ZFIN ID: ZDB-PERS-030918-7
Clements, Wilson
Email: wilson.clements@stjude.org
URL: http://www.stjude.org/clements
Affiliation: Clements Lab
Address: Department of Hematology Division of Experimental Hematology St Jude Children's Research Hospital MS-355, 262 Danny Thomas Pl. Memphis, TN 38105
Country: United States
Phone: (901) 595-5940
Fax: (901) 595-4723
ORCID ID: 0000-0003-4365-9553


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Koirala, S., Klein, J., Zheng, Y., Glenn, N.O., Eisemann, T., Fon Tacer, K., Miller, D.J., Kulak, O., Lu, M., Finkelstein, D.B., Neale, G., Tillman, H., Vogel, P., Strand, D.W., Lum, L., Brautigam, C.A., Pascal, J.M., Clements, W.K., Potts, P.R. (2020) Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Cell Reports. 32:107922
da Bandeira, D.S., Clements, W.K. (2020) MYC'xing it up: zebrafish B ALL models provide insight into MYC-driven disease and relapse. Oncotarget. 11:2372-2374
Genthe, J.R., Min, J., Farmer, D.M., Shelat, A.A., Grenet, J.A., Lin, W., Finkelstein, D.B., Vrijens, K., Chen, T., Guy, R.K., Clements, W.K., Roussel, M.F. (2017) Ventromorphins: A new class of small molecule activators of the canonical BMP signaling pathway. ACS Chemical Biology. 12(9):2436-2447
Damm, E.W., Clements, W.K. (2017) Pdgf signalling guides neural crest contribution to the haematopoietic stem cell specification niche. Nature cell biology. 19(5):457-467
Genthe, J.R., Clements, W.K. (2017) R-spondin-1 is required for specification of hematopoietic stem cells through Wnt16 and Vegfa signaling pathways. Development (Cambridge, England). 144(4):590-600
Lee, Y., Manegold, J.E., Kim, A.D., Pouget, C., Stachura, D.L., Clements, W.K., Traver, D. (2014) FGF signalling specifies haematopoietic stem cells through its regulation of somitic Notch signalling. Nature communications. 5:5583
Kim, A.D., Melick, C.H., Clements, W.K., Stachura, D.L., Distel, M., Panáková, D., MacRae, C., Mork, L.A., Crump, J.G., Traver, D. (2014) Discrete Notch signaling requirements in the specification of hematopoietic stem cells. The EMBO journal. 33(20):2363-73
Clements, W.K., and Traver, D. (2012) Fish pharming: zebrafish antileukemia screening. Blood. 119(24):5614-5615
Clements, W.K., Kim, A.D., Ong, K.G., Moore, J.C., Lawson, N.D., and Traver, D. (2011) A somitic Wnt16/Notch pathway specifies haematopoietic stem cells. Nature. 474(7350):220-224
Clements, W.K., Ong, K.G., and Traver, D. (2009) Zebrafish wnt3 is expressed in developing neural tissue. Developmental dynamics : an official publication of the American Association of Anatomists. 238(7):1788-1795
Clements, W.K., and Kimelman, D. (2005) LZIC regulates neuronal survival during zebrafish development. Developmental Biology. 283(2):322-334

NON-ZEBRAFISH PUBLICATIONS
Clements, W.K. and Kimelman, D. "Analysis of Wnt Signaling in Embryos" in Analysis of Growth Factor Signaling in Embryos. Whitman, M. and Sater, A.K., eds. CRC Press. In press.

Xing, Y., Clements, W.K., Trong, I.L., Hinds, T.R., Stenkamp, R., Kimelman, D., and Xu, W. Crystal structure of a Beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function. Mol. Cell. 15:523-533, 2004.

Xing, Y., Clements, W.K., Kimelman, D., and Xu, W. Crystal structure of a Beta-catenin/Axin complex suggests a mechanism for the Beta-catenin destruction complex. Genes & Dev. 17:2753-2764, 2003.

Clements, W.K. and Kimelman, D. Wnt Signaling Gets Xeeky. Nat. Cell Biol. 5:861-863, 2003.

Graham, T.A., Clements, W.K., Kimelman, D., and Xu, W. The crystal structure of the Beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT. Mol. Cell. 10:563-571, 2002.

Melby, A.E., Clements, W.K., and Kimelman, D. Regulation of dorsal gene expression in Xenopus by the ventralizing homeodomain gene Vox. Dev. Biol. 15:293-305, 1999.