ZFIN ID: ZDB-PERS-020424-3
Beis, Dimitris
Email: dbeis@uoi.gr
URL: http://www.zebrafish.gr
Affiliation: Beis Lab
Address: Foundation for Biomedical Research of the Academy of Athens Basic Research Center, Cell Biology SORANOU EFESIOU 4 Athens, 115 27 Greece
Country: Greece
Phone: +30 210 6597240
Fax: +30 210 6597545
ORCID ID: 0000-0003-2579-7848


Kolb, J., Tsata, V., John, N., Kim, K., Möckel, C., Rosso, G., Kurbel, V., Parmar, A., Sharma, G., Karandasheva, K., Abuhattum, S., Lyraki, O., Beck, T., Müller, P., Schlüßler, R., Frischknecht, R., Wehner, A., Krombholz, N., Steigenberger, B., Beis, D., Takeoka, A., Blümcke, I., Möllmert, S., Singh, K., Guck, J., Kobow, K., Wehner, D. (2023) Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment. Nature communications. 14:68146814
Giardoglou, P., Deloukas, P., Dedoussis, G., Beis, D. (2023) Cfdp1 Is Essential for Cardiac Development and Function. Cells. 12(15):
Siatra, P., Vatsellas, G., Chatzianastasiou, A., Balafas, E., Manolakou, T., Papapetropoulos, A., Agapaki, A., Mouchtouri, E.T., Ruchaya, P.J., Korovesi, A.G., Mavroidis, M., Thanos, D., Beis, D., Kokkinopoulos, I. (2023) Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart. NPJ Regenerative medicine. 8:1313
Leonidis, G., Koukiali, A., Sigala, I., Tsimaratou, K., Beis, D., Giannakouros, T., Nikolakaki, E., Sarli, V. (2023) Synthesis and Anti-Angiogenic Activity of Novel c(RGDyK) Peptide-Based JH-VII-139-1 Conjugates. Pharmaceutics. 15(2):
Katraki-Pavlou, S., Kastana, P., Bousis, D., Ntenekou, D., Varela, A., Davos, C.H., Nikou, S., Papadaki, E., Tsigkas, G., Athanasiadis, E., Herradon, G., Mikelis, C.M., Beis, D., Papadimitriou, E. (2021) Protein tyrosine phosphatase receptor zeta 1 deletion triggers defective heart morphogenesis in mice and zebrafish. American journal of physiology. Heart and circulatory physiology. 322(1):H8-H24
Leonidis, G., Dalezis, P., Trafalis, D., Beis, D., Giardoglou, P., Koukiali, A., Sigala, I., Nikolakaki, E., Sarli, V. (2021) Synthesis and Biological Evaluation of a c(RGDyK) Peptide Conjugate of SRPIN803. ACS omega. 6:28379-28393
Beis, D. (2021) Zebrafish research in Greece: swimming against the current. The International journal of developmental biology. 66(1-2-3):155-161
Giardoglou, P., Bournele, D., Park, M., Kanoni, S., Dedoussis, G.V., Steinberg, S.F., Deloukas, P., Beis, D. (2021) A Zebrafish Forward Genetic Screen Identifies an Indispensible Threonine Residue in the Kinase Domain of PRKD2. Biology Open. 10(3):
Tsata, V., Möllmert, S., Schweitzer, C., Kolb, J., Möckel, C., Böhm, B., Rosso, G., Lange, C., Lesche, M., Hammer, J., Kesavan, G., Beis, D., Guck, J., Brand, M., Wehner, D. (2020) A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord. Developmental Cell. 56(4):509-524.e9
Kakouri, E., Agalou, A., Kanakis, C., Beis, D., Tarantilis, P.A. (2020) Crocins from Crocus sativus L. in the Management of Hyperglycemia. In Vivo Evidence from Zebrafish. Molecules. 25(22):
Katsouda, A., Peleli, M., Asimakopoulou, A., Papapetropoulos, A., Beis, D. (2020) Generation and Characterization of a CRISPR/Cas9 -Induced 3-mst Deficient Zebrafish. Biomolecules. 10(2):
Bensimon-Brito, A., Ramkumar, S., Boezio, G.L.M., Guenther, S., Kuenne, C., Helker, C.S.M., Sánchez-Iranzo, H., Iloska, D., Piesker, J., Pullamsetti, S., Mercader, N., Beis, D., Stainier, D.Y.R. (2019) TGF-β Signaling Promotes Tissue Formation during Cardiac Valve Regeneration in Adult Zebrafish. Developmental Cell. 52(1):9-20.e7
Kefalos, P., Agalou, A., Kawakami, K., Beis, D. (2019) Reactivation of Notch signaling is required for cardiac valve regeneration. Scientific Reports. 9:16059
Sarantis, P., Gaitanaki, C., Beis, D. (2019) Ventricular remodeling of single-chambered myh6-/- adult zebrafish hearts occurs via a hyperplastic response and is accompanied by elastin deposition in the atrium. Cell and tissue research. 378(2):279-288
Psarras, S., Beis, D., Nikouli, S., Tsikitis, M., Capetanaki, Y. (2019) Three in a Box: Understanding Cardiomyocyte, Fibroblast, and Innate Immune Cell Interactions to Orchestrate Cardiac Repair Processes. Frontiers in cardiovascular medicine. 6:32
Dimitriadi, A., Beis, D., Arvanitidis, C., Adriaens, D., Koumoundouros, G. (2018) Developmental temperature has persistent, sexually dimorphic effects on zebrafish cardiac anatomy. Scientific Reports. 8:8125
