ZFIN ID: ZDB-PERS-030211-14
McLoughlin, Sarah
Address: Department of Biochemistry National University of Ireland University Road Galway, Ireland
Phone: 353-91-512375
Fax: 353-91-525700

Our current research interests lie in the following areas:

1. Molecular and cellular events at the midblastula transition in zebrafish.

2. The developmental role of the IGF-1 receptor during embryonic development, using zebrafish as a model species.

Glaviano, A., Smith, A.J., Blanco, A., McLoughlin, S., Cederlund, M.L., Heffernan, T., Sapetto-Rebow, B., Alvarez, Y., Yin, J., Kennedy, B.N. (2016) A method for isolation of cone photoreceptors from adult zebrafish retinae. BMC Neuroscience. 17:71
Yin, J., Shine, L., Raycroft, F., Deeti, S., Reynolds, A., Ackerman, K.M., Glaviano, A., O'Farrell, S., O'Leary, O., Kilty, C., Kennedy, C., McLoughlin, S., Rice, M., Russell, E., Higgins, D.G., Hyde, D.R., and Kennedy, B.N. (2012) Inhibition of the pim1 oncogene results in diminished visual function. PLoS One. 7(12):e52177
Sapetto-Rebow, B., McLoughlin, S.C., O'Shea, L.C., O'Leary, O., Willer, J.R., Alvarez, Y., Collery, R., O'Sullivan, J., Van Eeden, F., Hensey, C., and Kennedy, B.N. (2011) Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants. BMC Developmental Biology. 11(1):71
Yin, J., McLoughlin, S., Jeffery, I.B., Glaviano, A., Kennedy, B., and Higgins, D.G. (2010) Integrating multiple genome annotation databases improves the interpretation of microarray gene expression data. BMC Genomics. 11:50
Collery, R., McLoughlin, S., Vendrell, V., Finnegan, J., Crabb, J.W., Saari, J.C., and Kennedy, B.N. (2008) Duplication and divergence of zebrafish CRALBP genes uncovers novel role for RPE- and Muller-CRALBP in cone vision. Investigative ophthalmology & visual science. 49(9):3812-3820
O'Boyle, S., Bree, R.T., McLoughlin, S., Grealy, M., and Byrnes, L. (2007) Identification of zygotic genes expressed at the midblastula transition in zebrafish. Biochemical and Biophysical Research Communications. 358(2):462-468
Bree, R.T., McLoughlin, S., Jin, S.W., McMeel, O.M., Stainier, D.Y., Grealy, M., and Byrnes, L. (2005) nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish. Biochemical and Biophysical Research Communications. 333(3):722-728