Person
Andersen, Søren S. L.
|
|
Biography and Research Interest
+------------------------------------------------------------------------------+
Title: ZEBRAFISH AS A MODEL SYSTEM IN NEUROBIOLOGY.
IN PARTICULAR: axonal wiring and synaptogenesis using combined in vitro and in vivo strategies.
IN VIVO: Light-sheet microscopy (SPIM = Single Plane Illumination Microscopy) has become available and is a good choice to use with the transparent larval zebrafish for in vivo imaging of, for example, midline crossing axons at the ventral spinal cord, as demonstrated in the 2019 paper "Real time large scale in vivo observations reveal intrinsic synchrony, plasticity and growth cone dynamics of midline crossing axons at the ventral floor plate of the zebrafish spinal cord" (https://www.sorenandersen.org/publications/RealTimeInVivoObservationsZebrafish2019.pdf).
IN VITRO: There is increasing interest and application of zebrafish-based dissociated spinal neuron cultures [outlined in refs. (2001) and (2003), hereunder] for cellular neurobiology and electrophysiology related questions (e.g.: PLoS ONE, 2013, 8(6):e67276; Dis Model Mech, 2013, 6: 404-413; PLoS ONE, 2013, 8(3):e57539; J Neurosci Meth, 2012, 205(2): 277-282; Dev Dynam, 2010, 239(9): 2501-2508; Nat Neurosci, 2010, 13(11): 1380-1388; Dev Neurobiol, 2009, 69(8): 518-29; J Neuroendocrinol, 2009, 21: 489-505; Neurosci Lett, 2007, 411(2): 128-32).
Title: ZEBRAFISH AS A MODEL SYSTEM IN NEUROBIOLOGY.
IN PARTICULAR: axonal wiring and synaptogenesis using combined in vitro and in vivo strategies.
IN VIVO: Light-sheet microscopy (SPIM = Single Plane Illumination Microscopy) has become available and is a good choice to use with the transparent larval zebrafish for in vivo imaging of, for example, midline crossing axons at the ventral spinal cord, as demonstrated in the 2019 paper "Real time large scale in vivo observations reveal intrinsic synchrony, plasticity and growth cone dynamics of midline crossing axons at the ventral floor plate of the zebrafish spinal cord" (https://www.sorenandersen.org/publications/RealTimeInVivoObservationsZebrafish2019.pdf).
IN VITRO: There is increasing interest and application of zebrafish-based dissociated spinal neuron cultures [outlined in refs. (2001) and (2003), hereunder] for cellular neurobiology and electrophysiology related questions (e.g.: PLoS ONE, 2013, 8(6):e67276; Dis Model Mech, 2013, 6: 404-413; PLoS ONE, 2013, 8(3):e57539; J Neurosci Meth, 2012, 205(2): 277-282; Dev Dynam, 2010, 239(9): 2501-2508; Nat Neurosci, 2010, 13(11): 1380-1388; Dev Neurobiol, 2009, 69(8): 518-29; J Neuroendocrinol, 2009, 21: 489-505; Neurosci Lett, 2007, 411(2): 128-32).
Non-Zebrafish Publications
Andersen S.S.L, Jackson AD, Heimburg T. (2009). Towards a thermodynamic theory of nerve pulse propagation. Progress in Neurobiology, 88(2), 104-113.Andersen S.S.L. (2005). The search and prime hypothesis for growth cone turning. BioEssays, 27(1), 86-90.
Andersen S.S.L. (2000). Spindle assembly and the art of regulating microtubule dynamics by MAPs and Stathmin/Op18. Trends Cell Biol., 10(7), 261-267.
Andersen S.S.L. and Bi GQ. (2000). Axon formation: a molecular model for the generation of neuronal polarity. BioEssays, 22(2), 172-179.