Agalou, A., Thrapsianiotis, M., Angelis, A., Papakyriakou, A., Skaltsounis, A.L., Aligiannis, N., Beis, D. (2018) Identification of Novel Melanin Synthesis Inhibitors From Crataegus pycnoloba Using an in Vivo Zebrafish Phenotypic Assay.. Frontiers in pharmacology. 9:265
Chaita, E., Lambrinidis, G., Cheimonidi, C., Agalou, A., Beis, D., Trougakos, I., Mikros, E., Skaltsounis, A.L., Aligiannis, N. (2017) Anti-Melanogenic Properties of Greek Plants. A Novel Depigmenting Agent from Morus alba Wood. Molecules. 22(4)
Serifi, I., Tzima, E., Soupsana, K., Karetsou, Z., Beis, D., Papamarcaki, T. (2016) The zebrafish homologs of SET/I2PP2A oncoprotein: expression patterns and insights into their physiological roles during development. The Biochemical journal. 473(24):4609-4627
Bournele, D., Beis, D. (2016) Zebrafish models of cardiovascular disease. Heart failure reviews. 21(6):803-813
Malissovas, N., Griffin, L.B., Antonellis, A., Beis, D. (2016) Dimerization is required for GARS-mediated neurotoxicity in dominant CMT disease. Human molecular genetics. 25:1528-42
Papakyriakou, A., Kefalos, P., Sarantis, P., Tsiamantas, C., Xanthopoulos, K.P., Vourloumis, D., Beis, D. (2014) A zebrafish in vivo phenotypic assay to identify 3-aminothiophene-2-carboxylic Acid-based angiogenesis inhibitors. Assay and drug development technologies. 12:527-35
Kalogirou, S., Malissovas, N., Moro, E., Argenton, F., Stainier, D.Y., Beis, D. (2014) Intracardiac Flow Dynamics Regulate Atrioventricular Valve Morphogenesis. Cardiovascular research. 104(1):49-60
Moro, E., Özhan, G., Mongera, A., Beis, D., Wierzbicki, C., Young, R.M., Bournele, D., Domenichini, A., Valdivia, L.E., Lum, L., Chen, C., Amatruda, J.F., Tiso, N., Weidinger, G., and Argenton, F. (2012) In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains. Developmental Biology. 366(2):327-340
Serafimidis, I., Heximer, S., Beis, D., and Gavalas, A. (2011) GPCR signaling and S1P play a phylogenetically conserved role in endocrine pancreas morphogenesis. Molecular and cellular biology. 31(22):4442-53
Chi, N.C., Shaw, R.M., Jungblut, B., Huisken, J., Ferrer, T., Arnaout, R., Scott, I., Beis, D., Xiao, T., Baier, H., Jan, L.Y., Tristani-Firouzi, M., and Stainier, D.Y. (2008) Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System. PLoS Biology. 6(5):e109
Jin, S.W., Herzog, W., Santoro, M.M., Mitchell, T.S., Frantsve, J., Jungblut, B., Beis, D., Scott, I.C., D'Amico, L.A., Ober, E.A., Verkade, H., Field, H.A., Chi, N.C., Wehman, A.M., Baier, H., and Stainier, D.Y. (2007) A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos. Developmental Biology. 307(1):29-42
Pyriochou, A., Beis, D., Koika, V., Polytarchou, C., Papadimitriou, E., Zhou, Z., and Papapetropoulos, A. (2006) Soluble guanylyl cyclase activation promotes angiogenesis. The Journal of pharmacology and experimental therapeutics. 319(2):663-671
Beis, D., and Stainier, D.Y. (2006) In vivo cell biology: following the zebrafish trend. Trends in cell biology. 16(2):105-112
Jin, S.W., Beis, D., Mitchell, T., Chen, J.N., Stainier, D.Y. (2005) Cellular and molecular analyses of vascular tube and lumen formation in zebrafish. Development (Cambridge, England). 132(23):5199-5209
Beis, D., Bartman, T., Jin, S.W., Scott, I.C., D'Amico, L.A., Ober, E.A., Verkade, H., Frantsve, J., Field, H.A., Wehman, A., Baier, H., Tallafuss, A., Bally-Cuif, L., Chen, J.N., Stainier, D.Y., and Jungblut, B. (2005) Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development (Cambridge, England). 132(18):4193-4204
Parker, L.H., Schmidt, M., Jin, S.W., Gray, A.M., Beis, D., Pham, T., Frantz, G., Palmieri, S., Hillan, K., Stainier, D.Y., De Sauvage, F.J., Ye, W. (2004) The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation. Nature. 425(6984):754-758
Field, H.A., Dong, P.D., Beis, D., and Stainier, D.Y. (2003) Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Developmental Biology. 261(1):197-208
Stainier, D.Y., Beis, D., Jungblut, B., and Bartman, T. (2002) Endocardial cushion formation in zebrafish. Cold Spring Harbor symposia on quantitative biology. 67:49-56

Aida M*, Beis D*, Heidstra R, Willemsen V, Blilou I, Galinha C, Nussaume L, Noh YS, Amasino R, Scheres B.
The PLETHORA genes mediate patterning of the Arabidopsis root stem cell niche. Cell. 2004 Oct 1;119(1):109-20.

Sabatini S*, Beis D*, Wolkenfelt H, Murfett J, Guilfoyle T, Malamy J, Benfey P, Leyser O, Bechtold N, Weisbeek P, Scheres B.
An auxin-dependent distal organizer of pattern and polarity in the Arabidopsis root. Cell. 1999 Nov 24;99(5):463-72.