., Guyon, J.R., Kutok, J.L., Le, X., Goessling, W., Neuberg, D.S., Kunkel, L.M., and Zon, L.I. (2007) Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes & Development. 21(11):1382-1395
Steffen, L.S., Guyon, J.R., Vogel, E.D., Beltre, R., Pusack, T.J., Zhou, Y., Zon, L.I., and Kunkel, L.M. (2007) Zebrafish orthologs of human muscular dystrophy genes. BMC Genomics. 8(1):79
Guyon, J.R., Steffen, L.S., Howell, M.H., Pusack, T.J., Lawrence, C., and Kunkel, L.M. (2007) Modeling human muscle disease in zebrafish. Biochimica et biophysica acta. Molecular basis of disease. 1772(2):205-215
Kunkel, L.M., Bachrach, E., Bennett, R.R., Guyon, J., and Steffen, L. (2006) Diagnosis and cell-based therapy for Duchenne muscular dystrophy in humans, mice, and zebrafish. Journal of Human Genetics. 51(5):397-406
Guyon, J.R., Mosley, A.N., Jun, S.J., Montanaro, F., Steffen, L.S., Zhou, Y., Nigro, V., Zon, L.I., and Kunkel, L.M. (2005) delta-Sarcoglycan is required for early zebrafish muscle organization. Experimental cell research. 304(1):105-115
Guyon, J.R., Mosley, A.N., Zhou, Y., O'Brien, K.F., Sheng, X., Chiang, K., Davidson, A.J., Volinski, J.M., Zon, L.I., and Kunkel, L.M. (2003) The dystrophin associated protein complex in zebrafish. Human molecular genetics. 12(6):601-615

1. Guyon, J.R., Narlikar, G.J., Sif, S. and R.E. Kingston RE. 1999. Stable remodeling of tailless nucleosomes by the human SWI-SNF complex. Mol. Cell. Biol. 19:2088-97.

2. Shao, Z., Raible, F., Mollaaghababa, R., Guyon, J.R., Wu, C.T., Bender, W. and R.E. Kingston. 1999. Stabilization of chromatin structure by PRC1, a Polycomb complex. Cell 98:37-46.

3. Kwon, J., Morshead, K.B., Guyon, J.R., Kingston, R.E. and M.A. Oettinger. 2000. Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol Cell. 6:1037-48.

4. Guyon, J.R., Narlikar, G.J., Sullivan, E.K. and R.E. Kingston. 2001. Stability of a human SWI-SNF remodeled nucleosomal array. Mol. Cell. Biol. 21:1132-44.

5. Sullivan, E.K., Weirich, C.S., Guyon, J.R., Sif, S., and R.E. Kingston. 2001. Transcriptional activation domains of human heat shock factor 1 recruit human SWI/SNF. Mol. Cell. Biol. 2001. 21:5826-37.

6. Mizuno, Y., Thompson, T.G., Guyon, J.R., Lidov, H.G., Brosius, M., Imamura, M., Ozawa, E., Watkins, S.C. and L.M. Kunkel. 2001. Desmuslin, an intermediate filament protein that interacts with alpha -dystrobrevin and desmin. Proc. Natl. Acad. Sci. USA 98:6156-61.

7. Spencer, M.J., Guyon, J.R., Sorimachi, H., Potts, A., Richard, I., Herasse, M., Chamberlain, J., Dalkilic, I., Kunkel, L.M., and J.S. Beckman. 2002. Stable expression of calpain-3 from a muscle transgene in vivo: Immature muscle in transgenic mice suggests a role for calpain-3 in muscle degeneration. Proc. Natl. Acad. Sci. USA 99:8874-9.

8. Guyon, J.R., Kudryashova, E., Potts, A., Dalkilic, I., Brosius, M., Thompson, T.G., Beckmann, J.S., Kunkel, L.M. and M.J. Spencer. 2003. Calpain 3 cleaves filamin c and regulates its ability to interact with gamma and delta sarcoglycans. Muscle Nerve. 28:472-83.